期刊：
Journal of Cranio-Maxillofacial Surgery,2025年53(5):576-589 ISSN：1010-5182
通讯作者：
Chen, J
作者机构：
[Qiu, Xiaohui] Cent South Univ, Xiangya Hosp, Natl Clin Res Ctr Geriatr Disorders, Changsha, Peoples R China.;[Chen, Jing] Cent South Univ, Xiangya Hosp, Dept Neurosurg, Changsha, Peoples R China.;[Zhou, Jianda; Qiu, Xiaohui; Zhong, Chi] Cent South Univ, Xiangya Hosp 3, Dept Plast & Reconstruct Surg, Changsha, Peoples R China.;[Chen, Qiuyang; Liao, Shenghui] Cent South Univ, Sch Comp Sci, Changsha, Peoples R China.;[Yang, Tong; Zhao, Yingchao] Univ South China, Sch Mech Engn, Hengyang, Peoples R China.
通讯机构：
[Chen, J ] C;Cent South Univ, Xiangya Hosp, Dept Neurosurg, Changsha, Peoples R China.
关键词：
Artificial intelligence;CT big dataset;Surgical design
摘要：
Background The morphology of the zygomatic complex significantly influences facial appearance, leading to a focus on zygomatic osteotomy. The current technique, the “L-shaped” zygomatic osteotomy, requires a small incision and preoperative osteotomy design for an osteotomy guide. However, the use of multiple software programs in the design process makes it time-consuming and clinically challenging.
The morphology of the zygomatic complex significantly influences facial appearance, leading to a focus on zygomatic osteotomy. The current technique, the “L-shaped” zygomatic osteotomy, requires a small incision and preoperative osteotomy design for an osteotomy guide. However, the use of multiple software programs in the design process makes it time-consuming and clinically challenging.
Method Artificial intelligence technology offers a solution by integrating digital medical technology into medicine. AI algorithms were developed based on point cloud models, using 2000 cases of three-dimensional CT data for training. Eighty CT data sets were randomly chosen for both AI and manual skull segmentation designs. The effectiveness, symmetry, safety, and aesthetic outcomes were compared.
Artificial intelligence technology offers a solution by integrating digital medical technology into medicine. AI algorithms were developed based on point cloud models, using 2000 cases of three-dimensional CT data for training. Eighty CT data sets were randomly chosen for both AI and manual skull segmentation designs. The effectiveness, symmetry, safety, and aesthetic outcomes were compared.
Result The AI zygomatic osteotomy showed superior performance in symmetry and aesthetics compared to manual zygomatic osteotomy. The complex structure of the zygomatic arch highlights the advantages of AI-driven osteotomy design, especially in intricate cases. Additionally, the AI osteotomy scheme demonstrated no compromise in safety indicators compared to the manual approach.
The AI zygomatic osteotomy showed superior performance in symmetry and aesthetics compared to manual zygomatic osteotomy. The complex structure of the zygomatic arch highlights the advantages of AI-driven osteotomy design, especially in intricate cases. Additionally, the AI osteotomy scheme demonstrated no compromise in safety indicators compared to the manual approach.
Conclusion AI zygomatic osteotomy proves to be a safe and effective alternative to manual zygomatic osteotomy, showcasing enhanced symmetry and aesthetic outcomes. The efficiency and precision of AI-driven design in complex zygomatic osteotomies make it a promising advancement in this field.
AI zygomatic osteotomy proves to be a safe and effective alternative to manual zygomatic osteotomy, showcasing enhanced symmetry and aesthetic outcomes. The efficiency and precision of AI-driven design in complex zygomatic osteotomies make it a promising advancement in this field.
摘要：
The significance of biomedical applications of bio-functional niobium (Nb)-based metallic biomaterials is underscored by their potential utilization in implant application. Nb-based metallic materials present reliable physicomechanical and biological properties, thus represent materials highly suitable for implant application. This review provides an overview on the advances of pure niobium and Nb-based metallic materials as implant materials over the past 20 years, and highlights the advantages of Nb-based metallic biomaterials for implant application in terms of their physicomechanical properties, corrosion resistance in biological media, magnetic resonance imaging (MRI) compatibility, cell compatibility, blood compatibility, osteogenesis, and bioactivity. An introduction is provided for the production and processing techniques for Nb-based metallic biomaterials, including traditional melting processes like vacuum arc remelting, additive manufacturing like selective laser melting (SLM), electron beam melting (EBM), spark plasma sintering (SPS), and severe plastic deformation like equal channel angular pressing (ECAP), multi-axial forging (MAF), high pressure torsion (HPT), as well as their physicomechanical properties and implant application. Also suggested are the critical issues, challenges, and prospects in the further development of Nb-based metallic biomaterials for implant applications.
