期刊:
Sustainable Materials and Technologies,2021年27:e00229- ISSN:2214-9937
通讯作者:
Liu, Xuehua;Bi, Lei
作者机构:
[Cao, Ning; Liu, Xuehua; Xu, Yangsen; Xu, Xi] Qingdao Univ, Inst Mat Energy & Environm, Coll Mat Sci & Engn, Ningxia Rd 308, Qingdao 266071, Peoples R China.;[Bi, Lei] Univ South China, Sch Resource Environm & Safety Engn, Hengyang 421001, Peoples R China.
通讯机构:
[Liu, Xuehua] Q;[Bi, Lei] U;Qingdao Univ, Inst Mat Energy & Environm, Coll Mat Sci & Engn, Ningxia Rd 308, Qingdao 266071, Peoples R China.;Univ South China, Sch Resource Environm & Safety Engn, Hengyang 421001, Peoples R China.
关键词:
Electrocatalysts;Nitrogen reduction reaction;Defects;Density function theory (DFT)
摘要:
Electrochemical nitrogen (N-2) reduction has become as an energy-saving and eco-friendly alternative to Haber-Bosch processes for sustainable ammonia (NH3) synthesis at ambient. In recent years, the synthesis of NH3 from N-2 and water (H2O) in aqueous media is one of the most attractive topics in the field of electrochemistry. To date, to achieve both high catalytic performance and selectivity, the enhancement of activity is usually attributed to the high specific surface area, unique facet structure, enhanced conductivity, and even unclear synergistic effects. However, the importance of defects, especially intrinsic defects, is often overlooked. Recently, the importance of defects in electrocatalytic ammonia synthesis has been demonstrated, and the study on this aspect is becoming a hot topic in the field. In order to have an overview on the influence of defects on the performance of electrochemical synthesis of NH3, this paper introduces the latest development of the concept of using defects, including oxygen-vacancy defects, nitrogen-vacancy defects, sulfur-vacancy defects and carbon-vacancy defects, to enhance the performance of electrocatalytic nitrogen reduction reaction (NRR). Finally, the prospect of further pathways of designing catalysts for NRR with defect engineering is given. (C) 2020 Elsevier B.V. All rights reserved.
摘要:
It is an important challenge to develop a chemosensor for trace uranyl ion in an aqueousmediumfor sustainable development of nuclear energy and environmental conservation. A conjugated fluorescent polymer sensor P2 based on amidoxime groups and polyfluorene, which showed good hydrophilous resulting adequate contact with uranyl ions and selectivity and sensitivity even in the presence of other metal ions in DMA/H2O (v/v = 20:80, pH= 6.0) solution, for uranyl ion was designed and prepared in this work. And it possesses good thermal stability and a larger Stokes shift (108 nm). Importantly, the fluorescence quenching occurredwhen P2 combining uranium. It had a good linear relationship with UO22+ concentration in the range of 10 to 200 nM with a fairly low LOD 7.4 x 10(-9) M. Interaction properties between the sensor P2 and UO22+ and the fluorescent mechanism were investigated by density functional theory (DFT). More importantly, the sensor can be successfully used for the detection of uranyl ion in environmental solutions. This work suggests that conjugated fluorescent polymer with amidoxime groups will be a prospective sensor of uranyl ion in the environmental sample. (C) 2020 Elsevier B.V. All rights reserved.
摘要:
Microglia-associated neuroinflammation plays an important role in the pathophysiology of ischemic stroke. Microglial activation and polarization, and the inflammatory response mediated by these cells play important roles in the development, progression and outcome of brain injury after ischemic stroke. Currently, there is no effective strategy for treating ischemic stroke in clinical practice. Therefore, it is clinically important to study the role and regulation of microglia in stroke. In this review, we discuss the involvement of microglia in the neuroinflammatory process in ischemic stroke, with the aim of providing a better understanding of the relationship between ischemic stroke and microglia.
