摘要：
Considering great threats of nitrite in food toward public health, it is significant to develop portable, dependable, and cost-effective methods to detect the target. In comparison with traditional colorimetric or fluorometric strategies relying on the intensity variation at a single wavelength, multimodal measurement with notable color changes is a more attractive paradigm because of its stronger resistance against external conditions, expanded application scenario, improved reliability, and naked-eye distinguishable readouts. However, it remains a challenge on how to attain this goal. Here we proposed a smartphone-integrated paper sensor based on manganese-doped silicon quantum dots (Mn-SiQDs) for the visual dual-mode multicolor/multifluorescence determination of nitrite. The Mn-SiQDs featured both photoluminescence and oxidase-mimetic catalytic activity, and could stimulate the colorless 3,3',5,5' -tetramethylbenzidine (TMB) oxidation to a blue species TMB+. When nitrite existed, the generated TMB+ selectively reacted with the analyte to produce yellow diazotized TMB+. Meanwhile, the photoluminescence of Mn-SiQDs could be suppressed by the diazotized TMB+ via inner filter effect. As a result, with a facile electrostatic assembly of Mn-SiQDs and [Ru(bpy)(3)](2+), the formed complex MnSiQDs/[Ru(bpy)(3)](2+) led to the variations of both color and photoluminescence upon different levels of nitrite. By combining the principle with paper strips and smartphone sensing, the fabricated sensor offered naked-eye visible multicolor/multifluorescence dual-mode response toward nitrite, exhibiting excellent specificity, performance stability, and practicability in food analysis. Our work provides an effective tool to achieve the multicolor/multifluorescence bimodal measurement of nitrite, and it will inspire future effort on designing versatile materials for advanced sensing applications.
摘要：
With the attractive advantage of catalytic signal amplification, noble metal-based peroxidase-mimicking nano -materials have been intensively used to establish optical methods for hypertoxic Hg2+ detection. However, in these methods the requirement of high-concentration H2O2 can lead to secondary pollution, and the noble metals used result in these assays' high cost. Therefore, exploring new categories of enzyme mimics to develop envi-ronmentally friendly and low-cost approaches for Hg2+ sensing is highly desired. Herein we proposed a novel noble metal-free material, MnSe microparticles, featuring specific Hg2+-suppressed oxidase-like catalytic activ-ity, to fabricate a green, cheap, and high-performance turn-off approach for Hg2+ detection. The MnSe micro -particles with a polyhedral structure were obtained via a one-pot solvothermal process, showing excellent oxidase-like activity to catalyze the oxidation of colorless 3,3 ',5,5 '-tetramethylbenzidine (TMB) to its blue product. The introduction of Hg2+ can significantly mask their active sites via forming an inert layer of HgSe outside the MnSe microparticles, thus suppressing the TMB catalytic color reaction. Based on the turn-off principle, colorimetric quantification of Hg2+ was realized with high sensitivity and specificity. By integrating smartphone sensing with 3D-printed accessories and paper strips, a portable platform for the convenient detection of Hg2+ was further established, demonstrating its great practicability in real analysis.
期刊：
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY,2023年13:1179369 ISSN：2235-2988
通讯作者：
Li, Dan;Tang, SY;Li, D
作者机构：
[Li, Dan; Tang, Si-Yuan; Li, D] Cent South Univ, Xiangya Sch Nursing, Changsha, Hunan, Peoples R China.;[Li, D; Li, Dan] Hunan Open Univ, Coll Appl Technol, Changsha, Hunan, Peoples R China.;[Lei, Sheng] Hunan Chest Hosp, Intervent Radiol Ctr, Changsha, Hunan, Peoples R China.;[Xie, He-Bin] Univ South China, Changsha Cent Hosp, Dept Drug Clin Trial Inst, Hengyang Med Sch, Changsha, Hunan, Peoples R China.;[Li, Lin-Qi] Univ South China, Sch Publ Hlth, Hengyang, Peoples R China.
通讯机构：
[Li, D ] H;[Tang, SY ; Li, D] C;Cent South Univ, Xiangya Sch Nursing, Changsha, Hunan, Peoples R China.;Hunan Open Univ, Coll Appl Technol, Changsha, Hunan, Peoples R China.
作者：
Du, Zhongye;Han, Jiahui;Luo, Jing;Bi, Guan;Liu, Tangjuan;...
