期刊论文

Yang, Jin;Chen, L

英文

ARCHIVES OF DERMATOLOGICAL RESEARCH

0340-3696

2025

317

1

1-15

10.1007/s00403-025-04120-2

The Project of Sichuan Medical Association, S22049, the Project of the Health Commission of Chengdu,2023128, National Natural Science Foundation of China, no. 82300869,no. 82300869, Natural Science Foundation from the Department of Science and Technology of Sichuan Province, no. 2022NSFSC1592, no. 2022NSFSC1592, the Chengdu University Affiliated Hospital Climbing Talent Program,the Innovation Team Project of the Affiliated Hospital of Clinical School of Medicine of Chengdu University, CDFYCX202207, CDFYCX202207, the Program of the Affiliated Hospital of Chengdu University, Y202204 and Y202207, Y202204 and Y202207, the Chengdu Medical Research Projects, 2022181 and 2023343, research projects from Chengdu Science and Technology, no. 2022-YF05-01441-SN, Sichuan Medical (Youth Innovative) Scientific Research Projects, nos. Q23002, S22002 and Q20013, the Teaching Reform Project of Chengdu University,cdjgb2022043, cdjgb2022166 and cdjgb2019005

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Hypertrophic scarring (HS) is a fibrotic skin disorder characterized by excessive deposition of extracellular matrix (ECM), leading to symptoms such as pain, itching, and skin contraction. HS can also result in restricted joint mobility and cosmetic deformities, imposing psychological and economic burdens on patients. Additionally, it increases wound care costs, and currently, no ideal treatment options exist. Therefore, HS is not only a clinical care issue but also a societal problem, with significant challenges related to its management and p...