作者机构：
[Yu, Miao; Guo, Xin; Zhang, Kai] Sichuan Univ, Sch Mech Engn, Chengdu 610065, Peoples R China.;[Yu, Miao; Guo, Xin; Zhang, Kai] Sichuan Univ, Yibin Ind Technol Res Inst, Yibin 644000, Peoples R China.;[Kang, Xiaomin] Univ South China, Sch Mech Engn, Hengyang 421001, Peoples R China.;[Zhang, Song] Moutai Inst, Dept Food Sci & Engn, Renhuai 564502, Guizhou, Peoples R China.;[Qian, Lu; Qian, L] South China Univ Technol, Sch Mat Sci & Engn, Guangzhou 510641, Peoples R China.
通讯机构：
[Zhang, S ] M;[Qian, L ] S;Moutai Inst, Dept Food Sci & Engn, Renhuai 564502, Guizhou, Peoples R China.;South China Univ Technol, Sch Mat Sci & Engn, Guangzhou 510641, Peoples R China.
摘要：
Hyaluronic acid (HA), a vital glycosaminoglycan in living organisms, possesses remarkable mechanical and viscoelastic properties that have garnered significant attention in therapeutic, biomedical, and cosmetic applications. However, a comprehensive picture of the physicochemical and biocharacterization of HA at the single-molecule level remains elusive. In this work, atomic force microscopy (AFM)-based single-molecule force spectroscopy (SMFS) and molecular dynamics (MD) simulation were used to investigate the nanomechanics and water retention properties of HA at the single-molecule level. The present study aims to unravel the intricate details of the influence of molecular structure on HA behavior and shed light on its unique attributes. According to the force measurements, the energy used to stretch a HA chain in water is 8.45 kJ/mol, significantly surpassing that of Curdlan (3.45 kJ/mol) and chitin (2.23 kJ/mol), both of which possess molecular structures partially similar to that of HA. Intriguingly, the strength of the intrachain interaction of HA (5.54 kJ/mol) was considerably weaker compared to Curdlan (11.06 kJ/mol) and chitin (or cellulose, 10.76 kJ/mol). This result indicates that HA exhibits a preference for interacting with water rather than with itself, thereby showing enhanced water affinity. Moreover, the force measurements demonstrated that changing the glycosidic bond from β-(1-3) (Curdlan) or β-(1-4) (chitin or cellulose) to β-(1-3) + β-(1-4) (HA) resulted in polysaccharides displaying improved water affinity and more extended conformation. These conclusions were further verified by molecular dynamics (MD) simulations. Overall, our work sheds new light on the nanomechanics and water retention properties of HA at the single-molecule level, offering valuable insights for future research in this field.
摘要：
Mining can provide abundant resources, but it also causes heavy metal wastewater pollution, which poses a serious threat to aquatic ecosystems. In this study, Cypridopsis vidua was used as the test organism to investigate the single and combined acute toxicity of common heavy metals (such as chromium (Cr) and nickel (Ni)) in mining wastewater. Then, a random forest model (RF model) was used to predict the combined toxicity of chromium and nickel. Single acute toxicity experiments showed that the 96 h-LC(50 )values of the Cr and Ni for Cypridopsis vidua were 0.81 mg/L and 4.3 mg/L, respectively. aCr was more toxic than Ni. Furthermore, the combined acute toxicity experiments demonstrated that the toxicity of Cr-Ni was higher than Ni but lower than Cr. The predicted results of the RF model were highly consistent with the experimental results of the Cr-Ni combined acute toxicity. So, the model has accurate toxicity prediction ability.
作者机构：
[Chen, Nan; Yuan, Tie-chui; Li, Zhi-you] Cent South Univ, State Key Lab Powder Met, Changsha 410083, Peoples R China.;[Teng, Hao; Chen, Long-wei] Univ South China, Coll Mech Engn, Hengyang 421001, Peoples R China.
通讯机构：
[Li, ZY ] C;[Teng, H ] U;Cent South Univ, State Key Lab Powder Met, Changsha 410083, Peoples R China.;Univ South China, Coll Mech Engn, Hengyang 421001, Peoples R China.