期刊：
NEW MICROBIOLOGICA,2023年46(3):258-263 ISSN：1121-7138
通讯作者：
Kong, Jinliang;Chen, YQ
作者机构：
[Du, Zhongye; Bi, Guan; Kong, Jinliang; Kong, JL; Chen, Yiqiang; Luo, Jing; Liu, Tangjuan; Chen, YQ] Guangxi Med Univ, Affiliated Hosp 1, Dept Pulm & Crit Care Med, Nanning, Peoples R China.;[Han, Jiahui] Guangxi Med Univ, Affiliated Hosp 2, Dept Intens Care Unit, Nanning, Peoples R China.;[Han, Jiahui] Univ South China, Hengyang Med Sch, Sch Publ Hlth, Basic Med Sci, Hengyang, Peoples R China.
通讯机构：
[Kong, JL; Chen, YQ ] G;Guangxi Med Univ, Affiliated Hosp 1, Dept Pulm & Crit Care Med, Nanning, Peoples R China.
关键词：
Staphylococcus aureus;baicalin;linezolid
摘要：
Staphylococcus aureus is a gram-positive bacterium that can produce biofilm, and biofilm-associated infections are difficult to control. Biofilm prevents antibiotics from penetrating and killing the bacteria. Combined use of antimicrobials is a common strategy to treat S. aureus biofilm-related infections. In this in vivo study, the clinically isolated strain of S. aureus 17546 (t037) was selected to establish a biofilm-associated infection rat model, and baicalin and linezolid were used to treat the infection. CFU counting was used to determine the bacteria within the biofilm, the biofilm structure was viewed using scanning electron microscopy (SEM), histopathology was performed, and inflammatory factors were analyzed by ELISA. Baicalin was efficient in destroying the biofilm and exerted a synergistic bactericidal effect when combined with linezolid. Based on these findings, baicalin combined with linezolid may be efficacious in controlling S. aureus biofilm-related infections.
期刊：
Sensors and Actuators B-Chemical,2022年370:132451 ISSN：0925-4005
通讯作者：
Xiangheng Niu
作者机构：
[Pan, Jianming; Liu, Bangxiang; Hu, Panwang; Wang, Mengzhu; Niu, Xiangheng; Zhu, Hengjia] Jiangsu Univ, Inst Green Chem & Chem Technol, Sch Chem & Chem Engn, Zhenjiang 212013, Peoples R China.;[Feng, Rulin] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China.;[Niu, Xiangheng] Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hengyang 421001, Peoples R China.
通讯机构：
[Xiangheng Niu] I;Institute of Green Chemistry and Chemical Technology, School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, China<&wdkj&>School of Public Health, Hengyang Medical School, University of South China, Hengyang 421001, China
关键词：
Molecularly imprinted nanozyme;Tetracycline;Colorimetric assay;Catalytic signal amplification;Selective sensing
期刊：
NEW JOURNAL OF CHEMISTRY,2022年46(10):4806-4813 ISSN：1144-0546
通讯作者：
Cai, QY;Zhen, DS
作者机构：
[Cai, Qingyun; Song, Jie; Tan, Wenlong; Sun, Leilei; Cai, QY; Geng, Hongchao] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Peoples R China.;[Zhen, Deshuai] Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hunan Prov Key Lab Typ Environm Pollut & Hlth Haz, Hengyang 421001, Peoples R China.
通讯机构：
[Zhen, DS ] U;[Cai, QY ] H;Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Peoples R China.;Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hunan Prov Key Lab Typ Environm Pollut & Hlth Haz, Hengyang 421001, Peoples R China.
摘要：
beta-Phase NaYF4:Yb,Tm,Gd up-conversion nanorods (UCNRs) with high uniformity were synthesized by a solvothermal method. The optimal fluorescence intensity of UCNRs was explored. After further modification with Materials of Institute Lavoisier-100(Fe) (MIL-100(Fe)) by the layer-by-layer self-assembly method, near-infrared light-triggered UCNR@MIL-100(Fe) nanomaterials with excellent antibacterial performances were constructed. A core-shell structure was constructed and confirmed by transmission electron microscopy (TEM). Reactive oxidizing species (ROS) detection indicated that the nanomaterials owned good photodynamic efficacy. The antibacterial experiments showed that the nanomaterials with 980 nm light irradiation and hydrogen peroxide (H2O2) had good antibacterial activity against Gram-negative and Gram-positive bacteria. Under 980 nm laser excitation, UCNRs generated ultraviolet and visible light to activate MIL-100(Fe) and induced a photo-Fenton reaction, which further produced oxygen species for antibacterial applications.
