作者：
Wang, Robin;Jiao, Zhicheng;Li Yang;Choi, Ji Whae;Xiong, Zeng;...
期刊：
European Radiology,2022年32(1):205-212 ISSN：0938-7994
通讯作者：
Liao, Wei-Hua;Bai, Harrison X.
作者机构：
[Liao, Wei-Hua; Yang, Shuai; Wang, Robin; Xiong, Zeng; Wang, Dong-Cui; Yi, Xiao-Ping; Zhu, Li-Ping] Cent South Univ, Xiangya Hosp, Dept Radiol, Changsha, Peoples R China.;[Zhang, Paul J. L.; Sebro, Ronnie A.; Jiao, Zhicheng; Wang, Robin; Fan, Yong] Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA.;[Zhang, Paul J. L.; Sebro, Ronnie A.; Jiao, Zhicheng; Wang, Robin; Fan, Yong] Univ Penn, Ctr Biomed Image Computat & Analyt, Philadelphia, PA 19104 USA.;[Li Yang] Cent South Univ, Xiangya Hosp 2, Dept Neurol, Changsha, Peoples R China.;[Choi, Ji Whae; Tran, Thi My Linh; Atalay, Michael K.; Halsey, Kasey; Pan, Ian; Bai, Harrison X.; Collins, Scott A.; Healey, Terrance T.] Rhode Isl Hosp, Dept Diagnost Imaging, Providence, RI 02903 USA.
通讯机构：
[Liao, Wei-Hua] C;[Bai, Harrison X.] R;[Bai, Harrison X.] B;Cent South Univ, Xiangya Hosp, Dept Radiol, Changsha, Peoples R China.;Rhode Isl Hosp, Dept Diagnost Imaging, Providence, RI 02903 USA.
摘要：
Pyroptosis is a newly discovered form of programmed cell death mediated by the gasdermin protein, that is accompanied by inflammation and immune response. A growing body of evidence suggests that pyroptosis is closely related to cancer, and it is becoming a new cancer research topic. Studies have suggested that different cancer cells activate pyroptosis in different ways and that the effects of pyroptosis vary in different cancer backgrounds. In this article, we briefly introduce the definition, characteristics, and activation pathways of pyroptosis. Then we review the complex effects of pyroptosis on cancer development, which generally include inhibition of cancer cell viability, impacts on the invasion and migration of cancer cells, improvement of antitumor immunity, and enhancement of chemotherapy sensitivity. We also discuss drugs and compounds that can induce pyroptosis, as well as the interaction between pyroptosis and apoptosis. Elucidating the mechanisms of the complex effects of pyroptosis is likely to pave the way for therapeutic approaches for cancer in the future.
通讯机构：
[Zhaoyang Wu] S;State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, People’s Republic of China
通讯机构：
[Huijun Liu] S;School of Chemistry and Chemical Engineering, University of South China, Hengyang, People’s Republic of China<&wdkj&>Hunan Key Laboratory for the Design and Application of Actinide Complexes, University of South China, Hengyang, People’s Republic of China
摘要：
As a famous metal-organic framework (MOF) material, HKUST-1 has a high density of open metal sites and a moderate pore size. Moreover, it is usually used for liquid phase adsorption because of its good water resistance. However, the traditional hydrothermal method has the disadvantages of slow synthesis speed, harsh experimental processes and unsafe experimental conditions. Herein, HKUST-1 had been synthesized under room temperature through a quickly and convenient way. Synthesized HKUST-1 showed good adsorption capacity of europium(III) (135.32 mg/g) at pH = 6. The results indicated that the adsorption procedure obeys quasi-second-order kinetic model and Langmuir isothermal model.
摘要：
Background: Outdoor traffic-related air pollution has negative effects on respiratory health. In this study, we aimed to explore the effect of outdoor traffic-related air pollution on chronic obstructive pulmonary disease (COPD) in Guangzhou. Methods: We enrolled 1,460 residents aged 40 years or older between 21 January 2014 and 31 January 2018. We administered questionnaires and spirometry tests. The distance of participants' residences or locations of outdoor activities from busy roads (as indicators of outdoor traffic-related air pollution), indoor air pollution, and smoking history were queried in the questionnaires. Results: Of the 1,460 residents with valid survey and test results, 292 were diagnosed with COPD, with a detection rate of 20%. Participants who lived and did their outdoor activities near busy roads had a higher detection rate of COPD. Among residents living at distances of <50 meters, 50–199 meters, and more than 200 meters from busy roads, the detection rates were 20.6, 21.2, and 14.8%, respectively; the rates for outdoor activities at these distances were 23.8, 24.5, and 13.7%, respectively (p < 0.05). After adjusting for sex, age, smoking status, family history, and smoking index, the distance of outdoor activities from busy roads was an independent risk factor for COPD. Participants whose outdoor activities were conducted <50 meters and 50–199 meters of main roads had odds ratios of 1.54 (95% confidence interval 1.01–2.36) and 1.84 (95% interval 1.23–2.76) for the risk of COPD in comparison with a distance of more than 200 meters from busy roads. Conclusions: Residents of Guangzhou whose outdoor activities were close to busy roads had a high risk of COPD. Traffic-related air pollution presents a risk to human health and a risk of COPD.