摘要：
With high-energy wet ball milling M2 high-speed steel (HSS) powder and ferrovanadium alloy, an in-situ synthesized core-shell MC carbides reinforced M2 HSS was prepared via vacuum sintering. The phase, morphology and composition distribution of the milled composite powders, and the evolution of the sintered microstructure with the temperature and the associated mechanical properties before and after heat treatment were investigated. The ground powders were fully refined into lamellae and aggregates with V-element evenly distributed inside. Almost full densification (similar to 99.2% relative density) of the modified M2 steel was achieved at 1180 degree celsius by supersolidus liquid phase sintering. Near-spherical MC carbides and irregular M6C carbides were dispersed within the HSS matrix, and the MC developed a core-shell structure due to the solidification of the sintering liquid. Both the matrix grains and carbides of the sintered alloy had been refined by heat treatment, reaching satisfactory bending strength of 3580 MPa and hardness of HRC58, and enhancing the scratch resistance significantly.
会议名称：
International Conference on Cyber-Enabled Distributed Computing and Knowledge Discovery (CyberC)
会议时间：
OCT 17-19, 2019
会议地点：
Guilin Univ Elect Technol, Guilin, PEOPLES R CHINA
会议主办单位：
Guilin Univ Elect Technol
会议论文集名称：
International Conference on Cyber-Enabled Distributed Computing and Knowledge Discovery
关键词：
robot;Cyber-Physical Production System;integration
摘要：
Robots are expected to be used in the smart manufacturing and smart factory with the help of information and communication technologies. The increasing and consistent integration of ICTs and robot into the production systems in subsystems and components are needed. The mechatronic systems become cyber-physical systems through additional communication skills and autonomy in behavior on external influences and internally stored settings. Robots are integrated in the Cyber-Physical Production System to realize smart factory and smart manufacturing. In a laboratory environment, innovative logistical systems integrated with robots are built up to apply horizontal and vertical integration into practice for research investigations.
摘要：
Vending machine as one kind of non-store business has been very popular in the developed countries for many years, and so has been China. Unfortunately, there are only very few related researches that have been done for studying consumers how they operate a vending machine by an efficient and convenient way. The main goal of this research is to explore how to apply the wireless location technology and route planning on designing the display panel of the removable vending machine.
会议名称：
19th Annual Conference and 8th International Conference of Chinese Society of Micro/Nano Technology (CSMNT)
会议时间：
OCT 26-29, 2017
会议地点：
Dalian, PEOPLES R CHINA
会议主办单位：
[Hao, R.;Yu, H. J.;Zhou, W.;Peng, B.;Guo, J.] Univ Elect Sci & Technol China, Dept Mechatron Engn, Ctr Robot, Chengdu, Sichuan, Peoples R China.^[Guo, J.] Univ South China, Sch Mech Engn, Hengyang 421000, Hunan, Peoples R China.
会议论文集名称：
Journal of Physics Conference Series
摘要：
Packaging process had been studied on capacitance accelerometer. The silicon-glass bonding process had been adopted on sensor chip and glass, and sensor chip and glass was adhered on ceramic substrate, the three-layer structure was curved due to the thermal mismatch, the slice error of glass lead to asymmetrical curve of sensor chip. Thus, the sensitive mass of accelerometer deviated along the sensitive direction, which was caused in zero offset drift. It was meaningful to confirm the influence of slice error of glass, the simulation results showed that the zero output drift was 12.3x10-3 m/s2 when the deviation was 40 mu m.
摘要：
The 3D micro/nano electroporation for transfection has become a powerful biological cell research technique with the development of micro-nano manufacturing technology. The micro channels connected the cells with transfection reagents on the chip were important to the transmemnbrane potentical, which directly influences the electroporation efficiency. In this study, a two-dimensional model for electroporation of cells was designed to address the effects of channels' sizes and number on transmembrane potential. The simulation results indicated that the transmembrane potential increased with increasing size of channels' entrances. Moreover, compared with single channel entrance, the transmembrane potential was higher when the cells located at multiple channels entrances. These results suggest that it IS required to develop higher micro manufacturing technology to create channels as we expected size.
作者机构：
[Shen, Jiang; Tang, Xiaohuan; Wang, Xiangjiang] Univ South China, Sch Mech Engn, Hengyang, Hunan, Peoples R China.
会议名称：
International Conference on Civil, Architecture and Environmental Engineering (ICCAE)
会议时间：
NOV 04-06, 2016
会议地点：
Taipei, TAIWAN
会议主办单位：
[Wang, Xiangjiang;Tang, Xiaohuan;Shen, Jiang] Univ South China, Sch Mech Engn, Hengyang, Hunan, Peoples R China.
