作者:
Ablikim, M.;Achasov, M. N.;Adlarson, P.;Ahmed, S.;Albrecht, M.;...
期刊:
中国物理C,2020年44(4):I0001-I0004 ISSN:1674-1137
通讯作者:
Gradl, W.
作者机构:
[Yu, B. X.; Dai, X. C.; Wang, X. F.; Hu, T.; Sun, Z. J.; Guo, R. P.; Ning, Z.; Wen, S. P.; Shi, X.; Sun, G. X.; Ma, M. M.; Min, J.; Zhao, Ling; Zhu, Z. A.; Xu, G. F.; Wang, K.; Zhou, L. P.; Heng, Y. K.; Ji, Q.; Zhang, J. W.; Rong, G.; Zhou, Q.; Wang, Y. F.; Wang, L. L.; Jin, D. P.; Xiu, Q. L.; Lu, Y.; Ouyang, Q.; Kurth, M.; Ji, X. B.; Qian, S.; Dong, M. Y.; Fang, S. S.; Chang, J. F.; Wang, Zongyuan; Liu, Z. A.; Ke, B. C.; Liu, X. Y.; Sun, S. S.; Fu, C. D.; Lou, X. C.; Wang, Z. G.; Zhang, B. X.; Fu, Y.; Sun, X. H.; Xing, T. Y.; Cao, G. F.; Xiao, Y. J.; Wu, L. H.; Zhao, Y. B.; Gao, Q.; Zheng, J. P.; Zhang, B. Y.; Jiang, X. S.; Kiuchi, R.; Gu, M. H.; Lu, Y. P.; Dong, L. Y.; Yang, S. L.; Zhao, G.; Wu, L. J.; Yang, Yifan; Yuan, Y.; Wu, Z.; Fang, Y.; Luo, X. L.; Ji, X. L.; Zhu, A. N.; Li, L. K.; Li, H. B.; Zhuang, J.; Li, J. C.; Liang, H.; Zhang, Yang; Liao, L. Z.; Zhang, J. Y.; Wang, L. S.; Yin, J. H.; Liu, Huanhuan; Zhang, J. Z.; He, K. L.; Chen, G.; Xiong, X. A.; Chen, J. C.; Ablikim, M.; Liu, C. X.; Chang, W. L.; Zhu, K.; Kurth, M. G.; Zhao, J. Z.; Mao, Z. P.; Zhao, Q.; Xiao, S. Y.; Lu, J. G.; Chen, Y. B.; Niu, S. L.; Wang, Z.; Liu, Fang; Zhao, J. Y.; Dong, J.; Zhang, C. C.; Zhang, D. H.; Yuan, C. Z.; Tang, G. Y.; Zhang, H. Y.; Chen, M. L.; Hou, Z. L.; Sun, Y. Z.; Liu, B. J.; Li, Ke; Zhu, K. J.; Liu, H. M.; Ma, H. L.; Ye, M.; Xie, Y. G.; Lu, J. D.; Sheng, H. Y.; Song, X. Y.; Zou, B. S.; Chen, H. S.; Cao, N.; Deng, Z. Y.; Ma, Q. M.; Wang, Z. Y.; Zhao, T. C.; Cai, X.; Xu, L.; Zhang, Y. H.; An, F. F.; Zou, J. H.; Zhang, Yao; Liu, J. Y.; Li, W. G.; Mo, X. H.; Zhou, L.; Fang, J.; Meng, Wang; Ma, X. X.; Shen, X. Y.; Zhu, Y. S.; Li, X. N.; Sun, Z. T.; Liu, T.; Ma, X. Y.; Hu, H. M.; Gong, W. X.; Wang, P. L.; Zhang, J.; Xu, W.; Hu, Y.; Wang, B.; Li, F.; Zhang, K.; Tang, X.; Yang, H. X.; Qin, Z. H.; Li, G.; Ping, R. G.; Qiu, J. F.; Zhao, J. W.; Dai, H. L.; Li, W. D.] Inst High Energy Phys, Beijing 100049, Peoples R China.;[Yan, W. C.; Zhou, Xingyu; Shen, C. P.; Qi, T. Y.] Beihang Univ, Beijing 100191, Peoples R China.;[Li, Lei] Beijing Inst Petrochem Technol, Beijing 102617, Peoples R China.;[Fritsch, M.; Heinsius, F. H.; Zhang, J. Q.; Weber, T.; Mustafa, A.; Kuessner, M.; Pitka, A.; Richter, M.; Pelizaeus, M.; Kopf, B.; Keshk, I. K.; Qin, X. S.; Albrecht, M.; Sowa, C.; Feldbauer, F.; Wiedner, U.; Kuemmel, M.; Held, T.] Bochum Ruhr Univ, D-44780 Bochum, Germany.;[Bennett, J., V; Briere, R. A.] Carnegie Mellon Univ, Pittsburgh, PA 15213 USA.