The significance of biomedical applications of bio-functional niobium (Nb)-based metallic biomaterials is underscored by their potential utilization in implant application. Nb-based metallic materials present reliable physicomechanical and biological properties, thus represent materials highly suitable for implant application. This review provides an overview on the advances of pure niobium and Nb-based metallic materials as implant materials over the past 20 years, and highlights the advantages of Nb-based metallic biomaterials for implant application in terms of their physicomechanical properties, corrosion resistance in biological media, magnetic resonance imaging (MRI) compatibility, cell compatibility, blood compatibility, osteogenesis, and bioactivity. An introduction is provided for the production and processing techniques for Nb-based metallic biomaterials, including traditional melting processes like vacuum arc remelting, additive manufacturing like selective laser melting (SLM), electron beam melting (EBM), spark plasma sintering (SPS), and severe plastic deformation like equal channel angular pressing (ECAP), multi-axial forging (MAF), high pressure torsion (HPT), as well as their physicomechanical properties and implant application. Also suggested are the critical issues, challenges, and prospects in the further development of Nb-based metallic biomaterials for implant applications.
Statement of significance Nb-based biomaterials have gained significant interest for bioimplantable scaffolds because of their appropriate mechanical characteristics and biocompatibility. No prior work has been published specifically reviewing bio-functional Nb-based biomaterials for exploring their physicomechanical properties, biological significance, and implant applications. This review provides an overview on the advances of niobium and Nb-based materials as implant materials over the past 20 years, and highlights the advantages of Nb-based biomaterials for implant application. An introduction is provided for the production and processing techniques for Nb-based biomaterials, as well as their physicomechanical properties and implant application. Also suggested are the critical issues, challenges, and prospects in the further development of Nb-based biomaterials for implant applications.
Nb-based biomaterials have gained significant interest for bioimplantable scaffolds because of their appropriate mechanical characteristics and biocompatibility. No prior work has been published specifically reviewing bio-functional Nb-based biomaterials for exploring their physicomechanical properties, biological significance, and implant applications. This review provides an overview on the advances of niobium and Nb-based materials as implant materials over the past 20 years, and highlights the advantages of Nb-based biomaterials for implant application. An introduction is provided for the production and processing techniques for Nb-based biomaterials, as well as their physicomechanical properties and implant application. Also suggested are the critical issues, challenges, and prospects in the further development of Nb-based biomaterials for implant applications.
摘要：
Ultrasound (US) images have the advantages of no radiation, high penetration, and real-time imaging, and optical coherence tomography (OCT) has the advantage of high resolution. The purpose of fusing endometrial images from optical coherence tomography (OCT) and ultrasound (US) is to combine the advantages of different modalities to ultimately obtain more complete information on endometrial thickness. To better integrate multimodal images, we first proposed a Symmetric Dual-branch Residual Dense (SDRD-Net) network for OCT and US endometrial image fusion. Firstly, using Multi-scale Residual Dense Blocks (MRDB) to extract shallow features of different modalities. Then, the Base Transformer Module (BTM) and Detail Extraction Module (DEM) are used to extract primary and advanced features. Finally, the primary and advanced features are decomposed and recombined through the Feature Fusion Module (FMM), and the fused image is output. We have conducted experiments across both private and public datasets, encompassing IVF and MIF tasks, achieving commendable results.
Ultrasound (US) images have the advantages of no radiation, high penetration, and real-time imaging, and optical coherence tomography (OCT) has the advantage of high resolution. The purpose of fusing endometrial images from optical coherence tomography (OCT) and ultrasound (US) is to combine the advantages of different modalities to ultimately obtain more complete information on endometrial thickness. To better integrate multimodal images, we first proposed a Symmetric Dual-branch Residual Dense (SDRD-Net) network for OCT and US endometrial image fusion. Firstly, using Multi-scale Residual Dense Blocks (MRDB) to extract shallow features of different modalities. Then, the Base Transformer Module (BTM) and Detail Extraction Module (DEM) are used to extract primary and advanced features. Finally, the primary and advanced features are decomposed and recombined through the Feature Fusion Module (FMM), and the fused image is output. We have conducted experiments across both private and public datasets, encompassing IVF and MIF tasks, achieving commendable results.
