摘要：
Aim To explore and explain the mechanisms that influence surface acting in nursing students with different characteristics.
To explore and explain the mechanisms that influence surface acting in nursing students with different characteristics.
Background Nurses are now expected to deliver patient-centered care which necessitates the emotional labor. Surface acting, a form of emotional labor, can lead to negative outcomes. Given that nursing students are the backbone of the future nursing profession, there is an urgent need to investigate their surface acting tendencies and identify potential factors for early intervention.
Nurses are now expected to deliver patient-centered care which necessitates the emotional labor. Surface acting, a form of emotional labor, can lead to negative outcomes. Given that nursing students are the backbone of the future nursing profession, there is an urgent need to investigate their surface acting tendencies and identify potential factors for early intervention.
Design A cross-sectional study.
A cross-sectional study.
Methods This study was surveyed in a vocational college in Gansu, China. Participants completed the general information questionnaire, Bem Sex Role Inventory, Professional Identity Questionnaire of Nursing Students and Surface Acting Scale. K-means cluster analysis was performed, followed by random forest algorithm and SHapley Additive exPlanations based on Python program.
This study was surveyed in a vocational college in Gansu, China. Participants completed the general information questionnaire, Bem Sex Role Inventory, Professional Identity Questionnaire of Nursing Students and Surface Acting Scale. K-means cluster analysis was performed, followed by random forest algorithm and SHapley Additive exPlanations based on Python program.
Results A total of 1241 nursing students from vocational college were investigated and were clustered into 4 groups. The five dimensions of professional identity had higher feature importance in all four groups, with professional self-image having the highest feature importance in Cluster 3. Professional self-image and understanding retention benefits and turnover risks were negative predictors of surface acting in all four groups. Social comparison and self-reflection, independence of career choice and social modeling regarding nursing profession were positively correlated with surface acting in specific groups. In Cluster 1, there exists a positive correlation between professional self-image and the constructs of social comparison and self-reflection; as well as a negative correlation between maternal education and understanding of retention benefits and turnover risks.
A total of 1241 nursing students from vocational college were investigated and were clustered into 4 groups. The five dimensions of professional identity had higher feature importance in all four groups, with professional self-image having the highest feature importance in Cluster 3. Professional self-image and understanding retention benefits and turnover risks were negative predictors of surface acting in all four groups. Social comparison and self-reflection, independence of career choice and social modeling regarding nursing profession were positively correlated with surface acting in specific groups. In Cluster 1, there exists a positive correlation between professional self-image and the constructs of social comparison and self-reflection; as well as a negative correlation between maternal education and understanding of retention benefits and turnover risks.
Conclusions Professional identity significantly influences surface acting behaviors among nursing students, with professional self-image serving as a key negative predictor. Positive family conditions, access to educational resources, parental literacy, masculine or feminine gender roles and first-year nursing students, these traits have implications when dimensions of professional identity are used to predict surface acting behaviors.
Professional identity significantly influences surface acting behaviors among nursing students, with professional self-image serving as a key negative predictor. Positive family conditions, access to educational resources, parental literacy, masculine or feminine gender roles and first-year nursing students, these traits have implications when dimensions of professional identity are used to predict surface acting behaviors.
期刊：
FRONTIERS IN ONCOLOGY,2025年15:1515502 ISSN：2234-943X
通讯作者：
Yan, YY
作者机构：
[Mo, Wenjuan; Li, Mengnan] Univ South China, Sch Nursing, Hengyang Med Sch, Hengyang, Hunan, Peoples R China.;[Yan, YY; Yan, Yuanyuan; Fu, Guang] Univ South China, Affiliated Hosp 1, Dept Gastrointestinal Surg, Hengyang, Peoples R China.
通讯机构：
[Yan, YY ] U;Univ South China, Affiliated Hosp 1, Dept Gastrointestinal Surg, Hengyang, Peoples R China.
关键词：
best evidence;gastric cancer;intervention strategies;prevention;pulmonary complications
摘要：
BACKGROUND: Postoperative pulmonary complications in gastric cancer surgery significantly impact patient recovery and prognosis. These complications, including infections, can increase hospital stays and costs, and even lead to death. Numerous risk factors are involved, such as age, smoking history, and lung function. Although preventive measures exist, a unified and effective strategy is lacking. Therefore, researching and implementing effective prevention measures is crucial for improving patients' postoperative quality of life and survival rates. AIM: To collate and summarize the best available evidence for the prevention of pulmonary complications in patients undergoing gastric cancer surgery, thereby providing a reference for the clinical development of relevant intervention strategies. METHODS: A literature search was conducted in databases including BMJ Best Practice, UpToDate, JBI, Cochrane Library, PubMed, Embase, the Ontario Nurses Registration Network, the U.S. National Clinical Practice Guidelines, and MedLine, for documents related to the prevention of pulmonary complications in gastric cancer surgery patients. The search period extended from the inception of these databases to July 25, 2024. The quality of the literature was evaluated according to the standards of the Joanna Briggs Institute (JBI) Evidence-Based Health Care Center, and evidence was extracted from the included documents. RESULTS: A total of 27 documents were ultimately included. The extracted content encompassed three areas: preoperative assessment, risk prevention and intervention measures, totaling 31 best evidences across five categories. The findings of our study underscore the significance of comprehensive preoperative assessments, such as the ARISCAT index for pulmonary risk evaluation, and stress the importance of preoperative interventions like inspiratory muscle training, smoking cessation, and oral care in mitigating postoperative pulmonary complications (PPCs) following gastric cancer surgery. We also advocate for the adoption of protective lung ventilation strategies during surgery and continuous pulse oximetry monitoring postoperatively, along with targeted treatments for specific complications. CONCLUSION: The best evidence extracted for the prevention of complications in gastric cancer surgery patients serves as a basis for evidence-based practice for the prevention of pulmonary complications in this patient group. Further research topics on pulmonary complications of gastric cancer, we recommend further optimization of preoperative assessment tools, investigation into the efficacy of smoking cessation programs, comparative studies on intraoperative ventilation strategies, development of postoperative rehabilitation programs, and research into culturally and resource-sensitive interventions to broaden the global applicability of these practices.