通讯机构：
[Zehua Yang] H;[Zhengxing Wu; Wanbin Zhang] S;Hunan Provincial Key Laboratory of Tumor Microenvironment Responsive Drug Research, Institute of Pharmacy & Pharmacology School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001 China<&wdkj&>Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Frontiers Science Center for Transformative Molecules, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240 China
期刊：
Journal of Neuroinflammation,2022年19(1):1-14 ISSN：1742-2094
通讯作者：
Lili Cui
作者机构：
[Cui, Lili; Chen, Feng; Chen, Yanting] Guangdong Med Univ, Affiliated Hosp, Guangdong Key Lab Age Related Cardiac & Cerebral, Dept Neurol, Zhanjiang 524000, Peoples R China.;[Yang, Wenren] Univ South China, Affiliated Nanhua Hosp, Hengyang Med Sch, Dept Trauma Ctr, Hengyang 421002, Peoples R China.
通讯机构：
[Lili Cui] D;Department of Neurology, Guangdong Key Laboratory of Age-Related Cardiac and Cerebral Diseases, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China
摘要：
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a global pandemic. Although COVID-19 was initially described as a respiratory disease, there is growing evidence that SARS-CoV-2 is able to invade the brains of COVID-19 patients and cause cognitive impairment. It has been reported that SARS-CoV-2 may have invasive effects on a variety of cranial nerves, including the olfactory, trigeminal, optic, and vagus nerves, and may spread to other brain regions via infected nerve endings, retrograde transport, and transsynaptic transmission. In addition, the blood–brain barrier (BBB), composed of neurovascular units (NVUs) lining the brain microvasculature, acts as a physical barrier between nerve cells and circulating cells of the immune system and is able to regulate the transfer of substances between the blood and brain parenchyma. Therefore, the BBB may be an important structure for the direct and indirect interaction of SARS-CoV-2 with the brain via the blood circulation. In this review, we assessed the potential involvement of neuroinvasion under the SARS-CoV-2 infection, and the potential impact of BBB disorder under SARS-CoV-2 infection on cognitive impairment.
作者机构：
[Luo, Xiao-Yan] Univ South China, Dept Med Serv, Affiliated Nanhua Hosp, Hengyang 421002, Hunan, Peoples R China.;[Luo, Xiao-Yan] Hlth Sch Nucl Ind, Hengyang 421002, Hunan, Peoples R China.;[Ying, Jian-Hua] Univ South China, Dept Outpatient, Affiliated Nanhua Hosp, Hengyang 421002, Hunan, Peoples R China.;[Wang, Qiao-Sheng] Univ South China, Dept Crit Care Med, Affiliated Hosp 1, 69 Chuanshan Rd, Hengyang 421001, Hunan, Peoples R China.
通讯机构：
[Qiao-Sheng Wang] D;Department of Critical Care Medicine, The First Affiliated Hospital of University of South China, No. 69 Chuanshan Road, Hunan Province, Hengyang, China
摘要：
Alterations in thermal hydraulic parameters directly affect the safety of reactors. Accurately predicting the trends of key thermal hydraulic parameters under various working conditions can greatly improve reactor safety, thereby effectively preventing the occurrence of nuclear power plant accidents. The thermal hydraulic characteristic parameters in the reactor are affected by many factors, in order to preliminarily study whose forecasting methods and determine the feasibility of neural network forecasting, the China Experimental Fast Reactor (CEFR) is selected as the research target in this study, and the maximum surface temperature of fuel rod sheath and mass flow rate are used as predictive variables. After data samples are generated through the reactor sub channel analysis code (named SUBCHANFLOW), two widely used adaptive neural networks are used to perform the thermal hydraulic parameter forecast analysis of CEFR fuel assembly under steady-state conditions. The 1/2 core model of CEFR is used to perform a single-step predictive analysis of thermal hydraulic parameters under transient conditions. The results show that the adaptive radial basis function (RBF) neural network exhibits a better fitting ability and higher forecasting accuracy than that of the adaptive back propagation neural network, and the maximum error under steady-state conditions is 0.5%. Under transient conditions, poor forecasting accuracy is observed for some local points; however, the adaptive RBF neural network is generally excellent at predicting temperature and mass flow. The mean relative error of temperature does not exceed 1%, and the mean relative error of flow does not exceed 6.5%. The proposed RBF neural network model can provide real-time forecasting in a short time under unstable flow conditions, and its forecasting results have a certain reference value.