作者：
Liu, Haohao;Zeng, Xin;Wang, Yueqin;Losiewicz, Michael D.;Chen, Xinghai;...
期刊：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2022年70(35):10907-10918 ISSN：0021-8561
通讯作者：
Fei Yang<&wdkj&>Huizhen Zhang
作者机构：
[Liu, Haohao; Wang, Yongshui; Guo, Xing; Zhang, Huizhen; Zeng, Xin; Du, Xingde; Yuan, Shumeng; Wang, Yueqin; Zhang, Bingyu] Zhengzhou Univ, Coll Publ Hlth, Zhengzhou 450001, Henan, Peoples R China.;[Yang, Fei] Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hunan Prov Key Lab Typ Environm Pollut & Hlth Haza, Hengyang 421001, Hunan, Peoples R China.;[Yang, Fei] Cent South Univ, Xiangya Sch Publ Hlth, Hunan Prov Key Lab Clin Epidemiol, Changsha 410008, Hunan, Peoples R China.;[Chen, Xinghai; Losiewicz, Michael D.] St Marys Univ, Dept Chem & Biochem, San Antonio, TX 78228 USA.
通讯机构：
[Fei Yang] H;[Huizhen Zhang] C;Hunan Province Key Laboratory of Typical Environmental Pollution and Health Hazards, School of Public Health, Hengyang Medical School, University of South China, Hengyang421001, Hunan, China<&wdkj&>Hunan Provincial Key Laboratory of Clinical Epidemiology, Xiangya School of Public Health, Central South University, Changsha410008, Hunan, China<&wdkj&>College of Public Health, Zhengzhou University, Zhengzhou450001, Henan, China
摘要：
Microcystin-leucine arginine (MC-LR), ubiquitous in water and food, is a threat to public health. In the present study, after C57BL/6J mice were fed with environmental concentrations of MC-LR (0, 1, 30, 60, 90, and 120 μg/L) for 6, 9, and 12 months, it was found that MC-LR could enter into mouse lung tissues and cause microstructural damage, as shown by western blotting and HE staining. Electron microscopy examination showed that MC-LR could damage the lung barrier by disruption of the tight junctions, which was confirmed by the decreased expression of tight junction markers, including Occludin, Claudin1, and ZO-1. In addition, MC-LR also increased the ubiquitination of Claudin1, indicating that MC-LR could disrupt tight junctions by promoting the degradation of Claudin1. Furthermore, MC-LR increased the levels of TNF-α and IL-6 in mouse lung tissues, leading to pneumonia. Importantly, pretreatment with PP2A activator D-erythro-sphingosine (DES) was found to significantly alleviate MC-LR-induced decrease of Occludin and Claudin1 by inhibiting the P-AKT/Snail pathway in vitro. Together, this study revealed that chronic exposure to MC-LR causes lung barrier damage, which involves PP2A activity inhibition and enhancement of Claudin1 ubiquitination. This study broadens the awareness of the toxic effects of MC-LR on the respiratory system, which has deep implications for public health.
通讯机构：
[Huai-Cai Zeng] D;Department of Environmental and Occupational Health, School of Public Health, Guilin Medical University, Guilin 541199, China<&wdkj&>Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Health, Guilin Medical University, Guilin 541199, China<&wdkj&>Guangxi Health Commission Key Laboratory of Entire Lifecycle Health and Care, Guilin Medical University, Guilin 541199, China<&wdkj&>Author to whom correspondence should be addressed.