作者：
Liang, Cong;Huang, Xinlin;Pu, Yucui;Zhang, Pei;Wang, Rong
期刊：
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES,2025年34(1):108104 ISSN：1052-3057
通讯作者：
Rong Wang
作者机构：
[Zhang, Pei; Liang, Cong] School of Nursing, University of South China, Heng Yang, 421001, China;[Liang, Cong] Yellow River Centre Hospital of the Yellow River Conservancy Commission, Zheng Zhou, 450000, China. Electronic address: 983849974@qq.com;[Huang, Xinlin] The Hong Kong Polytechnic University, Hong Kong, China;[Pu, Yucui] Chongqing Preschool Education College, Chong Qing, China;[Wang, Rong] School of Nursing, University of South China, Heng Yang, 421001, China. Electronic address: wwrr77@163.com
通讯机构：
[Rong Wang] S;School of Nursing, University of South China, Heng Yang, 421001, China
关键词：
Genome-wide association study;Mendelian randomization;Stroke;Walking pace
摘要：
Background Walking pace (WP), a simple physiological indicator, has been found to be strongly associated with a variety of health outcomes in recent years. Among them, the relationship between walking pace and stroke is of particular interest. Given the high morbidity, disability and mortality associated with stroke, identifying modifiable indicators of health, such as walking pace, could help in stroke prevention strategies. However, the causal relationship between WP and stroke risk remains unclear. This study aims to determine the causal relationship between walking pace and risk of stroke using a two-sample Mendelian randomization approach in a European-ancestry population.
Walking pace (WP), a simple physiological indicator, has been found to be strongly associated with a variety of health outcomes in recent years. Among them, the relationship between walking pace and stroke is of particular interest. Given the high morbidity, disability and mortality associated with stroke, identifying modifiable indicators of health, such as walking pace, could help in stroke prevention strategies. However, the causal relationship between WP and stroke risk remains unclear. This study aims to determine the causal relationship between walking pace and risk of stroke using a two-sample Mendelian randomization approach in a European-ancestry population.
Methods In order to evaluate the potential for a causal relationship between WP and stroke in people of European heritage, a two-sample Mendelian randomization (MR) study was carried out. Statistics about the association of single nucleotide polymorphisms (SNPs) with stroke were taken from FinnGen (R8) (n = 284,040), while the UK Biobank genome-wide association studies (GWAS) provided the summary data on the association of SNPs with WP (n = 459,915). The inverse-variance weighted (IVW) method was utilised as the primary strategy to examine the causal connection between WP and stroke. Additionally, complementary analyses were conducted using the MR-Egger and weighted median. In order to identify the potential directional pleiotropy and heterogeneity, the MR-Egger intercept test, the MR-PRESSO test, and Cochran's Q statistic were all carried out. This connection was evaluated using OR with 95% confidence intervals (CIs).
In order to evaluate the potential for a causal relationship between WP and stroke in people of European heritage, a two-sample Mendelian randomization (MR) study was carried out. Statistics about the association of single nucleotide polymorphisms (SNPs) with stroke were taken from FinnGen (R8) (n = 284,040), while the UK Biobank genome-wide association studies (GWAS) provided the summary data on the association of SNPs with WP (n = 459,915). The inverse-variance weighted (IVW) method was utilised as the primary strategy to examine the causal connection between WP and stroke. Additionally, complementary analyses were conducted using the MR-Egger and weighted median. In order to identify the potential directional pleiotropy and heterogeneity, the MR-Egger intercept test, the MR-PRESSO test, and Cochran's Q statistic were all carried out. This connection was evaluated using OR with 95% confidence intervals (CIs).
Results A total of 48 SNPs were identified as valid instrumental variables in our two-sample MR analysis. The result showed that a slower walking pace is associated with a higher risk of stroke (OR = 0.573; 95% CI, 0.383-0.858, P = 0.007). The “leave-one-out” analysis demonstrated that the absence of a single SNP did not affect the robustness of our results. The MR-Egger intercept test indicated that genetic pleiotropy did not introduce bias into the results [intercept = −2.9E−03, SE = 0.008, P = 0.719] and Cochran's Q test revealed no heterogeneity. Therefore, the sensitivity analyses yielded comparable results. Consequently, the results of the sensitivity analyses were consistent.
A total of 48 SNPs were identified as valid instrumental variables in our two-sample MR analysis. The result showed that a slower walking pace is associated with a higher risk of stroke (OR = 0.573; 95% CI, 0.383-0.858, P = 0.007). The “leave-one-out” analysis demonstrated that the absence of a single SNP did not affect the robustness of our results. The MR-Egger intercept test indicated that genetic pleiotropy did not introduce bias into the results [intercept = −2.9E−03, SE = 0.008, P = 0.719] and Cochran's Q test revealed no heterogeneity. Therefore, the sensitivity analyses yielded comparable results. Consequently, the results of the sensitivity analyses were consistent.
Conclusion Our MR study revealed that WP is inversely associated with risk of stroke. These results provided evidence that slower WP causally increased the risk of stroke, recommending that patients with lower WP should have a prompt physical examination and targeted interventions to reduce their risk of stroke and enhance their quality of life.
Our MR study revealed that WP is inversely associated with risk of stroke. These results provided evidence that slower WP causally increased the risk of stroke, recommending that patients with lower WP should have a prompt physical examination and targeted interventions to reduce their risk of stroke and enhance their quality of life.
摘要：
China is experiencing an increasingly serious aging population. Cognitive function is an important factor and guarantee for the quality of life of older people. Therefore, to achieve healthy aging, this study aimed to examine the sequential multiple mediating effects of indoor ventilation frequency and cognitive function on anxiety and self-rated health in the Chinese older people population. Using the 2018 China Longitudinal Health and Longevity Survey (CLHLS) dataset, we finally selected 10,372 Chinese seniors over the age of 65. First, we describe the basic socio-demographic information of the sample population. Second, Spearman correlation analysis was used to determine whether there was a correlation between indoor ventilation frequency, anxiety, self-rated health, and cognitive function among Chinese older people. Finally, the SPSS macro process program was used to complete the sequence multiple mediation analysis. Indoor ventilation frequency, anxiety, self-rated health and cognitive function were significantly correlated (p < 0.01). Indoor ventilation frequency not only has a direct positive impact on the cognitive function of older people (effect = 0.1427; Standard error = 0.0201; 95%CI: LL = 0.1034, UL = 0.1821), but also indirectly affected cognitive function through three pathways: independent mediation of anxiety (effect = 0.0078; Standard error = 0.0021; 95%CI: LL = 0.0041, UL = 0.0121), independent mediating effect of self-rated health (effect = 0.0154; Standard error = 0.0030; 95%CI: LL = 0.0098, UL = 0.0215), and the chain mediating effect between anxiety and self-rated health (effect = 0.0046; Standard error = 0.0009; 95%CI: LL = 0.0029, UL = 0.0065). All projects are self-reported and some results may be biased. In the future, it may be more inspiring to explore more detailed and specific effects of indoor air quality on cognitive function in older people. Studies have shown that indoor ventilation frequency can improve cognitive function by reducing anxiety and improving self-rated health in older people Chinese. Encouraging older adults to increase the frequency of indoor ventilation will benefit their mental health and cognitive function. This study provides empirical evidence for the association between indoor ventilation frequency and cognitive function in older people Chinese adults. We used nationally representative data to investigate the relationship between indoor ventilation frequency and cognitive function and further explored the mediating role of anxiety and self-rated health in Chinese older adults. Indoor ventilation frequency can not only directly affect cognitive function in older people, but also indirectly affect cognitive function through anxiety and self-rated health. Anxiety and self-rated health have a series of mediating effects between indoor ventilation frequency and cognitive function.
