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Cross-regulation between microRNAs and key proteins of signaling pathways in hepatocellular carcinoma

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成果类型:
期刊论文
作者:
Hu, Haihong;Zhang, Taolan;Wu, Yiwen;Deng, Meina;Deng, Huiling;...
通讯作者:
Xiaoyan Yang
作者机构:
[Zhang, Taolan; Yang, Xiaoyan; Hu, Haihong; Deng, Meina; Deng, Huiling; Wu, Yiwen] Univ South China, Hengyang Med Coll, Sch Pharm, Hengyang, Hunan, Peoples R China.
[Zhang, Taolan] Univ South China, Hengyang Med Sch, Affiliated Hosp 1, Pharm Dept, Hengyang, Hunan, Peoples R China.
[Yang, Xiaoyan] Univ South China, Hunan Prov Key Lab Tumor Microenvironm Respons Dr, Hengyang, Hunan, Peoples R China.
通讯机构:
[Xiaoyan Yang] S
School of Pharmacy, Hengyang Medical College, University of South China, Hengyang, Hunan, China<&wdkj&>The Hunan Provincial Key Laboratory of Tumor Microenvironment Responsive Drug Research, University of South China, Hengyang, Hunan, China
语种:
英文
关键词:
MicroRNAs;hepatocellular carcinoma;signaling pathway;interaction;target
期刊:
Expert Review of Gastroenterology & Hepatology
ISSN:
1747-4124
年:
2022
卷:
16
期:
8
页码:
753-765
基金类别:
The present study was supported from National Natural Science Foundation of China (grant number 82003802), the Natural Science Foundation of Hunan Province (grant number 2019JJ50542), the Science and Technology program of Hunan Health Commission (grant number 20201978), the China Scholarship Council (grant no. 201808430085), the Scientific Research Project of Hunan Provincial Education Department(grant number 21B0438), the Hengyang City Science and Technology Planning Project (grant number 202150063473), the Scientific Research Project of Hunan Provincial Health Commission (grant number 202202044140), the Undergraduate Research based Learning and Innovative Experimental Program of Hunan Province (grant number S202112650003 and S202112650005).
机构署名:
本校为第一机构
院系归属:
药学与生物科学学院
摘要:
Introduction: Hepatocellular carcinoma (HCC) is a subtype of primary liver cancer and a major cause of death. Although miRNA plays an important role in hepatocellular carcinoma, the specific regulatory network remains unclear. Therefore, this paper comprehensively describes the miRNA-related signaling pathways in HCC and the possible interactions among different signaling pathways. The aim is to lay the foundation for the discovery of new molecular targets and multi-target therapy. Areas covered: Based on miRNA, HCC, and signaling pathways, the...

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