摘要：
A resonance light scattering (RLS) method for the direct detection of uranium (VI) or uranyl in aqueous solution without separation procedure has been reported in this paper. Sulfo-salophen, a water-soluble tetradentate Schiff base ligand of uranyl, reacted with uranyl to form a complex. The complex reacted further with oxalate to form supramolecular dimer with large molecular volume, resulting in a production of strong RLS signal. The amount of uranium (VI) was detected through measuring the RLS intensity. A linear range was found to be 0.2–30.0 ng/mL under optimal conditions with a detection limit of 0.15 ng/mL. The method has been applied to determine uranium (VI) in environmental water samples with the relative standard deviations of less than 5 % and the recoveries of 98.8–105.8 %. The present technique is suitable for the assay of uranium (VI) in environmental water samples collected from different sources.
摘要：
To reveal the structure-function relationship of heme proteins, and to provide clues for creating artificial heme proteins with improved functions, we here use myoglobin (Mb) as a model protein, and report that its peroxidase activity can be enhanced by construction of two distal histidines and a channel to the heme pocket. It showed that in addition to a single distal histidine with a suitable distance to the heme iron (Phe43 to His43 mutation), a second distal histidine (Leu29 to His29 mutation) can work cooperatively to increase the turnover number, mimicking the role of well-known His-Arg pair in native peroxidases. Moreover, a channel created to the heme pocket by removal of the native His64 gate (His64 to A1a64 mutation) was shown to facilitate the binding of substrate, resulting in enhanced catalytic efficiency for the triple mutant L29H/F43H/H64A Mb, which is beyond the addition of both double mutants, L29H/H64A Mb and F43 H/H64A Mb. These results provide valuable information for elucidating the structure-function relationship of heme proteins. In addition, this study provides clues for design of artificial heme proteins, and the strategy of creating a channel to the heme active center is expected be extended to design of other artificial enzymes with improved catalytic performance. (C) 2016 Elsevier B.V. All rights reserved.
摘要：
Type 2 diabetes is a major risk factor of the development of atherosclerosis in humans. However, studies examining mechanisms underlying diabetes-accelerated atherosclerosis have been limited by the lack of suitable humanoid animal models. Pigs have a cardiovascular system that is very similar to that of humans and is useful as a model for human physiology and pathophysiology. In this study, we established a new miniature pig model for studying dyslipidaemia and atherosclerosis in diabetes. Chinese Guizhou minipigs were fed a normal control diet or a high-fat/high-sucrose diet (HFSD) for 6 months. Plasma total cholesterol (TC), high-density lipoprotein cholesterol, triglyceride (TG), insulin and glucose were quantified at monthly intervals. The induction of insulin resistance and dysfunction of the pancreatic β-cell were assessed by oral glucose tolerance test and insulin sensitivity test. The aortic fatty streak lesions were quantified following lipid staining with Sudan IV. During the feeding period, mild high plasma TC and TG were induced. At the end of 6 months, in HFSD-fed animals, the adipocytes were hypertrophic, fat deposit in the liver was observed, loss of pancreatic β-cells was observed, and the aortic fatty streak lesions were clearly present in the animals' aortas. Our study established that miniature pigs that were fed a HFSD without adding dietary cholesterol developed insulin resistance, mild diabetes and atherosclerotic lesions. HFSD-fed miniature pigs may be good animal models for research on the treatment of diabetic dyslipidaemia complicated with atherosclerosis.
摘要：
A novel Zn²⁺ fluorescent probe Nʹ-((4′-(diphenylamino)-4-hydroxy-[1,1′-biphenyl]-3-yl)methylene)-2-hydroxybenzohydrazide (TPA-HPH) with a larger Stokes shift (210 nm) was designed and synthesized, which was seen to be highly selective and sensitive to Zn²⁺ ion over other metal ions in the system of MeCN:H2O (V/V = 6:4, pH = 7.0). Meanwhile, it was observed that the TPA-HPH solution changed from colorless to yellow by “naked eye” when Zn²⁺ was added. Under optimized conditions, the fluorescence intensity of the probe showed a good linear relationship with Zn²⁺ ion concentration in the range of 0–10 μM with a low detection limit of 7.3 × 10⁻¹⁰ M. The fluorescent mechanism was proposed. Most importantly, TPA-HPH could realize on-site monitor and live cell imaging for Zn²⁺ ion. Graphic abstract Open image in new window
期刊：
2017 3RD INTERNATIONAL CONFERENCE ON ENVIRONMENTAL SCIENCE AND MATERIAL APPLICATION (ESMA2017), VOLS 1-4,2018年108 ISSN：1755-1307
通讯作者：
Liu, Yong
作者机构：
[Zhao, Guodong; Zhang, Yan; Yang, Zhu; Liu, Yong; Lou, Yalong] Univ South China, Sch Environm Protect & Safety Engn, Hengyang 421001, Hunan, Peoples R China.;[Zhao, Guodong; Zhang, Yan; Yang, Zhu; Liu, Yong; Peng, Guowen; Lou, Yalong] Hu Nan Prov Engn Technol Res Ctr UraniumTailings, Hengyang 421001, Hunan, Peoples R China.;[Peng, Guowen] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.