通讯机构:
[Gradl, W.] J;Johannes Gutenberg Univ Mainz, Johann Joachim Becher Weg 45, D-55099 Mainz, Germany.
关键词:
MESON;HADRON;optimization
摘要:
There has recently been a dramatic renewal of interest in hadron spectroscopy and charm physics. This renaissance has been driven in part by the discovery of a plethora of charmonium-like XYZ states at BESIII and B factories, and the observation of an intriguing proton-antiproton threshold enhancement and the possibly related X(1835) meson state at BESIII, as well as the threshold measurements of charm mesons and charm baryons. We present a detailed survey of the important topics in tau-charm physics and hadron physics that can be further explored at BESIII during the remaining operation period of BEPCII. This survey will help in the optimization of the data-taking plan over the coming years, and provides physics motivation for the possible upgrade of BEPCII to higher luminosity.
摘要:
With the development of nuclear power, the negative environmental impact such as radioactive pollution has become an urgent issue to impede the utilization of nuclear energy. The construction of promising organic-inorganic hybrid materials is considered as an effective strategy for environmental remediation of radioactive contamination. In this work, two-dimensional transition metal carbide (MXene), an emerging inorganic layered material, has been successfully modified by carboxyl terminated aryl diazonium salt to both enhance its chelating ability to radionuclides and improve its water stability. The carboxyl functionalized Ti3C2Tx MXene (TCCH) shows excellent removal ability for U(VI) and Eu(III), evidenced by ultrafast adsorption kinetics (3 min), high maximum adsorption capacities (344.8 mg/g for U and 97.1 mg/g for Eu) and high removal percentage of radionuclides from artificial groundwater (> 90%). The adsorption of U(VI) and Eu(III) on TCCH are in good accord with the Langmuir adsorption isotherm model and the pseudo-second-order kinetic model. Ionic strength experiments, X-ray photoelectron spectroscopy (XPS) and Extended X-ray absorption fine structure (EXAFS) analyses were conducted to assess the detailed adsorption mechanism. The results reveal that the adsorption of U(VI) on TCCH follows an inner-sphere configuration, whereas the adsorption of Eu(III) is determined by both inner-sphere complexation and electrostatic interaction.
作者机构:
[Duan, Chongxiong] Foshan Univ, Sch Mat Sci & Energy Engn, Foshan 528231, Peoples R China.;[Yu, Yi; Xi, Hongxia; Zhang, Xuelian; Li, Libo; Xiao, Jing] South China Univ Technol, Sch Chem & Chem Engn, Guangzhou 510640, Peoples R China.;[Wu, Junliang] South China Univ Technol, Sch Environm & Energy, Guangzhou 510006, Peoples R China.;[Yang, Pengfei] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.
通讯机构:
[Xi, Hongxia; Wu, Junliang] S;South China Univ Technol, Sch Chem & Chem Engn, Guangzhou 510640, Peoples R China.;South China Univ Technol, Sch Environm & Energy, Guangzhou 510006, Peoples R China.