摘要:
Rationale: Siglec15 is an emerging target for normalization cancer immunotherapy. However, pan-cancer anti-Siglec15 treatment is not yet validated and the potential role of Siglec15 in bladder cancer (BLCA) remains elusive. Methods: We comprehensively evaluated the expression pattern and immunological role of Siglec15 using pan-cancer analysis based on RNA sequencing data obtained from The Cancer Genome Atlas. We then systematically correlated Siglec15 with immunological characteristics in the BLCA tumor microenvironment (TME), including immunomodulators, cancer immunity cycles, tumor-infiltrating immune cells (TIICs), immune checkpoints, and T cell inflamed score. We also analyzed the role of Siglec15 in predicting the molecular subtype and the response to several treatment options in BLCA. Our results were validated in several public cohorts as well as our BLCA tumor microarray cohort, the Xiangya cohort. We developed an immune risk score (IRS), validated it, and tested its ability to predict the prognosis and response to cancer immunotherapy. Results: We found that Siglec15 was specifically overexpressed in the TME of various cancers. We hypothesize that Siglec15 designs a non-inflamed TME in BLCA based on the evidence that Siglec15 negatively correlated with immunomodulators, TIICs, cancer immunity cycles, immune checkpoints, and T cell inflamed score. Bladder cancer with high Siglec15 expression was not sensitive to cancer immunotherapy, but exhibited a higher incidence of hyperprogression. High Siglec15 levels indicated a luminal subtype of BLCA characterized by lower immune infiltration, lower response to cancer immunotherapy and neoadjuvant chemotherapy, but higher response to anti-angiogenic therapy and targeted therapies such as blocking Siglec15, beta-catenin, PPAR-gamma, and FGFR3 pathways. Notably, a combination of anti-Siglec15 and cancer immunotherapy may be a more effective strategy than monotherapy. IRS can accurately predict the prognosis and response to cancer immunotherapy. Conclusions: Anti-Siglec15 immunotherapy might be suitable for BLCA treatment as Siglec15 correlates with a non-inflamed TME in BLCA. Siglec15 could also predict the molecular subtype and the response to several treatment options.
作者机构:
[Lv, Qi-Yan; Sun, Kai; Yu, Bing] Zhengzhou Univ, Coll Chem, Green Catalysis Ctr, Zhengzhou 450001, Peoples R China.;[Lv, Qi-Yan; He, Wei-Min] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Peoples R China.;[Lin, Ying-Wu] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.;[He, Wei-Min] Hunan Univ Sci & Engn, Dept Chem, Yongzhou 425100, Peoples R China.
通讯机构:
[Yu, Bing] Z;[He, Wei-Min] C;[He, Wei-Min] H;Zhengzhou Univ, Coll Chem, Green Catalysis Ctr, Zhengzhou 450001, Peoples R China.;Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Peoples R China.
摘要:
The cyano group is a valuable and readily available functional group for the preparation of various functional groups, such as amines, carboxylic acids, and ketones. In recent decades, the radical cascade reaction has emerged as a versatile tool to prepare a large variety of functional molecules. The application of the cyano group as a radical acceptor in cascade reactions provides diverse opportunities for the convenient construction of various important heterocycles and carbocycles. Such synthetic strategies will open new ways for the rapid buildup of molecular complexity. The focus of this review is the summary of the dynamic field of radical cascade processes using the cyano group as a radical acceptor, which has not been well documented so far.
摘要:
This article investigates quaternion-valued fuzzy cellular neural networks with delays. With the help of fixed point theory, exponential dichotomy of linear equations and related inequalities, some new sufficient conditions which guarantee the existence and global exponentially stability of pseudo almost periodic solutions to quaternion-valued fuzzy cellular neural networks with delays are established. Computer simulations are carried out to check the practicability of the obtained main results. So far, no researchers have investigated this topic. The derived results of this article are completely innovative and complement some earlier investigations to some degree. (c) 2020 Elsevier B.V. All rights reserved.