会议论文集名称：
Proceedings of The 2016 International Conference on Civil, Architecture and Environmental Engineering（Vol.1）
摘要：
In order to solve the problem of the interval in the slider crank mechanism and improve its position accuracy, this article will establish a simplified model of the slider crank mechanism based on its simple mechanism, and make full use of the sensor to measure the movement parameters of each component of the slider crank mechanism. And then, in this article, the system parameter of the slider crank mechanism is identified via the parameter identification method, and finally the slider crank mechanism with interval will be set up and analyzed through the simulation experiment. The comparison results show that the model building via the parameter identification possesses high accuracy and a simple modelling process. Meanwhile, this kind of modelling method can afford a new thinking for the modelling of the complex and non-linear electromechanical system.
摘要：
In this paper, a new type of magnetic wheeled wall climbing robot is proposed in order to overcome the shortcomings of existing climbing robots. It takes advantage of SOLIDWORKS to establish a three-dimensional model. Also, the paper introduces the design idea of wall-climbing robot, uses MATLAB to do the numerical analysis and make magnetic simulation through ANSOFT MAXWELL.
会议名称：
International Conference on Fluid Mechanics and Industrial Applications (FMIA)
会议时间：
OCT 21-22, 2017
会议地点：
Taiyuan, PEOPLES R CHINA
会议主办单位：
[Deng, Jian;Lei, Zeyong;Zhong, Lin] Nan Hua Univ, Sch Mech Engn, Hengyang, Peoples R China.
会议论文集名称：
Journal of Physics Conference Series
摘要：
Uranium hydrometallurgy fixed bed is used to separate and extracting uranium compounds from the leaching of uranium ore. It is a very important equipment in the process of uranium purification. The distribution of the internal flow field of uranium hydrometallurgy fixed bed has great effect on the running efficiency of fixed bed. In this paper, on the basis of fluid mechanics, computational fluid dynamics software Fluent is used to numerical simulation for resin adsorption process in axial flow uranium hydrometallurgy, fixed bed that the diameter is 1600 mm and the height is 6800 mm and to research internal flow field distribution of the fixed bed. The results shows that the fluid distribution in the fixed bed is uneven in the process of adsorbent resin adsorption. The groove shunt filter plate at the exit is a powerful measure to realize the uniform distribution of fluid in the resin layer of fixed bed.
关键词：
3D Printers;FDM technology;Silk Material Replacement Device
摘要：
The overall design of the mechanical structure of the color 3D printer is put forward, and a new spliced print head structure is proposed. The utility model relates to a splicing type print head, which is composed of a print head which is loaded with different colors of silk material and a movable fixing device of a spray head. The print head spliced through a nozzle fixing device of an elastic spring mechanism locking positioning clamping space forming and the print head, the splicing type print head in the two part of the implementation of the print head movement path splicing preset, and then through the automatic replacement process of printing head fixing device and mobile splicing nozzle with different colors from to achieve different color silk. An automatic replacement device of the wire material is designed. By testing the automatic replacement device of the wire material, it is proved that the automatic replacement of silk material in line with color 3D printing in the automatic replacement of silk material requirements.
摘要：
Cavitation nozzle is the core component of cavitation generator. It promotes cavitation by its internal special structure, producing bubble and improving the impact force of jet. The structural characteristics directly affect the quality of the cavitation jet. Therefore, the study of internal structure of nozzle is helpful to improve the performance of nozzle. Based on CFD software, taking the Helmholtz nozzle as the object, the numerical simulations of internal flow field and external flow field in nozzle with different structure have been carried out. At the same time, the influence law of cavitation jet by various parameters and structural optimization of Helmholtz cavitation nozzle has been analyzed.
摘要：
A new type of crawler-type magnetic adsorption wall-climbing robot for derusting of ships was designed. The three-dimensional model of the robot, the adsorption device and the cleaning device, were established by SOLIDWORKS, and the static force model was established according to the actual working condition. Then, two kinds of common overturning risks of the wall-climbing robot were analyzed and the numerical simulation carried out by MATLAB software was used to obtain the minimum adsorption force. At last, the magnetic adsorption unit was simulated by ANSOFT MAXWELL, and the vector magnetic density is obtained, verifying the rationality of the design of the adsorption unit.
作者机构：
[Lv Xi Jian; Zhao Ruilan; Tang De Wen; Liu Jun] Univ South China, Sch Mech Engn, Hengyang 421001, Hunan, Peoples R China.