作者机构：
[唐鹏; 唐虎; 易礼杨; 李必文] School of Mechanical Engineering, University of South China, Hengyang 421001, Hunan, China;[谭文甫] Department of Orthopaedics Trauma, the Second Affiliated Hospital of University of South China, Hengyang 421001, Hunan, China
摘要：
The coating of mesoporous silica nanoshells can improve the stability of gold nanorods while improving the corresponding drug‐carrying capacity. Mesoporous silica coated gold nanorod (GNR@MSN) provides the opportunity to integrate different treatments into a single nanoplatform combining cancer treatment with real‐time diagnosis. This review discusses the advancements of GNR@MSN in synthetic process, bio‐imaging techniques and tumor therapy. Abstract For unique surface plasmon absorption and fluorescence characteristics, gold nanorods have been developed and widely employed in the biomedical field. However, limitations still exist due their low specific surface area, instability and tendency agglomerate in cytoplasm. Mesoporous silica materials have been broadly applied in field of catalysts, adsorbents, nanoreactors, and drug carriers due to its unique mesoporous structure, highly comparative surface area, good stability and biocompatibility. Therefore, coating gold nanorods with a dendritic mesopore channels can effectively prevent particle agglomeration, while increasing the specific surface area and drug loading efficiency. This review discusses the advancements of GNR@MSN in synthetic process, bio‐imaging technique and tumor therapy. Additionally, the further application of GNR@MSN in imaging‐guided treatment modalities is explored, while its promising superior application prospect is highlighted. Finally, the issues related to in vivo studies are critically examined for facilitating the transition of this promising nanoplatform into clinical trials.
作者：
Su, Chi;Hua, Yilong;Liu, Yi;Tao, Shu;Jia, Fei;...
期刊：
PLOS ONE,2024年19(3):e0300800 ISSN：1932-6203
通讯作者：
Lin, WY
作者机构：
[Hua, Yilong; Liu, Yi; Su, Chi; Zhao, Wenhui] Univ South China, Sch Resources Environm & Safety Engn, Hengyang 421001, Peoples R China.;[Tao, Shu] Univ South China, Sch Math & Phys, Hengyang, Peoples R China.;[Jia, Fei] Univ South China, Sch Civil Engn, Hengyang, Peoples R China.;[Zhao, Wenhui] Shanxi Prov Changzhi City Wuxiang Cty Jia Huo Town, Changzhi, Peoples R China.;[Lin, WY; Lin, Wangyang] Univ South China, Coll Mech Engn, Hengyang, Peoples R China.
通讯机构：
[Lin, WY ] U;Univ South China, Coll Mech Engn, Hengyang, Peoples R China.
摘要：
Mining wastewater with heavy metals poses a serious threat to the ecological environment. However, the acute single and combined ecological effects of heavy metals, such as chromium (Cr) and nickel (Ni), on freshwater ostracods, and the development of relevant prediction models, remain poorly understood. In this study, Heterocypris sp. was chosen to investigate the single and combined acute toxicity of Cr and Ni. Then, the quantitative structure-activity relationship (QSAR) model was used to predict the combined toxicity of Cr and Ni. The single acute toxicity experiments revealed high toxicity for both Cr and Ni. In addition, Cr exhibited greater toxicity compared to Ni, as evidenced by its lower 96-hour half-lethal concentration (LC50) of 1.07 mg/L compared to 4.7 mg/L for Ni. Furthermore, the combined acute toxicity experiments showed that the toxicity of Cr-Ni was higher than Ni but lower than Cr. Compared with the concentration addition (CA) and independent action (IA) models, the predicted results of the QSAR model were more consistent with the experimental results for the Cr-Ni combined acute toxicity. So, the high accuracy of QSAR model identified its feasibility to predict the toxicity of heavy metal pollutants in mining wastewater.