关键词:
metal-organic frameworks;water-based routes;industrial Production
摘要:
Although metal-organic frameworks (MOFs) show numerous advantages over other crystalline materials, their industrial relevances have been impeded owing to their many drawbacks such as environmental impacts and economic costs of their synthesis. A green preparation pathway could greatly reduce the environmental costs, energy, and the need for toxic organic solvents, and consequently reduce the production cost. Thus, the most desirable synthesis route is the replacement of harsh organic solvents with aqueous solutions to abate environmental and economic impacts. This review summarizes recent research advancements of water-based routes for MOF synthesis and gives a brief outline of the most prominent examples. The challenges and prospects of the commercialization of promising MOFs in the future are also presented. This study aims to offer necessary information regarding the green, sustainable, and industrially acceptable fabrication of MOFs for their commercial applications in the future.
摘要:
Polycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine disease characterized by clinical or laboratorial hyperandrogenism, oligo-anovulation and metabolic abnormalities, including insulin resistance, excessive weight or obesity, type II diabetes, dyslipidemia and an increased risk of cardiovascular disease. The most significant clinical manifestation of PCOS is hyperandrogenism. Excess androgen profoundly affects granulosa cell function and follicular development via complex mechanisms that lead to obesity and insulin resistance. Most PCOS patients with hyperandrogenism have steroid secretion defects that result in abnormal folliculogenesis and failed dominant follicle selection. Hyperandrogenism induces obesity, hairy, acne, and androgenetic alopecia. These symptoms can bring great psychological stress to women. Drugs such as combined oral contraceptive pills, metformin, pioglitazone and low-dose spironolactone help improve pregnancy rates by decreasing androgen levels in vivo. Notably, PCOS is heterogeneous, and hyperandrogenism is not the only pathogenic factor. Obesity and insulin resistance aggravate the symptoms of hyperandrogenism, forming a vicious cycle that promotes PCOS development. Although numerous studies have been conducted, the definitive pathogenic mechanisms of PCOS remain uncertain. This review summarizes and discusses previous and recent findings regarding the relationship between hyperandrogenism, insulin resistance, obesity and PCOS.
摘要:
Sintering aids are often used in the fabrication of proton-conducting oxides to facilitate their application in solid oxide cells, but the detrimental effects of sintering aids on electrochemical performance have been noted in early studies. However, the landscape has changed as some recent studies have suggested that overall electrochemical performance is actually enhanced by using sintering aids, making this an important topic for debate. This mini review presents a discussion of the influence of sintering aids on the electrochemical performance of proton-conducting oxides, considering older studies as well as more recent results. The merits and challenges of sintering-aid-modified proton-conducting oxides are discussed.
关键词:
Carbon nanomaterials;Phonon;Thermal transport
摘要:
The diversity of thermal transport properties in carbon nanomaterials enables them to be used in different thermal fields such as heat dissipation, thermal management, and thermoelectric conversion. In the past two decades, much effort has been devoted to study the thermal conductivities of different carbon nanomaterials. In this review, different theoretical methods and experimental techniques for investigating thermal transport in nanosystems are first summarized. Then, the thermal transport properties of various pure carbon nanomaterials including 1D carbon nanotubes, 2D graphene, 3D carbon foam, are reviewed in details and the associated underlying physical mechanisms are presented. Meanwhile, we discuss several important influences on the thermal conductivities of carbon nanomaterials, including size, structural defects, chemisorption and strain. Moreover, we introduce different nanostructuring pathways to manipulate the thermal conductivities of carbon-based nanocomposites and focus on the wave nature of phonons for controlling thermal transport. At last, we briefly review the potential applications of carbon nanomaterials in the fields of thermal devices and thermoelectric conversion.
摘要:
By using ambient air as the oxidant and malic acid as the promoter, a practical method for the preparation of 2-aminobenzothiazoles through visible-light-initiated cascade reaction of aromatic amines and KSCN in eco-friendly bis(methoxypropy)ether under metal-, hazardous additive-, photocatalyst-free conditions was established.
期刊:
Applied Microbiology and Biotechnology,2020年104(2):575-587 ISSN:0175-7598
通讯作者:
Zhang, Ji;Liu, Jing
作者机构:
[Ou, Daming; Xu, Zhenru; Zhang, Ji; Liu, Ting] Univ South China, Affiliated Hosp 1, Dept Rheumatol, Hengyang, Hunan, Peoples R China.;[Liu, Jing; Han, Xu] Cent S Univ, Sch Life Sci, Mol Biol Res Ctr, Changsha, Hunan, Peoples R China.;[Liu, Jing; Han, Xu] Cent S Univ, Sch Life Sci, Ctr Med Genet, Changsha, Hunan, Peoples R China.;[Li, Zunxiong] Univ South China, Hengyang, Hunan, Peoples R China.;[Jiang, Guanmin] Sun Yat Sen Univ, Affiliated Hosp 1, Dept Clin Lab, Zhuhai, Guangdong, Peoples R China.