期刊：
Microbes and Infection,2025年:105505 ISSN：1286-4579
通讯作者：
Li, Zhongyu
作者机构：
[Wang, Xinglv; Wu, Hongrong; Zhang, Jingrong; Chen, Lili; Tang, Chengyu] Institute of Pathogenic Biology, School of Nursing, Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China;[Li, Zhongyu] Institute of Pathogenic Biology, Medical College of Hengyang, University of South China, No. 28, Changsheng West Road, Hengyang, 421001, Hunan, China. Electronic address: lzhy1023@hotmail.com
通讯机构：
[Li, Zhongyu] I;Institute of Pathogenic Biology, Medical College of Hengyang, University of South China, No. 28, Changsheng West Road, Hengyang, 421001, Hunan, China. Electronic address:
摘要：
Genital tract Chlamydia trachomatis (Ct) infection is one of the most prevalent sexually transmitted infections (STIs) worldwide. However, its clinical progression is often insidious and prolonged. Understanding the mechanisms by which Ct influences cell death pathways is crucial for elucidating the pathogenic processes of this intracellular bacterium. Ferroptosis, a newly identified form of programmed cell death, is characterized by the iron-dependent accumulation of lipid peroxides. Despite its relevance, the interaction between Ct and ferroptosis remains poorly studied. In the present study, we first performed bioinformatics analysis based on RNA sequencing data under an in vitro model of Ct acute infection. Bioinformatics analysis revealed significant enrichment of differentially expressed genes in ferroptosis and p53 signaling pathways. Subsequently, we validated the hypothesis that Ct inhibits host ferroptosis by expression assays of ferroptosis-related proteins. Further cell proliferation, intracellular ferrous iron fluorescence, and lipid peroxidation assays multifaceted observations of the phenotype. Mechanistically, we found that Ct inhibition of ferroptosis acts by regulating the host p53/SLC7A11 pathway. Finally, indirect immunofluorescence assays demonstrated that ferroptosis decreases inclusion forming units (IFUs) of Ct progeny and thus affects its reproduction, which partly explains Ct 's survival strategy of resisting host ferroptosis.
Genital tract Chlamydia trachomatis (Ct) infection is one of the most prevalent sexually transmitted infections (STIs) worldwide. However, its clinical progression is often insidious and prolonged. Understanding the mechanisms by which Ct influences cell death pathways is crucial for elucidating the pathogenic processes of this intracellular bacterium. Ferroptosis, a newly identified form of programmed cell death, is characterized by the iron-dependent accumulation of lipid peroxides. Despite its relevance, the interaction between Ct and ferroptosis remains poorly studied. In the present study, we first performed bioinformatics analysis based on RNA sequencing data under an in vitro model of Ct acute infection. Bioinformatics analysis revealed significant enrichment of differentially expressed genes in ferroptosis and p53 signaling pathways. Subsequently, we validated the hypothesis that Ct inhibits host ferroptosis by expression assays of ferroptosis-related proteins. Further cell proliferation, intracellular ferrous iron fluorescence, and lipid peroxidation assays multifaceted observations of the phenotype. Mechanistically, we found that Ct inhibition of ferroptosis acts by regulating the host p53/SLC7A11 pathway. Finally, indirect immunofluorescence assays demonstrated that ferroptosis decreases inclusion forming units (IFUs) of Ct progeny and thus affects its reproduction, which partly explains Ct 's survival strategy of resisting host ferroptosis.
摘要：
AIMS: Although anxiety and depression are frequently linked to coronary heart disease, a network analysis of comorbid anxiety and depression and their association with quality of life in patients undergoing percutaneous coronary intervention (PCI) remains unclear from the perspective of symptom interactions. We aimed to investigate the network structure and symptom patterns of anxiety and depression, and their relationship with quality of life in patients undergoing PCI. METHODS AND RESULTS: This study included 528 patients undergoing PCI. The seven-item Generalized Anxiety Disorder Scale, nine-item Patient Health Questionnaire, and World Health Organization Quality of Life Questionnaire-Brief Version were used as measurement tools. The R software was used to construct and interpret the network structure. The symptoms "sleep disturbance," "irritability," and "uncontrollable worry" showed the highest expected influence centrality. Three bridge symptoms were identified: "sleep disturbance," "excessive worry," and "trouble relaxing." Among the three strongest edges, two were associated with anxiety and depressive symptoms. Ten symptoms were directly associated with quality of life, with "fatigue" showing the strongest relationship. In the network comparison test, significant differences in global strength were observed between the male and female groups. CONCLUSION: "Sleep disturbance," plays a critical role in the current network, while "excessive worry," "trouble relaxing," and "fatigue" were identified as key priorities owing to their high correlation with "sleep disturbance" and quality of life. Focusing on these symptoms may help mitigate the risk of multiple-symptom interactions and provide tailored intervention measures for patients undergoing PCI. REGISTRATION: Chinese Clinical Trial Registry ChiCTR230007581.
期刊：
Asia-Pacific Journal of Oncology Nursing,2025年12:100702 ISSN：2347-5625
通讯作者：
Chen, YY
作者机构：
[Guo, Junchen; Xu, Xianghua; Chen, Yongyi; Hu, Yonghong] Hunan Canc Hosp, Dept Palliat Care, Changsha, Peoples R China.;[Guo, Junchen] Univ Wollongong, Sch Nursing, Wollongong, NSW, Australia.;[Zeng, Linghao] Univ South China, Sch Nursing, Hengyang, Peoples R China.;[Dai, Yunyun] Univ Wollongong, Hlth Serv Res Inst, Wollongong, NSW, Australia.
通讯机构：
[Chen, YY ] H;Hunan Canc Hosp, Dept Palliat Care, Changsha, Peoples R China.
