作者机构：
School of Chemistry and Chemical Engineering, University of South China, Hengyang 421001, China;[林永成; 佘志刚] School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou 510275, China;School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China;[谭倪] School of Chemistry and Chemical Engineering, University of South China, Hengyang 421001, China, School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou 510275, China;[邵长伦] School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou 510275, China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China
通讯机构：
[Tan, N.] S;School of Chemistry and Chemical Engineering, University of South China, China
期刊：
Chemistry of Natural Compounds,2008年44(3):296-300 ISSN：0009-3130
通讯作者：
Tan, Ni
作者机构：
[Pan, Jiahui; Tan, Ni; Tao, Yiwen; Wang, Sanyong; Xu, Fang; Lin, Yongcheng; She, Zhigang] Sun Yat Sen Zhongshan Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China.;[Tan, Ni] Univ S China, Sch Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.;[Jones, E. B. Gareth] City Univ Hong Kong, Dept Biol & Chem, Hong Kong 999077, Hong Kong, Peoples R China.
通讯机构：
[Tan, Ni] S;Sun Yat Sen Zhongshan Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China.
摘要：
A new alternariol derivative, 2240B (1), together with alternariol (2), alternariol 4,10-dimethyl ether (3), and alternariol 4-methyl ether (4), was isolated from the ethyl acetate extract of the liquid medium GYT of No. 2240, the mangrove endophytic fungus from the South China Sea Coast. The structure of compound 1 was unambiguously elucidated as alternariol 4-methyl-10-acethyl ester by spectra including one/two-dimensional NMR, HREIMS, IR, and UV. The structures of compounds 2-4 were also established by spectroscopic analyses and comparison with related literature data. The anticancer tests showed that compounds 2 and 4 had strong activities against KB and KBv200 cells with IC50 values of 3.17, 3.12, and 4.82, 4.94 mu g/mL, while compounds 1 and 3 exhibited weak activities against the two kinds of tumor lines with IC50 values of more than 50 mu g/mL.
作者：
Tan Ni*;Pan Jia-Hui;Wang San-Yong;Xu Fang;Tao Yi-Wen;...
期刊：
中国化学,2008年26(4):741-744 ISSN：1001-604X
通讯作者：
Tan Ni
作者机构：
[Pan Jia-Hui; Wang San-Yong; She Zhi-Gang; Xu Fang; Lin Yong-Cheng; Tan Ni; Tao Yi-Wen] Sun Yat Sen Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China.;[Tan Ni] Univ S China, Sch Chem & Chem Engn, Henyang 421001, Hunan, Peoples R China.
通讯机构：
[Tan Ni] S;Sun Yat Sen Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China.
作者机构：
[谭倪] School of Chemistry and Chemical Engineering, University of South China, Hengyang 421001, China;[邵长伦] School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China;[谭倪; 邵长伦; 潘嘉慧; 林永成; 何丽仙; 佘志刚] School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou 510275, China
通讯机构：
School of Chemistry and Chemical Engineering, University of South China, China