摘要：
Alzheimer's disease (AD) is one of the most common causes of neurodegenerative diseases in the elderly. Cholinergic dysfunction is one of the pathological hallmarks of AD and leads to learning and memory impairment. Transient receptor potential vanilloid 4 (TRPV4), a nonselective cation channel, is involved in learning and memory functions. HC067047, a TRPV4 specific inhibitor, has been reported to protect neurons against cerebral ischemic injury and amyloid-β-(Aβ) 40-induced hippocampal cell death. However, whether HC067047 could improve scopolamine (SCP)-induced cognitive dysfunction in mice is still unknown. The aims of this study were to verify whether HC067047 could ameliorate the SCP-induced learning and memory impairments in mice and to elucidate its underlying mechanisms of action. In this study, we examined the neuroprotective effect of the HC067047 against cognitive dysfunction induced by SCP (5 mg/kg, i.p.), a muscarinic receptor antagonist. The results showed that administration of HC067047 (10 mg/kg, i.p.) significantly ameliorated SCP-induced cognitive dysfunction as assessed by the novel place recognition test (NPRT) and novel object recognition test (NORT). In the Y-maze test, HC067047 significantly enhanced the time spent in the novel arm in SCP mice. To further investigate the molecular mechanisms underlying the neuroprotective effect of HC067047, expression of several proteins involved in apoptosis was examined. The results demonstrated that HC067047 treatment decreased the protein levels of proapoptotic proteins such as Bax and caspase-3 in the hippocampus of SCP mice. In addition, HC067047 enhanced expression of the neurogenesis marker DCX and improved levels of the mature neuronal marker NeuN in SCP mice. These findings suggest the neuroprotective potential of the TRPV4 inhibitor HC067047 for the management of dementia with learning and memory loss.
作者机构：
[Fouda, Amr; Eid, Ahmed M.; Hassan, Saad El-Din; Abdel-Rahman, Mohamed Ali] Al Azhar Univ, Fac Sci, Dept Bot & Microbiol, Cairo 11884, Egypt.;[Hamza, Mohammed F.] Nucl Mat Author, POB 530, Cairo 11728, Egypt.;[Hamza, Mohammed F.] Univ South China, Sch Nucl Sci & Technol, Hengyang 421001, Peoples R China.
通讯机构：
[Fouda, Amr] D;Department of Botany and Microbiology, Faculty of Science, Al-Azhar University, Nasr City, 11884, Cairo, Egypt.
摘要：
Selenium nanoparticles (Se-NPs) has recently received great attention over owing to their superior optical properties and wide biological and biomedical applications. Herein, crystallographic and dispersed spherical Se-NPs were green synthesized using endophytic fungal strain, Penicillium crustosum EP-1. The antimicrobial, anticancer, and catalytic activities of biosynthesized Se-NPs were investigated under dark and light (using Halogen tungsten lamp, 100 Watt, lambda > 420 nm, and light intensity of 2.87W m(-2)) conditions. The effect of Se-NPs was dose dependent and higher activities against Gram-positive and Gram-negative bacteria as well different Candida spp. were attained in the presence of light than obtained under dark conditions. Moreover, the viabilities of two cancer cells (T47D and HepG2) were highly decreased from 95.8 +/- 2.9% and 93.4 +/- 3.2% in dark than those of 84.8 +/- 2.9% and 46.4 +/- 3.3% under light-irradiation conditions, respectively. Significant decreases in IC 50 values of Se-NPs against T47D and HepG2 were obtained at 109.1 +/- 3.8 and 70.4 +/- 2.5 mu g mL(-1), respectively in dark conditions than 19.7 +/- 7.2 and 4.8 +/- 4.2 mu g mL(-1), respectively after exposure to light-irradiation. The photoluminescence activity of Se-NPs revealed methylene blue degradation efficiency of 89.1 +/- 2.1% after 210 min under UV-irradiation compared to 59.7 +/- 0.2% and 68.1 +/- 1.03% in dark and light conditions, respectively. Moreover, superior stability and efficient MB degradation efficiency were successfully achieved for at least five cycles.