关键词：
Palliative care;Shared-care management;Delphi technique;End of life care
摘要：
Objective Shared-care management (SCM) in palliative care is a collaborative model where shared care teams work in partnership with patients' original healthcare providers, employing multimodal strategies including consultations and coordinated referrals to enhance quality of care for patients. The evidence regarding its implementation remains fragmented and lacks detailed explanations, which impedes its application in clinical practice. This study aimed to develop a SCM standard of palliative care in adults in mainland regions of China.
Shared-care management (SCM) in palliative care is a collaborative model where shared care teams work in partnership with patients' original healthcare providers, employing multimodal strategies including consultations and coordinated referrals to enhance quality of care for patients. The evidence regarding its implementation remains fragmented and lacks detailed explanations, which impedes its application in clinical practice. This study aimed to develop a SCM standard of palliative care in adults in mainland regions of China.
Methods Initial standard framework identification was achieved via literature evidence summary. From April to August 2024, two rounds of Delphi method was conducted with the purposes of modifying the standard. To establish consensus, items with a mean importance score > 3.50 and the coefficient of variation of item scores < 0.25 were retained.
Initial standard framework identification was achieved via literature evidence summary. From April to August 2024, two rounds of Delphi method was conducted with the purposes of modifying the standard. To establish consensus, items with a mean importance score > 3.50 and the coefficient of variation of item scores < 0.25 were retained.
Results The first round involved 35 experts, with a follow-up participation of 33 in the second round. The Kendall concordance coefficients of the two rounds of experts consultation were 0.128 and 0.134, respectively (all P < 0.001), indicating consensus among the experts. At the end of the second round, the average importance score of each item was 4.73-5.00. A total of 8 modules including SCM team, applicable population, process of SCM, contents of SCM, start time, precautions, effectiveness evaluation and quality control, and the corresponding 22 items were finally identified in this standard.
The first round involved 35 experts, with a follow-up participation of 33 in the second round. The Kendall concordance coefficients of the two rounds of experts consultation were 0.128 and 0.134, respectively (all P < 0.001), indicating consensus among the experts. At the end of the second round, the average importance score of each item was 4.73-5.00. A total of 8 modules including SCM team, applicable population, process of SCM, contents of SCM, start time, precautions, effectiveness evaluation and quality control, and the corresponding 22 items were finally identified in this standard.
Conclusions The establishment of the standard in this study provides a critical framework that can be adopted by healthcare institutions to ensure that SCM services are delivered uniformly and effectively in mainland regions of China.
The establishment of the standard in this study provides a critical framework that can be adopted by healthcare institutions to ensure that SCM services are delivered uniformly and effectively in mainland regions of China.
摘要：
BACKGROUND: To investigate the association between indoor ventilation frequency and symptoms of depression and anxiety in older persons. METHODS: A binary logistic regression model was used to analyze the effects of indoor ventilation frequency on depression and anxiety by using data from the 2018 Chinese longitudinal healthy longevity survey (CLHLS). RESULTS: A total of 9,690 older persons with an average age of (83.20 ± 11.27) years were included, including 4,458 males (46.0%) and 5,232 females (54.0%). The average score of indoor ventilation frequency was (6.06 ± 1.98) points, including 770 people (7.9%) with low frequency, 3,066 people (31.6%) with medium frequency, and 5,854 people (60.4%) with high frequency. 842 (8.7%) had symptoms of depression and 204 (2.1%) had symptoms of anxiety. Compared with the older persons with low indoor ventilation frequency, the older persons with higher ventilation frequency had a lower incidence of depression (OR(95%CI) = 1.92 (1.50 ∼ 2.46), 1.51 (1.27 ∼ 1.79); P < 0.001). However indoor ventilation frequency was not associated with anxiety symptoms. CONCLUSION: Indoor ventilation frequency is related to depressive symptoms in older persons. Communities and families should pay more attention to indoor ventilation and intervene in time to promote and improve the mental health of older persons.
期刊：
Journal of Orthopaedic Surgery and Research,2025年20(1):1-8 ISSN：1749-799X
通讯作者：
Zhou, YH;Huang, HY
作者机构：
[He, Yulian; Liu, Bo; Tang, Wen; Yuan, Runzhi] Univ South China, Affiliated Hosp 1, Dept Orthoped Ctr, Hengyang Med Sch, Hengyang City 421001, Hunan Prov, Peoples R China.;[Wang, Yiqi] Univ South China, Sch Nursing, Hengyang City 421001, Hunan Prov, Peoples R China.;[Zhou, Yanhui] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Nursing Dept, 69 Chuanshan Rd, Hengyang City 421001, Hunan Prov, Peoples R China.;[Huang, Huayong; Huang, HY] Univ South China, Affiliated Hosp 1, Dept Emergency Med Ctr, Hengyang Med Sch, 69 Chuanshan Rd, Hengyang City 421001, Hunan Prov, Peoples R China.
通讯机构：
[Huang, HY ; Zhou, YH ] U;Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Nursing Dept, 69 Chuanshan Rd, Hengyang City 421001, Hunan Prov, Peoples R China.;Univ South China, Affiliated Hosp 1, Dept Emergency Med Ctr, Hengyang Med Sch, 69 Chuanshan Rd, Hengyang City 421001, Hunan Prov, Peoples R China.
关键词：
Early rehabilitation;Hospital stay;Postoperative complications;Elderly patients;Hip fracture;A prospective cohort study
摘要：
Hip fractures in the elderly are a major global public health concern, with incidence projected to rise as populations age. Rehabilitation is critical to recovery after hip fracture surgery, but the ideal timing for initiation remains uncertain. While early rehabilitation, within 48 h post-surgery, is associated with better outcomes, its specific impact on hospital stay duration and postoperative complications is not yet conclusively established. This study aims to evaluate the effects of initiating rehabilitation within 48 h after hip fracture surgery on hospital length of stay and postoperative complications, compared to rehabilitation started one-week post-surgery in elderly patients. It is hypothesized that early rehabilitation will significantly reduce hospital stays and decrease the rate of postoperative complications. In this prospective cohort study, patients aged 65 and older are divided into early rehabilitation (within 48 h) and delayed rehabilitation (after one week) groups. Data will be collected using electronic medical records (EMR), standardized clinical tools (Barthel Index, Timed Up and Go), and patient-reported outcome measures (SF-36, EQ-5D). Statistical analyses will include t-tests and chi-square tests for outcome comparison, with multiple regression adjusting for potential confounders such as age, gender, and comorbidities. This study addresses a gap in current research by comparing early versus delayed rehabilitation for elderly hip fracture patients. The findings will contribute to the development of evidence-based rehabilitation protocols aimed at optimizing recovery, reducing complications, and improving the efficient use of medical resources.