摘要：
Bisphenol S (BPS), the most common substitute for bisphenol A in manufacturing, is associated with neurotoxicity, but its molecular mechanisms are unclear. Here, we studied the role of the BDNF-TrkB-CREB (brain-derived neurotrophic factor-tropomyosin-related kinase B-CAMP response element-binding protein) signalling pathway in bisphenol S-induced neurotoxicity via methylation regulation in male C57BL/6 mice. The mice were treated with sesame oil or 2, 20 and 200 mg/kg body weight BPS for 28 consecutive days, and the hippocampus was extracted. We recorded the body weight, organ index, and hippocampal pathology and ultrastructure of the mice. The BDNF, TrkB, CREB, phosphorylated (p)-CREB, DNMTs (DNA methyltransferases) levels were determined by qRT-PCR and/or Western blotting. BDNF promoter IV methylation level was detected by bisulfite sequencing PCR. BPS damaged the mouse hippocampus ultrastructure and reduced the number of synapses. Further, it increased the methylation rate of BDNF promoter IV; downregulated BDNF, CREB, p-CREB/CREB and DNMT1 expression; and upregulated DNMT3a and DNMT3b expression. Therefore, we speculate that the BDNF-TrkB-CREB pathway may be involved in BPS-induced neurotoxicity in male mice by regulating methylation.
作者机构：
[Cao, Yi] Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hunan Prov Key Lab Typ Environm Pollut & Hlth Haz, Hengyang 421001, Peoples R China.
通讯机构：
[Cao, Yi] H;Hunan Province Key Laboratory of Typical Environmental Pollution and Health Hazards, School of Public Health, Hengyang Medical School, University of South China, Hengyang 421001, China. Electronic address:
摘要：
Ionizing radiation (IR) can induce pulmonary fibrosis by causing epithelial mesenchymal transition (EMT), but the exact mechanism has not been elucidated. To investigate the molecular mechanism of how radiation induces pulmonary fibrosis by altering miR-486-3p content and thus inducing EMT. The changes of miR-486-3p in cells after irradiation were detected by RT-qPCR. Western blot was used to detect the changes of cellular epithelial marker protein E-cadherin, mesenchymal marker N-cadherin, Vimentin and other proteins. The target gene of miR-486-3p was predicted by bioinformatics method and the binding site was verified by dual luciferase reporter system. In vivo experiments, adeno-associated virus (AAV) was used to carry miR-486-3p mimic to lung. Radiation-induced pulmonary fibrosis (RIPF) model was constructed by 25Gy60Co γ-rays. The structural changes of mouse lung were observed by HE and Masson staining. The expression of relevant proteins in mice was detected by immunohistochemistry. IR could decrease the miR-486-3p levels in vitro and in vivo, and that effect was closely correlated to the occurrence of RIPF. The expression of Snail, which induces EMT, was shown to be restrained by miR-486-3p. Therefore, knockdown of Snail blocked the EMT process induced by radiation or knockdown of miR-486-3p. In addition, the molecular mechanism underlying the IR-induced miRNA level reduction was explored. The increased in BCL6 could inhibit the formation of pri-miR-486-3p, thereby reducing the levels of miR-486-3p in the alveolar epithelial cells, which would otherwise promote EMT and contribute to RIPF by targeting Snail. IR can exacerbate RIPF in mice by activating the transcription factor BCL6, which inhibits the transcription of miR-486-3p and decreases its content, which in turn increases the content of the target gene slug and triggers EMT.
通讯机构：
[Hua Guan; Chen-Jun Bai] D;[Ping-Kun Zhou] C;Department of Radiation Biology, Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, People’s Republic of China<&wdkj&>Department of Radiation Biology, Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, People’s Republic of China<&wdkj&>College of Public Health, Hengyang Medical School, University of South China, Hengyang, People’s Republic of China<&wdkj&>Department of Radiation Biology, Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, People’s Republic of China
关键词：
LPAR5;ERK;Radioresistance;EMT;Radiotherapy
摘要：
BACKGROUND: Epithelial-to-mesenchymal transition (EMT) is a critical event contributing to more aggressive phenotypes in cancer cells. EMT is frequently activated in radiation-targeted cells during the course of radiotherapy, which often endows cancers with acquired radioresistance. However, the upstream molecules driving the signaling pathways of radiation-induced EMT have not been fully delineated. METHODS: In this study, RNA-seq-based transcriptome analysis was performed to identify the early responsive genes of HeLa cells to γ-ray irradiation. EMT-associated genes were knocked down by siRNA technology or overexpressed in HeLa cells and A549 cells, and the resulting changes in phenotypes of EMT and radiosensitivity were assessed using qPCR and Western blotting analyses, migration assays, colony-forming ability and apoptosis of flow cytometer assays. RESULTS: Through RNA-seq-based transcriptome analysis, we found that LPAR5 is downregulated in the early response of HeLa cells to γ-ray irradiation. Radiation-induced alterations in LPAR5 expression were further revealed to be a bidirectional dynamic process in HeLa and A549 cells, i.e., the early downregulating phase at 2 ~ 4h and the late upregulating phase at 24h post-irradiation. Overexpression of LPAR5 prompts EMT programing and migration of cancer cells. Moreover, increased expression of LPAR5 is significantly associated with IR-induced EMT and confers radioresistance to cancer cells. Knockdown of LPAR5 suppressed IR-induced EMT by attenuating the activation of ERK signaling and downstream Snail, MMP1, and MMP9 expression. CONCLUSIONS: LPAR5 is an important upstream regulator of IR-induced EMT that modulates the ERK/Snail pathway. This study provides further insights into understanding the mechanism of radiation-induced EMT and identifies promising targets for improving the effectiveness of cancer radiation therapy.