通讯机构：
[Zhuoran Liu; Yafeng Xie] D;Department of Clinical Laboratory, The Second Affiliated Hospital of University of South China , Hengyang 421001 , China
摘要：
The outer membrane proteins (OMPs) of Treponema pallidum subsp. pallidum (T. pallidum), the etiological agent of the sexually transmitted disease syphilis, have long been a hot research topic. Despite many hurdles to studying the pathogen, especially the inability to manipulate T. pallidum in vitro genetically, considerable progress has been made in elucidating the structure, pathogenesis and functions of T. pallidum OMPs. In this review, we integrate this information to garner fresh insights into the role of OMPs in the diagnosis, pathogenicity and vaccine development of T. pallidum. Collectively, the essential scientific discussions herein should provide a framework for understanding the current status and prospects of T. pallidum OMPs.
期刊：
Expert Review of Gastroenterology & Hepatology,2022年16(8):753-765 ISSN：1747-4124
通讯作者：
Xiaoyan Yang
作者机构：
[Zhang, Taolan; Yang, Xiaoyan; Hu, Haihong; Deng, Meina; Deng, Huiling; Wu, Yiwen] Univ South China, Hengyang Med Coll, Sch Pharm, Hengyang, Hunan, Peoples R China.;[Zhang, Taolan] Univ South China, Hengyang Med Sch, Affiliated Hosp 1, Pharm Dept, Hengyang, Hunan, Peoples R China.;[Yang, Xiaoyan] Univ South China, Hunan Prov Key Lab Tumor Microenvironm Respons Dr, Hengyang, Hunan, Peoples R China.
通讯机构：
[Xiaoyan Yang] S;School of Pharmacy, Hengyang Medical College, University of South China, Hengyang, Hunan, China<&wdkj&>The Hunan Provincial Key Laboratory of Tumor Microenvironment Responsive Drug Research, University of South China, Hengyang, Hunan, China
摘要：
In order to remove and recover uranium from acidic uranium-bearing wastewater in uranium mining and metallurgy. Herein, a novel chitosan/Chlorella pyrenoidosa composite adsorbent bearing phosphate ligand (CSP/CP) was designed and synthesized, demonstrating a high uranium adsorption capacity at a pH of 5 and excellent selectivity in an aqueous solution with eight coexisting ions. The CSP/CP exhibits a maximum adsorption capacity (1393.338mgg(-1)) and selectivity (Su=80.53%) for uranium, which is higher than many reported adsorbents. Mechanism analysis shows that the surface of CSP/CP is rich in hydroxyl, amino, phosphate and carboxyl groups, resulting in an excellent three-dimensional structure with active sites for high-performance uranium adsorption; U(VI) is selectively bound via ion exchanges with -COOH and -OH and through surface complexation with NH(2) and PO. Furthermore, by desorption with 0.1M Na(2)CO(3) + 2% H(2)O(2) at 318K, CSP/CP can be recycled more than five times. It provides a new scientific basis for the preparation of high selectivity composite adsorbent by chitosan.
期刊：
Journal of Molecular Medicine,2022年100(11):1511-1538 ISSN：0946-2716
通讯作者：
Junfa Zeng<&wdkj&>Anbo Gao
作者机构：
[Xiao, Hong; Zeng, Junfa] Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Dept Crit Care Med, Hengyang 421002, Hunan, Peoples R China.;[Zhou, Hong] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Radiol, Hengyang 421002, Hunan, Peoples R China.;[Zeng, Gaofeng] Univ South China, Affiliated Hosp 2, Hengyang Med Sch,Key Lab Heart Failure Prevent &, Dept Cardiovasc Med,Clin Med Res Ctr Arterioscler, Hengyang 421002, Hunan, Peoples R China.;[Mao, Zhenjiang] Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Dept Gastroenterol, Hengyang 421002, Hunan, Peoples R China.;[Gao, Anbo] Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Clin Res Inst, Hengyang 421002, Hunan, Peoples R China.