摘要：
Background Anxiety is a common and significant problem in patients who need to undergo colonoscopy. However, the question of which non-pharmacological intervention is the best strategy to reduce anxiety in patients undergoing colonoscopy remains unanswered.
Anxiety is a common and significant problem in patients who need to undergo colonoscopy. However, the question of which non-pharmacological intervention is the best strategy to reduce anxiety in patients undergoing colonoscopy remains unanswered.
Objectives To evaluate and rank the effectiveness of various non-pharmacological interventions for reducing anxiety in patients undergoing colonoscopy in order to identify the most effective strategies.
To evaluate and rank the effectiveness of various non-pharmacological interventions for reducing anxiety in patients undergoing colonoscopy in order to identify the most effective strategies.
Methods We searched PubMed, Cochrane Library, Embase, Web of Science, and Medline for randomized controlled trials published from the database construction to March 2024. The primary outcome was the difference between pre- and post-intervention anxiety means. A network meta-analysis was conducted utilizing the “gemtc” package based on R4.3.0.
We searched PubMed, Cochrane Library, Embase, Web of Science, and Medline for randomized controlled trials published from the database construction to March 2024. The primary outcome was the difference between pre- and post-intervention anxiety means. A network meta-analysis was conducted utilizing the “gemtc” package based on R4.3.0.
Results The analysis encompassed 24 randomized controlled trials, incorporating 2525 participants and evaluating 9 non-pharmacological interventions. All non-pharmacological interventions reduced anxiety in patients undergoing colonoscopy compared to standard care, with music intervention (SMD = -0.52, 95 %CI (−0.84,-0.20)), audiovisual distraction (SMD = -0.54, 95 %CI(−0.96,-0.12)), video information (SMD = -1.47, 95 %CI(−2.03,-0.90)), individual education (SMD = -1.72, 95 %CI(−2.76,-0.70)), and electroacupuncture (SMD = -1.12, 95 %CI(−2.10,-0.13)) having statistically significant effects. SUCRA ranking identified the priority of individual education (SUCRA: 92.5 %) and video information (SUCRA: 87.7 %). Meta-regression and sensitivity analysis further demonstrated the stability of the evidence. The certainty of the evidence was mostly rated as medium to low.
The analysis encompassed 24 randomized controlled trials, incorporating 2525 participants and evaluating 9 non-pharmacological interventions. All non-pharmacological interventions reduced anxiety in patients undergoing colonoscopy compared to standard care, with music intervention (SMD = -0.52, 95 %CI (−0.84,-0.20)), audiovisual distraction (SMD = -0.54, 95 %CI(−0.96,-0.12)), video information (SMD = -1.47, 95 %CI(−2.03,-0.90)), individual education (SMD = -1.72, 95 %CI(−2.76,-0.70)), and electroacupuncture (SMD = -1.12, 95 %CI(−2.10,-0.13)) having statistically significant effects. SUCRA ranking identified the priority of individual education (SUCRA: 92.5 %) and video information (SUCRA: 87.7 %). Meta-regression and sensitivity analysis further demonstrated the stability of the evidence. The certainty of the evidence was mostly rated as medium to low.
Conclusion This review highlights the superior effects of individual education and video information in reducing anxiety in patients undergoing colonoscopy. The findings of our review could provide clinical decision-makers and healthcare practitioners, such as doctors and nurses, with evidence-based practices for selecting interventions to reduce anxiety in patients undergoing colonoscopy.
This review highlights the superior effects of individual education and video information in reducing anxiety in patients undergoing colonoscopy. The findings of our review could provide clinical decision-makers and healthcare practitioners, such as doctors and nurses, with evidence-based practices for selecting interventions to reduce anxiety in patients undergoing colonoscopy.
摘要：
Hypertrophic scarring (HS) is a fibrotic skin disorder characterized by excessive deposition of extracellular matrix (ECM), leading to symptoms such as pain, itching, and skin contraction. HS can also result in restricted joint mobility and cosmetic deformities, imposing psychological and economic burdens on patients. Additionally, it increases wound care costs, and currently, no ideal treatment options exist. Therefore, HS is not only a clinical care issue but also a societal problem, with significant challenges related to its management and prevention. In this study, a custom-made cepharanthine ointment was applied to a rabbit ear scar model to investigate its effects on morphology, histology, and protein expression in HS. Additionally, the mechanism underlying the effect of cepharanthine on affected fibroblasts and the expression of ECM proteins was explored in vitro models of fibrosis. Animal experiments demonstrated that cepharanthine significantly reduced the tissue scar hypertrophy index and collagen content, improved the arrangement of fibroblasts, and inhibited ECM production. Cellular experiments indicated that cepharanthine effectively downregulated key proteins in the TGF-β/SMAD pathway, decreased ECM protein expression, and suppressed fibroblast proliferation and migration. Cepharanthine can prevent HS by reducing ECM deposition through the TGF-β/SMAD signalling pathway.
作者机构：
[Rong-Jia Pan; Min Gui; Man-Yi Wang; Xiao-Shan Li] The First Affiliated Hospital, School of Nursing, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China;[Xiao-Yan Ni; Si-Jie Gui] The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China;[Xiu-Hong Lei] The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China;Joint Training Base for Nursing Postgraduates By University of South China and TD Care, Intelligent Nursing Research Center of Hunan Province, Hengyang, Hunan, 421001, China;[Cai-Xia Sun; Fei Wu; Gu-Qing Zeng] The First Affiliated Hospital, School of Nursing, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China<&wdkj&>Joint Training Base for Nursing Postgraduates By University of South China and TD Care, Intelligent Nursing Research Center of Hunan Province, Hengyang, Hunan, 421001, China
通讯机构：
[Gu-Qing Zeng] T;The First Affiliated Hospital, School of Nursing, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China<&wdkj&>Joint Training Base for Nursing Postgraduates By University of South China and TD Care, Intelligent Nursing Research Center of Hunan Province, Hengyang, Hunan, 421001, China
摘要：
Background and objectives To reach the goal of a 95 % reduction in Tuberculosis (TB) mortality by 2035 compared to 2015, it may be necessary for different regions to create specific intervention strategies tailored to their respective TB mortality components. This study aimed to investigate the causes of death among TB patients in China's developed cities.
To reach the goal of a 95 % reduction in Tuberculosis (TB) mortality by 2035 compared to 2015, it may be necessary for different regions to create specific intervention strategies tailored to their respective TB mortality components. This study aimed to investigate the causes of death among TB patients in China's developed cities.
Methods This retrospective cohort study included 8851TB patients registered at Shenzhen's largest TB-designated hospital between 2017 and 2022. The primary causes of death were categorized, and multivariable logistic regression was used to identify independent risk factors for TB mortality.