期刊:
IEEE Transactions on Transportation Electrification,2021年7(2):399-409 ISSN:2332-7782
通讯作者:
Liu, Longcheng;Wei, Zhongbao
作者机构:
[Bian, Xiaolei; Liu, Longcheng] KTH Royal Inst Technol, Dept Chem Engn, S-11428 Stockholm, Sweden.;[Wei, Zhongbao] Beijing Inst Technol, Sch Mech Engn, Natl Engn Lab Elect Vehicles, Beijing 100811, Peoples R China.;[He, Jiangtao; Yan, Fengjun] McMaster Univ, Dept Mech Engn, Hamilton, ON L8S 4L8, Canada.;[Liu, Longcheng] Univ South China, Sch Nucl Sci & Technol, Hengyang 421001, Peoples R China.
通讯机构:
[Liu, Longcheng] K;[Wei, Zhongbao] B;KTH Royal Inst Technol, Dept Chem Engn, S-11428 Stockholm, Sweden.;Beijing Inst Technol, Sch Mech Engn, Natl Engn Lab Elect Vehicles, Beijing 100811, Peoples R China.
关键词:
State of charge;Estimation;Batteries;Computational modeling;Mathematical model;Integrated circuit modeling;Transportation;Filter tuning;Kalman filter;lithium-ion battery;particle swarm optimization (PSO);state of charge (SOC)
摘要:
The state-of-charge (SOC) estimation is an enabling technique for the efficient management and control of lithium-ion batteries (LIBs). This article proposes a novel method for online SOC estimation, which manifests itself with both high accuracy and low complexity. Particularly, the particle swarm optimization (PSO) algorithm is exploited to optimize the model parameters to ensure high modeling accuracy. Following this endeavor, the PSO algorithm is used to tune the error covariances of extended Kalman filter (EKF) leveraging the early stage segmental data of LIB utilization. Within this PSO-based tuning framework, the searching boundary is derived by scrutinizing the error transition property of the system. Experiments are performed to validate the proposed two-step PSO-optimized SOC estimation method. Results show that even by using a simple first-order model, the proposed method can give rise to a high SOC accuracy, which is comparative to those using complex high-order models. The proposed method is validated to excavate fully the potential of model-based estimators so that the computationally expensive model upgrade can be avoided.
摘要:
An eco-friendly,sustainable and practical method for the efficient preparation of 5-organylselanyl uracils through the electrochemical selenylation of uracils and dio rganyl diselenides at room temperature under oxidant-and external electrolvte-free conditions was developed.
作者机构:
[Yu, B. X.; Dai, X. C.; Yu, G.; Hu, T.; Ning, Z.; Wen, S. P.; Shi, X.; Sun, G. X.; Ma, M. M.; Zhao, Ling; Zhu, Z. A.; Xu, G. F.; Wang, K.; Zhou, L. P.; Heng, Y. K.; Ji, Q.; Zhang, J. W.; Rong, G.; Guan, C. Y.; Zhou, Q.; Wang, Y. F.; Wang, L. L.; Lu, Y.; Ouyang, Q.; Ji, X. B.; Qian, S.; Dong, M. Y.; Zhang, Jiawei; Fang, S. S.; Chang, J. F.; Wang, Zongyuan; Liu, Z. A.; Ke, B. C.; Wu, J. F.; Sun, S. S.; Fu, C. D.; Lou, X. C.; Zhang, B. X.; Fu, Y.; Xing, T. Y.; Cao, G. F.; Xiao, Y. J.; Wu, L. H.; Zhao, Y. B.; Zheng, J. P.; Jiang, X. S.; Kiuchi, R.; Gu, M. H.; Lu, Y. P.; Dong, L. Y.; Yang, S. L.; Zhao, G.; Wu, L. J.; Yang, Yifan; Yuan, Y.; Lu, X. L.; Wu, Z.; Fang, Y.; Luo, X. L.; Ji, X. L.; Zhu, A. N.; Li, L. K.; Li, H. B.; Liang, H.; Huang, Y. P.; Liao, L. Z.; Zhang, J. Y.; Yin, J. H.; Liu, Huanhuan; Song, W. M.; Zhang, J. Z.; He, K. L.; Chen, G.; Ablikim, M.; Liu, C. X.; Chang, W. L.; Zhu, K.; Kurth, M. G.; Zhao, J. Z.; Mao, Z. P.; Zhao, Q.; Xiao, S. Y.; Lu, J. G.; Sun, H. K.; Chen, Y. B.; Wang, Z.; Liu, Fang; Zhao, J. Y.; Dong, J.; Liu, K.; Wang, H. P.; Yuan, C. Z.; Tang, G. Y.; Zhang, H. Y.; Chen, M. L.; Hou, Z. L.; Sun, Y. Z.; Liu, B. J.; Li, Ke; Zhu, K. J.; Liu, H. M.; Ma, H. L.; Sun, T.; Ye, M.; Xie, Y. G.; Lu, J. D.; Zou, B. S.; Chen, H. S.; Cao, N.; Deng, Z. Y.; Ma, Q. M.; Wang, Z. Y.; Cai, X.; Zhang, Y. H.; Ma, R. Q.; Shi, R. S.; Zou, J. H.; Zhang, Yao; Liu, J. Y.; Li, W. G.; Wang, Y. Q.; Mo, X. H.; Fang, J.; Ma, X. X.; Shen, X. Y.; Sun, Z. T.; Liu, T.; Ma, X. Y.; Hu, H. M.; Gong, W. X.; Xu, W.; Hu, Y.; Wang, Meng; Zhang, Jianyu; Li, F.; Pathak, A.; Yang, H. X.; Qin, Z. H.; Li, G.; Ping, R. G.; Qiu, J. F.; Dai, H. L.; Li, W. D.] Inst High Energy Phys, Beijing 100049, Peoples R China.;[Gu, S.; Yuan, L.; Qi, T. Y.] Beihang Univ, Beijing 100191, Peoples R China.;[Li, Lei] Beijing Inst Petrochem Technol, Beijing 102617, Peoples R China.;[Jaeger, S.; Fritsch, M.; Heinsius, F. H.; Zhang, J. Q.; Kuessner, M.; Pitka, A.; Pelizaeus, M.; Kopf, B.; Keshk, I. K.; Wollenberg, L.; Albrecht, M.; Holtmann, T.; Schnier, C.; Feldbauer, F.; Wiedner, U.; de Boer, R. B.; Kuemmel, M.; Li, J. Q.; Held, T.] Bochum Ruhr Univ, D-44780 Bochum, Germany.;[Briere, R. A.] Carnegie Mellon Univ, Pittsburgh, PA 15213 USA.
通讯机构:
[Ablikim, M.] I;Inst High Energy Phys, Beijing 100049, Peoples R China.
摘要:
We report a study of the processes of e(+)e(-) -> K+Ds- D*(0) and K+Ds* D-0 based on e(+)e(-) annihilation samples collected with the BESIII detector operating at BEPCII at five center-of-mass energies ranging from 4.628 to 4.698 GeV with a total integrated luminosity of 3.7 fb(-1). An excess of events over the known contributions of the conventional charmed mesons is observed near the D-s(-) D*(0) and D-s*(-) D-0 mass thresholds in the K+ recoil-mass spectrum for events collected at root s = 4.681 GeV. The structure matches a mass-dependent-width Breit-Wigner line shape, whose pole mass and width are determined as (3982.5(-2.6)(+1.8) +/- 2.1) MeV/c(2) and (12.8(-4.4)(+5.3) +/- 3.0) MeV, respectively. The first uncertainties are statistical and the second are systematic. The significance of the resonance hypothesis is estimated to be 5.3 sigma over the contributions only from the conventional charmed mesons. This is the first candidate for a charged hidden-charm tetraquark with strangeness, decaying into D-s(-) D*(0) and D-s*(-) D-0. However, the properties of the excess need further exploration with more statistics.