通讯机构：
[Junfa Zeng] D;[Anbo Gao] C;Department of Critical Care Medicine, Hengyang Medical School, The Second Affiliated Hospital, University of South China, Hunan, China<&wdkj&>Clinical Research Institute, Hengyang Medical School, The Second Affiliated Hospital, University of South China, Hunan, China
摘要：
Small ubiquitin-like modifier (SUMO) plays a key regulatory role in cardiovascular diseases, such as cardiac hypertrophy, hypertension, atherosclerosis, and cardiac ischemia-reperfusion injury. As a multifunctional posttranslational modification molecule in eukaryotic cells, SUMOylation is essentially associated with the regulation of mitochondrial dynamics, especially mitophagy, which is involved in the progression and development of cardiovascular diseases. SUMOylation targeting mitochondrial-associated proteins is admittedly considered to regulate mitophagy activation and mitochondrial functions and dynamics, including mitochondrial fusion and fission. SUMOylation triggers mitochondrial fusion to promote mitochondrial dysfunction by modifying Fis1, OPA1, MFN1/2, and DRP1. The interaction between SUMO and DRP1 induces SUMOylation and inhibits lysosomal degradation of DRP1, which is further involved in the regulation of mitochondrial fission. Both SUMOylation and deSUMOylation contribute to the initiation and activation of mitophagy by regulating the conjugation of MFN1/2 SERCA2a, HIF1α, and PINK1. SUMOylation mediated by the SUMO molecule has attracted much attention due to its dual roles in the development of cardiovascular diseases. In this review, we systemically summarize the current understanding underlying the expression, regulation, and structure of SUMO molecules; explore the biochemical functions of SUMOylation in the initiation and activation of mitophagy; discuss the biological roles and mechanisms of SUMOylation in cardiovascular diseases; and further provide a wider explanation of SUMOylation and deSUMOylation research to provide a possible therapeutic strategy for cardiovascular diseases. Considering the precise functions and exact mechanisms of SUMOylation in mitochondrial dysfunction and mitophagy will provide evidence for future experimental research and may serve as an effective approach in the development of novel therapeutic strategies for cardiovascular diseases. Regulation and effect of SUMOylation in cardiovascular diseases via mitophagy. SUMOylation is involved in multiple cardiovascular diseases, including cardiac hypertrophy, hypertension, atherosclerosis, and cardiac ischemia-reperfusion injury. Since it is expressed in multiple cells associated with cardiovascular disease, SUMOylation can be regulated by numerous ligases, including the SENP family proteins PIAS1, PIASy/4, UBC9, and MAPL. SUMOylation regulates the activation and degradation of PINK1, SERCA2a, PPARγ, ERK5, and DRP1 to mediate mitochondrial dynamics, especially mitophagy activation. Mitophagy activation regulated by SUMOylation further promotes or inhibits ventricular diastolic dysfunction, perfusion injury, ventricular remodelling and ventricular noncompaction, which contribute to the development of cardiovascular diseases.
摘要：
Purpose: This study aimed to evaluate whether high-energy X-rays (HEXs) of the PARTER (platform for advanced radiotherapy research) platform built on CTFEL (Chengdu THz Free Electron Laser facility) can produce ultrahigh dose rate (FLASH) X-rays and trigger the FLASH effect. Materials and methods: EBT3 radiochromic film and fast current transformer (FCT) devices were used to measure absolute dose and pulsed beam current of HEXs. Subcutaneous tumor-bearing mice and healthy mice were treated with sham, FLASH, and conventional dose rate radiotherapy (CONV), respectively to observe the tumor control efficiency and normal tissue damage. Results: The maximum dose rate of HEXs of PARTER was up to over 1000 Gy/s. Tumor-bearing mice experiment showed a good result on tumor control (p < 0.0001) and significant difference in survival curves (p < 0.005) among the three groups. In the thorax-irradiated healthy mice experiment, there was a significant difference (p = 0.038) in survival among the three groups, with the risk of death decreased by 81% in the FLASH group compared to that in the CONV group. The survival time of healthy mice irradiated in the abdomen in the FLASH group was undoubtedly higher (62.5% of mice were still alive when we stopped observation) than that in the CONV group (7 days). Conclusion: This study confirmed that HEXs of the PARTER system can produce ultrahigh dose rate X-rays and trigger a FLASH effect, which provides a basis for future scientific research and clinical application of HEX in FLASH radiotherapy. (C) 2021 The Authors. Published by Elsevier B.V.
作者：
Ablikim, M.;Achasov, M. N.;Adlarson, P.;Ahmed, S.;Albrecht, M.;...