This retrospective cohort study included 8851TB patients registered at Shenzhen's largest TB-designated hospital between 2017 and 2022. The primary causes of death were categorized, and multivariable logistic regression was used to identify independent risk factors for TB mortality.
Results The study revealed a TB mortality rate of 1.6 % during the treatment period. Independent risk factors for TB mortality included male gender, older age, lower body mass index (BMI), anemia, and the presence of tumors. Notably, poor treatment adherence was significant contributors to mortality, even in this well-resourced urban environment. Additionally, the progression of the chronic disease emerged as a critical factor in TB-related deaths, particularly among patients with severe underlying conditions.
The study revealed a TB mortality rate of 1.6 % during the treatment period. Independent risk factors for TB mortality included male gender, older age, lower body mass index (BMI), anemia, and the presence of tumors. Notably, poor treatment adherence was significant contributors to mortality, even in this well-resourced urban environment. Additionally, the progression of the chronic disease emerged as a critical factor in TB-related deaths, particularly among patients with severe underlying conditions.
Conclusion This study underscores the importance of addressing treatment adherence and healthcare accessibility to reduce TB mortality, even in urban settings with robust healthcare infrastructure. The findings also highlight the need for integrated management of TB and chronic diseases, as well as early identification and management of underlying disease to improve patient outcomes. These insights are crucial for developing targeted interventions that can enhance TB care and reduce mortality in similar urban populations.
This study underscores the importance of addressing treatment adherence and healthcare accessibility to reduce TB mortality, even in urban settings with robust healthcare infrastructure. The findings also highlight the need for integrated management of TB and chronic diseases, as well as early identification and management of underlying disease to improve patient outcomes. These insights are crucial for developing targeted interventions that can enhance TB care and reduce mortality in similar urban populations.
作者机构：
[Li, C.; Hu, A.; You, Z.] Jinhua Univ Vocat Technol, Sch Med, Jinhua 321000, Zhejiang, Peoples R China.;[Liu, X.; Liu, Y.; Liu, F.; Liao, L.] Univ South China, Sch Nursing, Hengyang 421001, Hunan, Peoples R China.;[Li, W.; Liu, F.] Univ South China, Affiliated Hosp 1, Cardiac Intervent Imaging Ctr, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.;[Liu, F.] Chiang Mai Univ, Fac Nursing, PhD Degree Program, Chiang Mai 50000, Thailand.
通讯机构：
[Liu, F ] U;Univ South China, Sch Nursing, Hengyang 421001, Hunan, Peoples R China.;Univ South China, Affiliated Hosp 1, Cardiac Intervent Imaging Ctr, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.;Chiang Mai Univ, Fac Nursing, PhD Degree Program, Chiang Mai 50000, Thailand.
摘要：
objective: To assess the variations in radiation dose at different areas in the cardiac catheterization room during cardiac catheterization interventions. methods:To simulate the conventional operation in cardiac catheterization interventions, perform angiography on standard manikins ,the radiation dose was collected from 22 areas in the cardiac catheterization room under 8 projection angles, and each area was repeated 5 times, and the collected data was analyzed using one-way ANOVA and independent sample t-test. results:Analysis of the radiation dose in 22 areas under 8 projection angles revealed that the lowest radiation dose was found in the area at the end of the operating table in the cardiac catheterization room (p < 0.05), and the highest radiation dose was found in the area on the left and right sides of the X-ray tube (p < 0.05); the radiation dose in the area on the right side of the X-ray tube of the DSA machine was greater than that in the conventional standing area of the first operator (p < 0.05)，and the radiation dose in the conventional standing area of the second operator was greater than that in the conventional standing area of the first operator (p < 0.05); the radiation dose in the standing area of the first operator was highest in the cephalic position (CRA 30°) (p < 0.05), and the radiation dose in the standing area of the second operator was highest in the left anterior oblique position (LAO 45°) (p < 0.05); in the angle of RAO projection, the radiation dose in the right area of the X-ray tube was greater than that in the left area of the X-ray tube (p < 0.05). Under the RAO projection angle, the radiation dose from the right side of the X-ray tube of the DSA machine was greater than that from the left side (p<0.05), and the result was reversed at the projection angle of the LAO. conclusion:The radiation dose during cardiac catheterization interventions is lowest in the area at the end of the operating table, which can be used as a standing area for nurses and as an area for the placement of surgical equipment and supplies. At the same time, it is necessary to pay attention to the radiation dose to the second operator and to further improve the radiation protection measures for the second operator, and additional measures are needed to minimize the radiation dose to the operators in the cephalic position (CRA 30°) and in the left anterior oblique position (LAO 45°).
作者机构：
[You, Jia-Chun; Xu, Chao-Yue; Li, Shu-Lin; Huang, YJ; Huang, Yan-Jin; He, Zhi-Qing] Univ South China, Sch Nursing, Hengyang Med Sch, Hengyang, Hunan, Peoples R China.;[Zou, Ping] Nipissing Univ, Sch Nursing, North Bay, ON, Canada.;[Chen, Xi] Hong Kong Polytech Univ, Sch Nursing, Hong Kong, Peoples R China.
通讯机构：
[Huang, YJ ] U;Univ South China, Sch Nursing, Hengyang Med Sch, Hengyang, Hunan, Peoples R China.
摘要：
INTRODUCTION: Stroke presents a considerable burden not only to patients but also to their families and society at large. In many instances, stroke patients opt for home rehabilitation, relying on family caregivers for daily assistance. This dynamic significantly influences the physiological, psychological and social well-being of these caregivers. Despite its importance, the phenomenon of self-regulatory fatigue (SRF) among family caregivers has received insufficient attention in the literature. Therefore, the objective of this study is to investigate the levels of SRF, the characteristics of associated symptoms and the trajectories of symptom change experienced by family caregivers of stroke patients. METHODS AND ANALYSIS: This research employs a mixed-methods approach, combining a cross-sectional study with a prospective longitudinal quantitative and qualitative design. The Chinese version of the SRF Scale and the Chinese version of Patient-Reported Outcomes Measurement Information System profile-29 are used to assess SRF, psychological and physiological symptoms, and related functional outcomes among family caregivers of stroke patients. Latent class growth analysis will be employed to model the heterogeneous developmental trajectories of SRF-related symptoms among family caregivers of stroke patients. Reflexive thematic analysis will be employed to analyse, organise and summarise qualitative data, to identify the experiences and management needs related to SRF among family caregivers during home care. Through this comprehensive mixed-methods approach, the study aims to: investigate the levels of SRF experienced by family caregivers of stroke patients, identify patterns and trajectories of related symptoms. The integration of cross-sectional and longitudinal data allows for a thorough examination of both immediate and long-term aspects of caregiver experiences, providing valuable insights into the complex dynamics of SRF in this population. ETHICS AND DISSEMINATION: The study protocol was approved by the Medical Ethics Committee of the University of South China (approval number 2023-NHHL-051). Data collection was authorised by the ethics committees of the First Affiliated Hospital, Second Affiliated Hospital and Nanhua Affiliated Hospital of the University of South China. The results of this study will be disseminated through publication in pertinent peer-reviewed journals, presentation at local and international conferences, and communication with all relevant stakeholders. TRIAL REGISTRATION NUMBER: ChiCTR2400082717.