作者机构:
[Nie, Jianhui; Qin, Haiyang; Wang, Meng; Liu, Junkai; Huang, Weijin; Liang, Haoyu; Li, Tao; Li, Qianqian; Li, Xiaoyu; Wu, Jiajing; Zhang, Mengyi; Liu, Shuo; Nie, Lingling; Wang, Youchun; Liu, Huan; Zhang, Li; Zhao, Chenyan; Zhang, Yue; Wang, Haixin; Ding, Ruxia; Lu, Qiong] Natl Inst Food & Drug Control NIFDC, Inst Biol Prod Control, Div HIV AIDS & Sex Transmitted Virus Vaccines, 31 Huatuo St, Beijing 102629, Peoples R China.;[Nie, Jianhui; Qin, Haiyang; Wang, Meng; Liu, Junkai; Huang, Weijin; Liang, Haoyu; Li, Tao; Li, Qianqian; Li, Xiaoyu; Wu, Jiajing; Zhang, Mengyi; Liu, Shuo; Nie, Lingling; Wang, Youchun; Liu, Huan; Zhang, Li; Zhao, Chenyan; Zhang, Yue; Wang, Haixin; Ding, Ruxia; Lu, Qiong] WHO, Collaborating Ctr Standardizat & Evaluat Biol, 31 Huatuo St, Beijing 102629, Peoples R China.;[Shi, Yi] Chinese Acad Sci, Inst Microbiol, CAS Key Lab Pathogen Microbiol & Immunol, Beijing 100101, Peoples R China.;[Shen, Yuelei] Beijing Biocytogen Co Ltd, Beijing 101111, Peoples R China.;[Xie, Liangzhi] Sino Biol Inc, BDA, Beijing Antibody Res Key Lab, Bldg 9,Jing Dong Bei Technol Pk, Beijing 100176, Peoples R China.
通讯机构:
[Qu, X.] T;[Xu, W.] N;[Huang, W.; Wang, Y.] D;National Institute for Viral Disease Control and Prevention, China;Translational Medicine Institute, China
作者机构:
[He, Wei-Min; Jiang, Jun] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.;[Xiao, Fang] Cent South Univ, Xiangya Sch Publ Hlth, Changsha 410078, Peoples R China.;[Wang, Leyong] Nanjing Univ, Sch Chem & Chem Engn, Key Lab Mesoscop Chem MOE, Nanjing 210023, Peoples R China.
通讯机构:
[He, W.-M.] S;School of Chemistry and Chemical Engineering, China
关键词:
Green chemistry;Green solvent;Water;Solvent free;Purification
摘要:
Clean production, as an important part of green chemistry, has received great attention and considerable development in recent years. In this perspective article, we summarized some examples of (nearly) quantitative synthesis, clean separation and purification to emphasize clean production. These reactions were carried out by using eco-friendly solvents and the pure products could be easily obtained through clean procedures.
摘要:
Tailoring the electronic structure of the perovskite oxide could potentially allow dramatic improvements in the properties of cathode materials in proton-conducting solid oxide fuel cells (SOFCs). This has been demonstrated in the case of Mo-doped La0.5Sr0.5FeO3-delta, where the electronic structure of the La0.5Sr0.5FeO3-delta oxide has been changed with the Mo-doping, leading to a less strong metal-oxygen bond as well as a more active surface towards oxygen reduction. As a result, the more active oxygen atoms make the formation of oxygen vacancy and hydration that are critical for protonation more feasible. Furthermore, the electric field induced by Mo-doping provides an additional driving force for the movement of protons, accelerating the proton migrations in the oxide and thus improving the cathode performance. With the Mo-doped La0.5Sr0.5FeO3-delta as the cathode, a proton-conducting SOFC exhibits an impressive fuel cell output of 1174 mW cm(-2) at 700 degrees C that surpasses most of the cells using similar types of cathodes. This study not only provides a proper cathode material without involving cobalt and barium elements but also gives an understanding of the design of the cathode by tailoring the electronic structures.