通讯机构:
[Zhang, Ji] U;[Liu, Jing] C;Univ South China, Affiliated Hosp 1, Dept Rheumatol, Hengyang, Hunan, Peoples R China.;Cent S Univ, Sch Life Sci, Mol Biol Res Ctr, Changsha, Hunan, Peoples R China.;Cent S Univ, Sch Life Sci, Ctr Med Genet, Changsha, Hunan, Peoples R China.
摘要:
Autophagy is a highly conserved catabolic process and participates in a variety of cellular biological activities. The phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway, as a critical regulator of autophagy, is involved in the initiation and promotion of a series of pathological disorders including various tumors. Autophagy also participates in regulating the balance between the tumor and the tumor microenvironment. Natural products have been considered a treasure of new drug discoveries and are of great value to medicine. Mounting evidence has suggested that numerous natural products are targeting PI3K/AKT/mTOR-mediated autophagy, thereby suppressing tumor growth. Furthermore, autophagy plays a "double-edged sword" role in different tumors. Targeting PI3K/AKT/mTOR-mediated autophagy is an important therapeutic strategy for a variety of tumors, and plays important roles in enhancing the chemosensitivity of tumor cells and avoiding drug resistance. Therefore, we summarized the roles of PI3K/AKT/mTOR-mediated autophagy in tumorigenesis, progression, and drug resistance of tumors, which may be utilized to design preferably therapeutic strategies for various tumors.
期刊:
International Journal of Antimicrobial Agents,2020年55(5):105951 ISSN:0924-8579
通讯作者:
Tang, Chao-Ke;Tang, Shi-Lin
作者机构:
[Tang, Chao-Ke; Liu, Shang-Ming; Li, Heng; Tang, Shi-Lin] Univ South China, Affiliated Hosp 1, Hengyang Med Coll,Dept Intens Care Unit,Hunan Pro, Med Res Expt Ctr,Inst Cardiovasc Dis,Key Lab Arte, Hengyang 421001, Hunan, Peoples R China.;[Yu, Xiao-Hua] Hainan Med Univ, Inst Clin Med, Affiliated Hosp 2, Haikou 460106, Hainan, Peoples R China.;[Tang, Chao-Ke] Univ South China, Inst Cardiovasc Dis, Hengyang 421001, Hunan, Peoples R China.;[Tang, Shi-Lin] Univ South China, Dept Intens Care Unit, Affiliated Hosp 1, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Tang, Chao-Ke; Tang, Shi-Lin] U;Univ South China, Affiliated Hosp 1, Hengyang Med Coll,Dept Intens Care Unit,Hunan Pro, Med Res Expt Ctr,Inst Cardiovasc Dis,Key Lab Arte, Hengyang 421001, Hunan, Peoples R China.;Univ South China, Inst Cardiovasc Dis, Hengyang 421001, Hunan, Peoples R China.;Univ South China, Dept Intens Care Unit, Affiliated Hosp 1, Hengyang 421001, Hunan, Peoples R China.
摘要:
Coronavirus disease 2019 (COVID-19) originated in the city of Wuhan, Hubei Province, Central China, and has spread quickly to 72 countries to date. COVID-19 is caused by a novel coronavirus, named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [previously provisionally known as 2019 novel coronavirus (2019-nCoV)]. At present, the newly identified SARS-CoV-2 has caused a large number of deaths with tens of thousands of confirmed cases worldwide, posing a serious threat to public health. However, there are no clinically approved vaccines or specific therapeutic drugs available for COVID-19. Intensive research on the newly emerged SARS-CoV-2 is urgently needed to elucidate the pathogenic mechanisms and epidemiological characteristics and to identify potential drug targets, which will contribute to the development of effective prevention and treatment strategies. Hence, this review will focus on recent progress regarding the structure of SARS-CoV-2 and the characteristics of COVID-19, such as the aetiology, pathogenesis and epidemiological characteristics. (C) 2020 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.