摘要：
Chlamydia trachomatis Pgp3 protein-induced immunoprotection is effective but incomplete, which requires the suitable adjuvants to enhance its immune response. Within this context, Hepatitis B core virus-like particles (HBc-VLP) emerge as nanoscale protein particles capable of incorporating either endogenous or exogenous antigens or epitopes. In this study, HBc-Pgp3 chimeric protein was accomplished by integrating the identified dominant epitope of the Pgp3 protein into the major immunodominant region of a truncated HBc-VLP, which was realized in the pET28a (+) vector and expressed via the E. coli BL21 expression system. The efficacious expression and purification of the recombinant HBc-Pgp3 facilitated a tripartite immunization regimen in mice. The immunological assessment encompassed the measurement of IgG antibody and cytokine levels through ELISA, alongside flow cytometric analysis of the CD4+ Th1 cell-mediated immune responses within the murine spleen. Comparative analysis revealed that the HBc-Pgp3-vaccinated mice demonstrated superior IgG antibody titers and subtypes relative to the controls. Moreover, the HBc-Pgp3 formulation was instrumental in augmenting IFN-γ production, enhancing the efficiency of Chlamydia muridarum clearance post-challenge, and severity of hydrosalpinx within the lower genital tract. Collectively, these findings illuminate the potential of the novel HBc-Pgp3 chimeric construct as an innovative vaccine candidate, offering augmented immunoprotection against chlamydial infection.
Chlamydia trachomatis Pgp3 protein-induced immunoprotection is effective but incomplete, which requires the suitable adjuvants to enhance its immune response. Within this context, Hepatitis B core virus-like particles (HBc-VLP) emerge as nanoscale protein particles capable of incorporating either endogenous or exogenous antigens or epitopes. In this study, HBc-Pgp3 chimeric protein was accomplished by integrating the identified dominant epitope of the Pgp3 protein into the major immunodominant region of a truncated HBc-VLP, which was realized in the pET28a (+) vector and expressed via the E. coli BL21 expression system. The efficacious expression and purification of the recombinant HBc-Pgp3 facilitated a tripartite immunization regimen in mice. The immunological assessment encompassed the measurement of IgG antibody and cytokine levels through ELISA, alongside flow cytometric analysis of the CD4+ Th1 cell-mediated immune responses within the murine spleen. Comparative analysis revealed that the HBc-Pgp3-vaccinated mice demonstrated superior IgG antibody titers and subtypes relative to the controls. Moreover, the HBc-Pgp3 formulation was instrumental in augmenting IFN-γ production, enhancing the efficiency of Chlamydia muridarum clearance post-challenge, and severity of hydrosalpinx within the lower genital tract. Collectively, these findings illuminate the potential of the novel HBc-Pgp3 chimeric construct as an innovative vaccine candidate, offering augmented immunoprotection against chlamydial infection.
摘要：
Objective This study examined the heterogeneity of illness perceptions in patients with lung cancer and evaluated the mediating role of self-transcendence in the relation between illness perception and demoralization.
This study examined the heterogeneity of illness perceptions in patients with lung cancer and evaluated the mediating role of self-transcendence in the relation between illness perception and demoralization.
Methods A convenience sample of 477 patients with lung cancer was selected from three tertiary hospitals in Wuhan, China, between January and June 2024. Participants completed the Brief Illness Perception Questionnaire, Self-Transcendence Scale, and Demoralization Scale. Data were analyzed using Mplus 8.3 and SPSS 25.0.
A convenience sample of 477 patients with lung cancer was selected from three tertiary hospitals in Wuhan, China, between January and June 2024. Participants completed the Brief Illness Perception Questionnaire, Self-Transcendence Scale, and Demoralization Scale. Data were analyzed using Mplus 8.3 and SPSS 25.0.
Results Three latent illness perception profiles were identified among patients with lung cancer: low (27.25%), moderate (40.04%), and high (32.71%). Mediation analyses revealed a partial mediation effect in the relation between illness perception and demoralization in the low versus moderate (SE = 1.56, 95% CI = 14.71, 20.86) and high versus low illness perception groups (SE = 1.71, 95% CI = 35.44, 42.71).
Three latent illness perception profiles were identified among patients with lung cancer: low (27.25%), moderate (40.04%), and high (32.71%). Mediation analyses revealed a partial mediation effect in the relation between illness perception and demoralization in the low versus moderate (SE = 1.56, 95% CI = 14.71, 20.86) and high versus low illness perception groups (SE = 1.71, 95% CI = 35.44, 42.71).
Conclusions Patients with lung cancer exhibited heterogeneous illness perceptions, and self-transcendence partially mediated the relation between illness perception and demoralization. Promoting self-transcendence may help mitigate the negative impact of illness perceptions on demoralization. Clinical interventions aimed at reducing negative illness perceptions and enhancing self-transcendence should be prioritized in the care of patients with lung cancer.
Patients with lung cancer exhibited heterogeneous illness perceptions, and self-transcendence partially mediated the relation between illness perception and demoralization. Promoting self-transcendence may help mitigate the negative impact of illness perceptions on demoralization. Clinical interventions aimed at reducing negative illness perceptions and enhancing self-transcendence should be prioritized in the care of patients with lung cancer.