通讯机构：
[Yang, Shengyuan] U;[Yang, Shengyuan] H;Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.;Hunan Key Lab Typ Environm Pollut & Hlth Hazards, Hengyang 421001, Hunan, Peoples R China.
摘要：
Nitrogen and sulfur co-doped carbon dots (N,S-CDs) with strong orange fluorescence were fabricated through a facile hydrothermal method using o-phenylenediamine and thiourea as precursors. The N,S-CDs exhibited excitation-independent photoluminescent behavior with excellent stability. The largest emission peak at 565 nm occurred at an excitation wavelength of 420 nm, and the quantum yield (QY) was 14.3%. It was found that the absorption spectra of vitamin B-12 (VB12) overlaps with the emission peak of the N,S-CDs to a large extent, and based on the inner filter effect (IFE) between VB12 and N,S-CDs, a label-free and sensitive detection method of VB12 in drugs was established. Under optimal conditions, the concentration of VB12 exhibited a satisfactory linear correlation with the fluorescence quenching degree Delta F/F-0 of the reaction system at 565 nm in the range of 0.25-20 mu M, and the detection limit was 77.5 nM. The N,S-CDs with orange fluorescence emission show huge potential for use in the field of biological analysis.
通讯机构：
[Shuxia Xing] I;[Dingxin Long] S;Institute for Food and Cosmetics Control, National Institutes for Food and Drug Control, Beijing, China<&wdkj&>School of Public Health, University of South China, Hengyang, China
摘要：
With the growth of the aging population, the prevalence of Alzheimer's disease (AD) has increased and influenced the work and daily life of AD patients, imposing a heavy burden on society and the patients' families. AD is a progressive disease with a long duration, and the pathogenesis is very complicated. Here, we found that alpha-lipoic acid (LA), an endogenous, naturally synthesized compound, could attenuate amyloid beta fragment (A beta(25-35))-induced PC12 cell toxicity. A beta(25-35) treatment largely decreased the viability of PC12 cells, increased reactive oxygen species (ROS) levels, and increased the percentage of apoptotic cells, which were accompanied by changes in the expression of the apoptosis-related genes. Further, the Wnt pathway was inactivated, and the expression of Wnt pathway-related proteins such as Frizzled2, GSK3 beta, and phosphorylated GSK3 beta were dysregulated after A beta(25-35) treatment. LA efficiently attenuated A beta(25-35)-induced PC12 cell apoptosis and downregulated the phosphorylation-mediated degradation of beta-catenin as well as GSK3 beta. Our results demonstrate that LA rescues A beta(25-35)-induced neurocytotoxicity through the Wnt-beta-catenin pathway.
期刊：
Journal of Hazardous Materials,2022年440:129793 ISSN：0304-3894
通讯作者：
Fei Yang
作者机构：
[Feng, Xiangling; Chen, Jihua; Liu, Wenya; Yang, Fei; Yang, Yue; Chen, Mengshi] Cent South Univ, Xiangya Sch Publ Hlth, Hunan Prov Key Lab Clin Epidemiol, Changsha, Peoples R China.;[Wang, Hui; Deng, Shuxiang; Chu, Hanyu; Cao, Yi; Liu, Ying; Long, Dingxin; Cai, Danping; Cao, Deliang; Yang, Fei] Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hunan Prov Key Lab Typ Environm Pollut & Hlth Haza, Hengyang, Peoples R China.;[Wang, Xiaoyan] Cent South Univ, Xiangya Hosp 3, Dept Gastroenterol, Changsha, Peoples R China.;[Chen, Ling] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Hengyang, Peoples R China.;[Wang, Chengkun] Univ South China, Sch Basic Med, Hengyang Med Sch, Dept Med Pathol, Hengyang, Peoples R China.