作者机构:
[Qiao, Yuchen; Quan, Meina; Fu, Yue; Zhao, Tan; Jia, Longfei; Tang, Yi; Qin, Qi; Jia, Jianping; Li, Yan; Wei, Cuibai; Wang, Fen] Capital Med Univ, Dept Neurol, Xuanwu Hosp, Innovat Ctr Neurol Disorders, Beijing 100053, Peoples R China.;[Jia, Jianping] Beijing Key Lab Geriatr Cognit Disorders, Beijing, Peoples R China.;[Jia, Jianping] Capital Med Univ, Clin Ctr Neurodegenerat Dis & Memory Impairment, Beijing, Peoples R China.;[Jia, Jianping] Beijing Inst Brain Disorders, Ctr Alzheimers Dis, Beijing, Peoples R China.;[Shi, Shengliang] Guangxi Med Univ, Affiliated Hosp2, Dept Neurol, Nanning, Peoples R China.
通讯机构:
[Jia, Jianping] C;Capital Med Univ, Dept Neurol, Xuanwu Hosp, Innovat Ctr Neurol Disorders, Beijing 100053, Peoples R China.
摘要:
China has the largest population of patients with dementia in the world, imposing a heavy burden on the public and health care systems. More than 100 epidemiological studies on dementia have been done in China, but the estimates of the prevalence and incidence remain inconsistent because of the use of different sampling methods. Despite improved access to health services, inadequate diagnosis and management for dementia is still common, particularly in rural areas. The Chinese Government issued a new policy to increase care facilities for citizens older than 65 years, but most patients with dementia still receive care at home. Western medicines for dementia symptoms are widely used in China, but many patients choose Chinese medicines even though they have little evidence supporting efficacy. The number of clinical trials of Chinese and western medicines has substantially increased as a result of progress in research on new antidementia drugs but international multicentre studies are few in number. Efforts are needed to establish a national system of dementia care enhance training in dementia for health professionals, and develop global collaborations to prevent and cure this disease.
摘要:
The safety and stability of roadways is greatly influenced by the complex geological conditions present in the Sanmenxia Bauxite Mine, Henan Province, China. In this study, based on data from field survey, advanced detection methods, numerical studies, and monitoring studies, we have adopted the method of steel fiber-reinforced shotcrete to improve the excavation rate of roadways and guarantee the safety of the tunnel when it passes through unfavorable geological bodies, such as shale rocks and broken argillaceous limestone. Field surveys showed that the stability of roof rocks is the major problem faced by engineers; however, tunnel construction using cast-in-situ concrete, which is the method currently applied, costs too much time, resulting in an excavation rate that is too slow to meet the requirements of the Sanmenxia Bauxite Mine. Here, we propose an optimized scheme which, when combined with numerical simulations and data from advanced detection techniques and field monitoring surveys, can improve the efficiency of roadway roof support. During the implementation of the new scheme, the geological anomalies ahead of the working face were detected in advance. It is assumed that the supporting effect of the steel fiber-reinforced shotcrete is equivalent to that of the cast-in-situ concrete as long as a certain thickness is reached. Moreover, the steel fiber-reinforced shotcrete has better mechanical properties than cast-in-situ concrete and achieves a better combination effect with surrounding rock masses. Based on geological conditions and numerical results, the shotcrete should be thickest in the middle area along the roadway axis passing through the unfavorable geological bodies, and gradually become less thick from the middle to both ends. Field tests were carried out to verify the effectiveness of the scheme. The monitoring results show that the roadway passing through broken argillaceous limestone was stable after being supported by shotcrete (at least 80 mm); its thickness should reach at least about 120 mm when passing through shale rock mass. The results indicate that the use of steel fiber-reinforced shotcrete can considerably shorten the construction time compared with cast-in-situ concrete support. The scheme has proved to be a feasible, economical, and time-saving method for underground excavation in the Sanmenxia Bauxite Mine.