期刊：
PHYSICAL REVIEW D,2022年106(7) ISSN：2470-0010
作者机构：
[Yu, B. X.; Yu, G.; Hu, T.; Ning, Z.; Lavezzi, L.; Wen, S. P.; Shi, X.; Sun, G. X.; Ma, M. M.; Zhao, Ling; Zhu, Z. A.; Xu, G. F.; Wang, K.; Zhou, L. P.; Heng, Y. K.; Ji, Q.; Zhang, J. W.; Rong, G.; Guan, C. Y.; Zhou, Q.; Wang, Y. F.; Wang, L. L.; Lu, Y.; Ouyang, Q.; Ji, X. B.; Qian, S.; Dong, M. Y.; Zhang, Jiawei; Fang, S. S.; Chang, J. F.; Wang, Zongyuan; Liu, Z. A.; Ke, B. C.; Wu, J. F.; Sun, S. S.; Fu, C. D.; Lou, X. C.; Zhang, B. X.; Xing, T. Y.; Cao, G. F.; Xiao, Y. J.; Wu, L. H.; Zhao, Y. B.; Zheng, J. P.; Jiang, X. S.; Kiuchi, R.; Gu, M. H.; Lu, Y. P.; Dong, L. Y.; Yang, S. L.; Zhao, G.; Wu, L. J.; Yang, Yifan; Yuan, Y.; Lu, X. L.; Wu, Z.; Fang, Y.; Luo, X. L.; Ji, X. L.; Zhu, A. N.; Li, L. K.; Li, H. B.; Liang, H.; Liao, L. Z.; Zhang, J. Y.; Yin, J. H.; Liu, Huanhuan; Zhang, J. Z.; He, K. L.; Chen, G.; Xiong, X. A.; Ablikim, M.; Liu, C. X.; Chang, W. L.; Zhu, K.; Kurth, M. G.; Zhao, J. Z.; Mao, Z. P.; Zhao, Q.; Xiao, S. Y.; Lu, J. G.; Chen, Y. B.; Wang, Z.; Gao, H.; Liu, Fang; Zhao, J. Y.; Liu, K.; Wang, H. P.; Yuan, C. Z.; Tang, G. Y.; Zhang, H. Y.; Chen, M. L.; Hou, Z. L.; Sun, Y. Z.; Liu, B. J.; Li, Ke; Zhu, K. J.; Liu, H. M.; Ma, H. L.; Sun, T.; Ye, M.; Xie, Y. G.; Lu, J. D.; Zou, B. S.; Chen, H. S.; Cao, N.; Deng, Z. Y.; Ma, Q. M.; Wang, Z. Y.; Cai, X.; Zhang, Y. H.; Ma, R. Q.; Shi, R. S.; Zou, J. H.; Zhang, Yao; Liu, J. Y.; Li, W. G.; Wang, Y. Q.; Mo, X. H.; Fang, J.; Ma, X. X.; Shen, X. Y.; Sun, Z. T.; Liu, T.; Ma, X. Y.; Hu, H. M.; Gong, W. X.; Xu, W.; Hu, Y.; Wang, B.; Wang, Meng; Zhang, L.; Zhang, Jianyu; Li, F.; Pathak, A.; Yang, H. X.; Qin, Z. H.; Li, G.; Ping, R. G.; Qiu, J. F.; Dai, H. L.; Li, W. D.] Inst High Energy Phys, Beijing 100049, Peoples R China.;[Gu, Y. T.; Shen, C. P.; Qi, T. Y.] Beihang Univ, Beijing 100191, Peoples R China.;[Li, Lei] Beijing Inst Petrochem Technol, Beijing 102617, Peoples R China.;[Jaeger, S.; Fritsch, M.; Heinsius, F. H.; Zhang, J. Q.; Weber, T.; Kuessner, M.; Pitka, A.; Pelizaeus, M.; Kopf, B.; Keshk, I. K.; Wollenberg, L.; Qin, X. S.; Albrecht, M.; Holtmann, T.; Schnier, C.; de Boer, R. E.; Feldbauer, F.; Wiedner, U.; Kuemmel, M.; Li, J. Q.; Held, T.] Bochum Ruhr Univ, D-44780 Bochum, Germany.;[Briere, R. A.] Carnegie Mellon Univ, Pittsburgh, PA 15213 USA.
摘要：
A search for a massless dark photon gamma' is conducted using 4.5 fb(-1) of e(+)e(-) collision data collected at center-of-mass energies between 4.600 and 4.699 GeV with the BESIII detector at BEPCII. No significant signal is observed, and the upper limit on the branching fraction B(Lambda(+)(c) -> p gamma') is determined to be 8.0 x 10(-5) at 90% confidence level.