通讯机构：
[Fei Yang] H;Hunan Province Key Laboratory of Typical Environmental Pollution and Health Hazards, School of Public Health, Hengyang Medical School, University of South China, Hengyang, China<&wdkj&>Hunan Provincial Key Laboratory of Clinical Epidemiology, Xiangya School of Public Health, Central South University, Changsha, China<&wdkj&>Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, China
摘要：
Microcystin-LR (MC-LR) is a very common toxic cyanotoxins threating ecosystems and the public health. This study aims to explore the long-term effects and potential toxicity mechanisms of MC-LR exposure at environmental levels on colorectal injury. We performed histopathological, biochemical indicator and multi-omics analyses in mice with low-dose MC-LR exposure for 12 months. Long-term environmental levels of MC-LR exposure caused epithelial barrier disruption, inflammatory cell infiltration and an increase of collagen fibers in mouse colorectum. Integrated proteotranscriptomics revealed differential expression of genes/proteins, including CSF1R, which were mainly involved in oxidative stress-induced premature senescence and inflammatory response. MC-LR induced chronic inflammation and fibrosis through oxidative stress and CSF1R/Rap1b signaling pathway were confirmed in cell models. We found for the first time that long-term environmental levels of MC-LR exposure caused colorectal chronic inflammation, fibrosis and barrier disruption via a novel CSF1R/Rap1b signaling pathway. Moreover, MC-LR changed the gut microbiota and microbial-related metabolites in a vicious cycle aggravating colorectal injury. These findings provide novel insights into the effects and toxic mechanisms of MC-LR and suggest strategies for the prevention and treatment of MC-caused intestinal diseases.
摘要：
Sr-90 is one of the most hazardous contaminants in the environment. In this work, the radioactive level of Sr-90 in soil along the Hai River in Tianjin, China, was detected to investigate the background radioactivity level of Tianjin and assess its hazards to humans and the environment. Twenty-seven soil samples were collected from 12 sampling points along the Hai River. The soil samples were pretreated by microwave digestion and separated by Sr-specific resin. The recovery rate of carrier (Sr-88) was detected by inductively coupled plasma-mass spectrometry (ICP-MS) and the radioactivity of Sr-90 of the samples was detected by a liquid scintillation counter (LSC). The recovery rate of carrier was between 45.83 and 83.38%, and the average recovery rate was 71.58%. The radioactivity concentration of Sr-90 in soil samples ranged from 0.251 to 0.865 Bq/g, and the average radioactivity concentration was 0.419 Bq/g. In addition, the method had a minimum detection limit (MDL) of 0.292 Bq/g, with only one sample below it, and the average error was 0.096. In conclusion, the radioactivity concentration of Sr-90 in the soil along the Hai River was extremely low, and it would hardly affect the human body and the biosphere.
作者机构：
Institute for Environmental Medicine and Radiation Hygiene, School of Public Health, University of South China, Hengyang, People’s Republic of China;[Song, Man; Bai, Chen-Jun; Xie, Da-Fei; Gao, Shan-shan] Department of Radiation Biology, Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, People’s Republic of China;[Ping, Jie] State Key Laboratory of Proteomics, National Center for Protein Sciences, Beijing Institute of Radiation Medicine, Beijing, People’s Republic of China;College of Life Sciences, Hebei University, Baoding, People’s Republic of China;[Yan, Shuang; Lai, Shu-ting] Institute for Environmental Medicine and Radiation Hygiene, School of Public Health, University of South China, Hengyang, People’s Republic of China<&wdkj&>Department of Radiation Biology, Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, People’s Republic of China
通讯机构：
[Shan-shan Gao] D;[Ping-Kun Zhou] I;Department of Radiation Biology, Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, People’s Republic of China<&wdkj&>Institute for Environmental Medicine and Radiation Hygiene, School of Public Health, University of South China, Hengyang, People’s Republic of China<&wdkj&>Department of Radiation Biology, Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, People’s Republic of China<&wdkj&>College of Life Sciences, Hebei University, Baoding, People’s Republic of China