会议名称：
5th International Conference on Measurement, Instrumentation and Automation (ICMIA)
会议时间：
SEP 17-18, 2016
会议地点：
Shenzhen, PEOPLES R CHINA
会议主办单位：
[Tang De Wen;Zhao Ruilan;Lv Xi Jian;Liu Jun] Univ South China, Sch Mech Engn, Hengyang 421001, Hunan, Peoples R China.
会议论文集名称：
Advances in Intelligent Systems Research
关键词：
Milling force;milling temperature;finite element model
摘要：
Both milling force and temperature are the key influence factor of thin-wall part deformation. Therefore, to study the influence of milling parameters including milling speed, feed per tooth, radial depth of cutting and axial depth of cutting on milling force and temperature in the cutting process,the finite element model of high speed milling thin-wall SDK11 hardened steel part is developed by DEFORM-3D based on the modified J-C material model. The results indicate that milling force increases with an increase of milling speed until milling speed beyond 400m/min began to decline, and milling temperature increases with an increase of cutting speed. Milling force rises with fluctuations with an increase of milling speed, and milling temperature increases with an increase of milling feed, But it appears a decline trend from milling feed of 0.02mm/z to 0.025mm/z. Both milling force and temperature are increasing with the radial and axial depth of cut increasing. but milling force decline and milling temperature increase rapidly from axial depth of 0.7mm to 0.8mm.
作者机构：
[Lin, Guo-Xiang; Chen, Ai-Hua; Tang, Yong-Hui] Univ South China, Sch Mech Engn, Hengyang 421001, Hunan, Peoples R China.
会议名称：
International Conference on Design, Manufacturing and Mechatronics (ICDMM)
会议时间：
APR 17-18, 2015
会议地点：
Adv Sci Technol & Ind Res Ctr, Wuhan, PEOPLES R CHINA
会议主办单位：
Adv Sci Technol & Ind Res Ctr
关键词：
Evidence theory;ventilation equipment and facilities;reliability
摘要：
A new solution to the reliability evaluation of mine ventilation equipment and facility was proposed using the combined method of evidence theory and neutral network. The outputs of multiple BP neural networks were firstly used as the basic probability distribution function of evidence theory. Then data fusion was conducted and the security degree of ventilation system was obtained according to the rules of evidence combination. The example showed that the result of this method was reasonable, objective and also very effective to the reliability evaluation of mine ventilation equipment and facility. The output of single BP neutral network was unstable. Therefore, the effect of the number of BP network on the instability of network was also analyzed by comparing the uncertainty after data fusion in different number of selected BP networks.
摘要：
In order to deal with the large amount of transmission data of the collaborative feature modelling, a new feature-based descriptive semantic-collaborative modeling method was proposed in this paper. Firstly the semantic description of the features for a product model was analyzed. Then through extensive Markup Language (XML) to describe incremental feature and use it for data exchange. At last, features recognition mechanism was used to parse XML data information, separating modelling function from implementation method of the CAD system that participates in collaborative modelling. They can communicate with each other well and do not need form a one-to-one relationship in the process of collaborative modelling, so as to realize collaborative modelling.
摘要：
In this paper, we study the character of solute transport in in-situ leaching of uranium in some sandstone uranium deposit in Xinjiang and analyze the effect of convection, molecular diffusion, mechanical dispersion, adsorption, chemical reaction and radioactive decay on migration and distribution of solute in sandstone uranium deposit. The process of in-situ leaching of uranium in sandstone uranium deposit and shrinkage model of leaching core is divided into 3 interfaces, basic equation of solute transport of in-situ leaching of uranium in homogeneous isotropic sandstone uranium deposit is derived, based on law of mass conservation, the hydrodynamic dispersion coefficient and retardation coefficient of solute transport are determined by analysis-optimization method, the calculated values of solution concentration are consistent with the ones of fitting curve of experimental test values by analysis-optimization parameters and the efficiency of our mathematical model is verified through field test of in-situ leaching.
会议名称：
International Conference on Design, Manufacturing and Mechatronics (ICDMM)
会议时间：
APR 17-18, 2015
会议地点：
Adv Sci Technol & Ind Res Ctr, Wuhan, PEOPLES R CHINA
会议主办单位：
Adv Sci Technol & Ind Res Ctr
关键词：
Direct modeling;SpaceClaim;beam model;CAE pre-processing
摘要：
SpaceClaim is a direct three-dimensional solid modeling software, not only with other 3D software for data exchange, also has a highly intelligent model changes and cleaning functions, such as beam model can be extracted from the solid model inside. For this reason, SpaceClaim for CAE analysis, rapid prototyping and 3D printing provides the best pre-processing tools.