作者机构：
[Gao, Beibei; Cai, Tao; Tan, Jing; Zhang, Qingyan; Zeng, Qingyi] Univ South China, Sch Resources & Environm & Safety Engn, Hengyang 421001, Hunan, Peoples R China.;[Liu, Yi-Lin] Univ South China, Coll Mech Engn, Hengyang 421001, Hunan, Peoples R China.;[Chang, Sheng] Nanjing Univ Aeronaut & Astronaut, Sch Energy & Power Engn, Nanjing 210016, Jiangsu, Peoples R China.;[Zhao, Shuaifei] Deakin Univ, Inst Frontier Mat IFM, Geelong, Vic 3216, Australia.;[Wu, Suqing] Wenzhou Univ, Coll Life & Environm Sci, Natl & Local Joint Engn Res Ctr Ecol Treatment Tec, Key Lab Zhejiang Prov Water Environm & Marine Biol, Wenzhou 325000, Peoples R China.
通讯机构：
[Qingyi Zeng] S;[Yi-Lin Liu] C;College of Mechanical Engineering, University of South China, Hengyang, Hunan, 421001, China<&wdkj&>School of Resources & Environment and Safety Engineering, University of South China, Hengyang, Hunan, 421001, China
摘要：
A cobalt (Co)-doped perovskite molybdenum trioxide (alpha-MoO3) catalyst (Co-MO) was synthesized by a facile pyrolysis strategy and used for degrading various organic contaminants via peroxymonosulfate (PMS) activation. The doped Co was inserted in the inter space between the octahedron [MoO6], facilitating the growth of the alpha-MoO3 crystal on the [010] direction. This unique structure accelerated the activation of PMS as the Co-MO could function as a carrier for electron transfer to facilitate the Co(II)/Co(III) cycle in the Co-MO/PMS sys-tem. As a result, the Co-MO/PMS system showed noticeable activity for removing 100% bisphenol A (BPA) under a broad conditions within 30 min. The radical quenching test and electron paramagnetic resonance analysis revealed that singlet oxygen (1O2) was the main active species for BPA degradation in the Co-MO/PMS system, while free radicals, such as O2 center dot-, SO4 center dot-and center dot OH, were also produced as the intermediate species. Furthermore, the carrier mechanism may enable the Co-MO/PMS system maintain relatively high performance during repeat use, and also excellent adaptability was revealed by the well function in various water matrices and high activity in degrading various refractory organic pollutants. Our findings pave a useful avenue for the rational design of novel cobalt-doped catalysts with high catalytic performance toward wide environmental applications.
作者机构：
[Hou, Wei; Wang, Hongqiang; Wang, Qingliang; Li, Hui; Zhang, Rui; Hu, Eming; Lei, Zhiwu] Univ South China, Sch Resource & Environm & Safety Engn, Hengyang 421001, Peoples R China.;[Hou, Wei; Wang, Qingliang] Univ South China, Cooperat Innovat Ctr Nucl Fuel Cycle Technol & Eq, Hengyang 421001, Peoples R China.;[Wang, Hongqiang] Univ South China, Hengyang Key Lab Soil Pollut Control & Remediat, Hengyang 421001, Peoples R China.;[Wang, Qingliang; Hu, Eming; Lei, Zhiwu] Univ South China, Hunan Key Lab Rare Met Minerals Exploitat & Geol, Hengyang 421001, Peoples R China.
通讯机构：
[Qingliang Wang] S;School of Resource & Environment and Safety Engineering, University of South China, Hengyang, 421001, China<&wdkj&>Cooperative Innovation Center for Nuclear Fuel Cycle Technology and Equipment, University of South China, Hengyang, 421001, China<&wdkj&>Hunan Key Laboratory of Rare Metal Minerals Exploitation and Geological Disposal of Wastes, University of South China, Hengyang, 421001, China
作者机构：
[王玥; 代正燕; 李润; Zeng, Guo; 刘丹] Department of Nutrition, Food Safety and Toxicology, West China School of Public Health, Sichuan University, Chengdu 610041, China;[周容] West China Second Hospital, Shichuan University;[刘婧] Chengdu Women's and Children's Central Hospital;[张琚] Sichuan Provincial Maternal and Child Health Hospital;[Zeng, Guo] Email: zgmu2007@126. com
