作者机构：
[Wang XiaoLiang; Liu YaLan; Wang YanFei] Univ S China, Sch Chem & Chem Engn, Dept Appl Chem, Hengyang 421001, Peoples R China.;[Li ZiJie; Lan JianHui; Wang XiaoLiang; Yuan LiYong; Zhao YuLiang; Liu YaLan; Feng YiXiao; Shi WeiQun; Chai ZhiFang] Chinese Acad Sci, Inst High Energy Phys, Key Lab Nucl Analyt Techn, Beijing 100049, Peoples R China.;[Li ZiJie; Lan JianHui; Yuan LiYong; Zhao YuLiang; Feng YiXiao; Shi WeiQun] Chinese Acad Sci, Inst High Energy Phys, Key Lab Biomed Effects Nanomat Nanosafety, Beijing 100049, Peoples R China.
通讯机构：
[Wang YanFei] U;Univ S China, Sch Chem & Chem Engn, Dept Appl Chem, Hengyang 421001, Peoples R China.
作者机构：
[周继承; 阳鹏飞; 王哲] Key Laboratory of Green Catalysis and Chemical Reaction Engineering in College of Hunan Province, School of Chemistry and Chemical Engineering, Xiangtan University, Xiangtan 411105, China;[阳鹏飞] School of Chemistry and Chemical Engineering, University of South China, Hengyang 421001, China
作者机构：
[戚晓燕; 吴红枚] Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, University of South China, Hengyang 421001, China;[赵宇亮; 石伟群; 冯一潇; 戚晓燕; 袁立永; 柴之芳] Institute of High Energy Physics, China Academy of Sciences, Beijing 100049, China
通讯机构：
Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, University of South China, China
摘要：
Metallic oxide/carbon composite has been extensively studied and widely used for energy storage in supercapacitor and lithium ion battery. In this paper, we synthesized nanograins-grafted nanorods of MoO2/carbon composites through a facile chemical reaction process without any template. Well crystallized MoO2 with monoclinic structure was identified in the XRD pattern. MoO2 nanograins with the size of 30-50nm were grown on the carbon nanorods, which were a few microns in length. Coupling of the rods-like carbon with good conductivity and the well distributed redox-active MoO2 leads to improved electrochemical performance. The cyclic voltammogram measurement shows that the as-prepared nanocomposites exhibit a broad potential window of 1.3V, which is extremely desired for supercapacitor application. The symmetrical supercapacitor of the nanograins-grafted nanorods of MoO2/carbon composites can work even at a high electric potential of 1.2V in aqueous electrolyte which seems impossible for many other metallic oxide and carbon composites.
摘要：
The biological toxicity of uranyl ion (UO
2
2+
) lies in interacting with proteins and disrupting their native functions. The structural and functional consequences of UO
2
2+
interacting with cytochrome b
5 (cyt b
5), a small membrane heme protein, and its heme axial ligand His39Ser variant, cyt b
5 H39S, were investigated both experimentally and theoretically. In experiments, although cyt b
5 was only slightly affected, UO
2
2+
binding to cyt b
5 H39S with a K
D of 2.5 μM resulted in obvious alteration of the heme active site, and led to a decrease in peroxidase activity. Theoretically, molecular simulation proposed a uranyl ion binding site for cyt b
5 at surface residues of Glu37 and Glu43, revealing both coordination and hydrogen bonding interactions. The information gained in this study provides insights into the mechanism of uranyl toxicity toward membrane protein at an atomic level.
摘要：
A novel small molecule probe, aptamer beacon (AB), was introduced for adenosine (Ade) recognition and quantitative analysis. The Ade aptamer was engineered into an aptamer beacon by adding a gold nanoparticle-modified nucleotide sequence which is complementary to aptamer sequence (FDNA) at the 3'-end of FDNA. The fluorescence signal "turning on" was observed when AB was bound to Ade, which is attributed to a significant conformational change in AB from a FDNA/QDNA duplex to a FDNA-Ade complex. The Ade measurement was carried out in 20 mmol L-1 Tris-HCl buffer solution of pH 7.4, Delta F signal linearly correlated with the concentration of Ade over the range of 2.0 x 10(-8) to 1.8 x 10(-6) mol L-1. The limit of detection (LOD) for Ade is 6.0 x 10(-9) mol L-1 with relative standard deviations (R.S.D) of 3.64-5.36%, and the recoveries were 98.6%, 100%, 102% (n = 6), respectively. The present method has been successfully applied to determine Ade in human urine samples, and the obtained results were in good agreement with those obtained by the HPLC method. Our investigation shows that the unique properties of the AB could provide a promising potential for small molecules detection, and be benefit to extend the application of aptamer beacon technique. (C) 2012 Elsevier B.V. All rights reserved.
作者：
Ling, H. -y.;Hu, B.;Hu, X. -b.;Zhong, J.;Feng, S. -d.;...
期刊：
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES,2012年120(9):553-559 ISSN：0947-7349
通讯作者：
Liao, D. -f.
作者机构：
[Ling, H. -y.; Hu, B.] Univ S China, Sch Med, Dept Physiol, Hengyang, Peoples R China.;[Liao, D. -f.] Hunan Univ Chinese Med, State Key Lab Chinese Med Powder & Med Innovat Hu, Div Stem Cell Regulat & Applicat, Changsha 410208, Hunan, Peoples R China.;[Ling, H. -y.] Univ S China, Ctr Basic Med Postdoctoral Studies, Hengyang, Peoples R China.;[Hu, X. -b.] Univ S China, Sch Life Sci & Technol, Dept Biochem & Mol Biol, Hengyang, Peoples R China.;[Wen, G. -b.; Zhong, J.] Univ S China, Affiliated Hosp 1, Inst Clin Res, Hengyang, Peoples R China.
通讯机构：
[Liao, D. -f.] H;Hunan Univ Chinese Med, State Key Lab Chinese Med Powder & Med Innovat Hu, Div Stem Cell Regulat & Applicat, Changsha 410208, Hunan, Peoples R China.
作者机构：
[杨雨山; 彭国文] School of Resources and Safety Engineering, Central South University, Changsha 410083, China;[王晓亮; 彭国文] School of Chemistry and Chemical Engineering, University of South China, Hengyang 421001, China;[杨雨山; 彭国文; 胡南; 丁德馨] Key Discipline Lab. for National Defence for Biotechnology in Uranium Mining and Hydrometallurgy, University of South China, Hengyang 421001, China
通讯机构：
Key Discipline Lab. for National Defence for Biotechnology in Uranium Mining and Hydrometallurgy, University of South China, China
期刊：
CHEMICAL SOCIETY REVIEWS,2012年41(2):797-828 ISSN：0306-0012
通讯作者：
Wang, Guoping
作者机构：
[Wang, Guoping] Univ S China, Coll Chem Engn, Hengyang 421001, Peoples R China.;[Zhang, Jiujun; Zhang, Lei; Wang, Guoping] Natl Res Council Canada, Inst Fuel Cell Innovat, Vancouver, BC V6T 1W5, Canada.
通讯机构：
[Wang, Guoping] U;Univ S China, Coll Chem Engn, Hengyang 421001, Peoples R China.
摘要：
In this critical review, metal oxides-based materials for electrochemical supercapacitor (ES) electrodes are reviewed in detail together with a brief review of carbon materials and conducting polymers. Their advantages, disadvantages, and performance in ES electrodes are discussed through extensive analysis of the literature, and new trends in material development are also reviewed. Two important future research directions are indicated and summarized, based on results published in the literature: the development of composite and nanostructured ES materials to overcome the major challenge posed by the low energy density of ES (476 references).