作者机构：
[Shan Wu] School of Nursing, University of South China, Hengyang, China;[Fan Dai] Ji’an Vocational and Technical College, Ji’an, China;[Yanhong Wen; Chang Luo] Neurology Intensive Care Unit, Changsha Central Hospital Affiliated to University of South China, Changsha, China;[Chuanfang Wu] Department of Nursing, Changsha Central Hospital Affiliated to University of South China, Changsha, China
通讯机构：
[Chuanfang Wu] D;Department of Nursing, Changsha Central Hospital Affiliated to University of South China, Changsha, China
关键词：
Renal failure;Maintenance hemodialysis;Catheter related bloodstream infection;Nomogram;Prediction model
摘要：
To develop and validate of a nomogram for predicting Catheter related bloodstream infection(CRBSI) in patients with maintenance hemodialysis. This was a retrospective cohort study.A total of 756 patients underwent hemodialysis between January 2017 to December 2021 in purification center of the Affiliated Hospital of Changsha Central Hospital, University of South China were enrolled in this research.The demographic data, hemodialysis data, laboratory indexes of the patients were analyzed. Univariate analysis and multivariate Logistic regression were used to analyze the influencing factors of CRBSI in hemodialysis patients and a nomogram model was established.Area under the receiver operating characteristic curve(AUC) and Hosmer-Lemeshow(H-L)test were used to verify the discrimination and calibration of the model. Among the 756 hemodialysis patients,64 patients developed CRBSI, with an incidence rate of 8.5%(64/756).The results of multivariate analysis showed that combined with diabetes mellitus、dialysis age、catheter retention time、C-reactive protein and procalcitonin were independent risk factors for CRBSI in hemodialysis patients( P < 0.05).The receiver operating characteristic curve analysis showed that the AUC of the model was 0.88 and the H-L test results showed that the model had good goodness of fit(χ 2 = 5, P = 0.7).The internal validation of the prediction model showed an AUC of 0.82, and the H-L results showed (χ 2 = 11, P = 0.2), indicating that the model has a good prediction performance and high accuracy. An easy-to-use nomogram for prediction of CRBSI in hemodialysis patients is well developed.This risk assessment tool can effectively identify patients at high risk of CRBSI and may be useful for optimizing catheter management.
通讯机构：
[Liao, L ] U;Univ South China, Sch Nursing, Hengyang 421001, Hunan, Peoples R China.
关键词：
lymphedema;breast cancer survivors;social relationships;meta-aggregation
摘要：
Background: Breast Cancer-Related Lymphedema (BCRL) is a chronic condition requiring lifelong care, impacting survivors' quality of life. Social relationships play a crucial role in survivorship, yet research on their broader impact remains limited. Many Breast Cancer Survivors with Lymphedema (BCSWL) struggle with work, relationships, and self-esteem. This review explores their social experiences to inform healthcare strategies and improve self-management. Method: Based on the Joanna Briggs Institute meta-aggregation approach, article screening and data analysis were conducted following the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. The quality of the screened articles was evaluated using the Joanna Briggs Institute Critical Appraisal Checklist for Qualitative Research (JBI-QARI), and the Confidence in the Qualitative Synthesis of Findings (ConQual) approach was conducted to grade aggregated findings. Results: This review included 14 studies and focused primarily on 4 types of relationships: family, work colleagues, romantic relationships, and all relational partners (with some papers discussing overlapping relationship themes). We identified 4 synthesized findings that explore the experiences of BCSWL under different social relationships: (a) negotiating health and role expectations, (b) experiencing psychosocial pressure and stigmatization, (c) experiencing support from social networks, and (d) developing adaptive resilience and identity reconstruction. Conclusions: BCSWL experience complex and multifaceted outcomes within various social relationships, with both positive and negative experiences shaping their health and well-being. Findings indicate that BCSWL often face heightened role conflicts in workplace and family settings, compounded by a lack of adequate support. They are also particularly vulnerable to psychosocial pressures and stigmatization in romantic relationships. Despite these challenges, BCSWL demonstrate remarkable resilience, effectively navigating these difficulties across different relational contexts. Receiving support from relational networks throughout their lifelong treatment is crucial for their overall health and well-being.
期刊：
Archives of Gerontology and Geriatrics,2025年128:105622 ISSN：0167-4943
通讯作者：
Xinhong Yin
作者机构：
[Zhang, Hongtao; Zhou, Yutong; She, Keyi; Gao, Yue; Chen, Yao; Zhang, Wen] School of Nursing, University of South China, Hengyang, Hunan, PR China;[Zhou, Li; Jiang, Dandan] The Second Hospital, University of South China, Hengyang, Hunan, PR China;[Yin, Xinhong] School of Nursing, University of South China, Hengyang, Hunan, PR China. Electronic address: 466844009@qq.com
通讯机构：
[Xinhong Yin] S;School of Nursing, University of South China, Hengyang, Hunan, PR China
摘要：
Introduction Frailty is a geriatric syndrome that is highly susceptible to adverse health outcomes and is a major burden that exacerbates society's medical care. By investigating the frailty trajectory within the older demographic and initially recognizing its clinical outcomes, we will have more tactics to manage the at-risk population.
Frailty is a geriatric syndrome that is highly susceptible to adverse health outcomes and is a major burden that exacerbates society's medical care. By investigating the frailty trajectory within the older demographic and initially recognizing its clinical outcomes, we will have more tactics to manage the at-risk population.
Methods We executed a systematic review of trajectory studies elucidating the connection between frailty and adverse outcomes among older individuals (≥ 65 years) and explored articles published in English and Chinese from the inception of the database until Jun 30, 2024, in PubMed, Web of Science, Embase, The Cochrane Library, CINAHL, Scopus, CNKI, China Online Journals, VIP Information, and SinoMed.
We executed a systematic review of trajectory studies elucidating the connection between frailty and adverse outcomes among older individuals (≥ 65 years) and explored articles published in English and Chinese from the inception of the database until Jun 30, 2024, in PubMed, Web of Science, Embase, The Cochrane Library, CINAHL, Scopus, CNKI, China Online Journals, VIP Information, and SinoMed.
Results The database survey unearthed 3522 articles, of which 21 were deemed eligible. The majority incorporated distinct assessment tools and statistical methodologies to classify frailty trajectories into three groups. Although these frailty trajectories produced inconsistent clinical outcomes, they did reveal trends in the frailty status of older adults.
The database survey unearthed 3522 articles, of which 21 were deemed eligible. The majority incorporated distinct assessment tools and statistical methodologies to classify frailty trajectories into three groups. Although these frailty trajectories produced inconsistent clinical outcomes, they did reveal trends in the frailty status of older adults.
Conclusion The link between frailty trajectories and adverse outcome is a multifaceted and complex process that is currently understudied. More comprehensive and in-depth longitudinal studies should be conducted to explore the mechanism of interaction between the two to obstruct the progression of the frailty trajectory and bolster support for interventions.
The link between frailty trajectories and adverse outcome is a multifaceted and complex process that is currently understudied. More comprehensive and in-depth longitudinal studies should be conducted to explore the mechanism of interaction between the two to obstruct the progression of the frailty trajectory and bolster support for interventions.