通讯机构：
[Liu, Yong] Univ South China, Sch Environm Protect & Safety Engn, Hengyang 421001, Hunan, Peoples R China.;[Liu, Yong] Hu Nan Prov Engn Technol Res Ctr UraniumTailings, Hengyang 421001, Hunan, Peoples R China.
会议名称：
3rd International Conference on Environmental Science and Material Application (ESMA)
会议时间：
NOV 25-26, 2017
会议地点：
Chongqing, PEOPLES R CHINA
会议主办单位：
[Lou, Yalong;Liu, Yong;Zhao, Guodong;Zhang, Yan;Yang, Zhu] Univ South China, Sch Environm Protect & Safety Engn, Hengyang 421001, Hunan, Peoples R China.^[Lou, Yalong;Liu, Yong;Peng, Guowen;Zhao, Guodong;Zhang, Yan;Yang, Zhu] Hu Nan Prov Engn Technol Res Ctr UraniumTailings, Hengyang 421001, Hunan, Peoples R China.^[Peng, Guowen] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.
会议论文集名称：
IOP Conference Series-Earth and Environmental Science
摘要：
A year-long monitoring of gamma radiation effective dose rate and radon concentration had been done in the reservoir area of one uranium tailings pond in Hunan province (The monitoring area included indoor and outdoor area of residential buildings and workshops, tailings dam slope). Afterwards, the annual effective radiation dose of the people in that radiation environment had been calculated based on the results of monitoring, as well as a radiation risk assessment. According to the assessment, gamma radiation effective dose rate and radon concentration in the monitoring area were low, and the annual effective radiation dose was far below the international standard (30mSv), which showed that the radiation would not put the people's health at risk. However, the annual effective radiation dose of gamma was far above that of radon in the area of uranium tailings pond; therefore, it's advisable to take quarantine measures in in the area of uranium tailings pond to keep the surrounding residents away from unnecessary ionizing radiation.
作者机构：
[Yang, Pengfei] Xiangtan Univ, Sch Chem Engn, Key Lab Green Catalysis & Chem React Engn Hunan P, Xiangtan 411105, Hunan, Peoples R China.;[Wang, Zhe; Yang, Pengfei; Zhou, Jicheng] Univ South China, Sch Chem Engn, Hunan 421001, Peoples R China.
会议名称：
International Conference of Environment Materials and Environment Management
会议时间：
JUL 24-25, 2010
会议地点：
Harbin, PEOPLES R CHINA
会议主办单位：
[Yang, Pengfei] Xiangtan Univ, Sch Chem Engn, Key Lab Green Catalysis & Chem React Engn Hunan P, Xiangtan 411105, Hunan, Peoples R China.^[Yang, Pengfei;Zhou, Jicheng;Wang, Zhe] Univ South China, Sch Chem Engn, Hunan 421001, Peoples R China.
会议论文集名称：
Advanced Materials Research
关键词：
NO decomposition;Cu/ZSM-5 containing Ce and Zr;Active site;Oxygen forbearance
摘要：
The Zr-Cu-Ce/ZSM-5 catalysts prepared by the simultaneous ion-exchange showed high activity for NO decomposition in the presence of O-2, the highest conversion of NO was up to 75%, indicating that the Ce and Zr addition can enhance the activity of catalysts. A new highly active site, which facilitates oxygen mobilization and desorption, could be formed in the sample due to the Ce and Zr addition. In addition, the Zr addition can significantly improve the thermal stability of the catalyst.
作者机构：
[Wang, M.] Univ South China, Sch Nucl Sci & Technol, Hengyang 421001, Hunan, Peoples R China.;[Shan, D. C.; Liao, Y.] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.
会议名称：
6th Global Conference on Materials Science and Engineering (CMSE)
会议时间：
OCT 24-27, 2017
会议地点：
Beijing, PEOPLES R CHINA
会议主办单位：
[Wang, M.] Univ South China, Sch Nucl Sci & Technol, Hengyang 421001, Hunan, Peoples R China.^[Shan, D. C.;Liao, Y.] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.
会议论文集名称：
IOP Conference Series-Materials Science and Engineering
摘要：
In this paper, several mechanical responses of thermoplastic polyurethane (TPU) filled with nano-scale attapulgite (AT) particles, including cyclic loading-unloading behavior, dynamic mechanical behavior and stress relaxation have been investigated. With the addition of AT, it is noticed that the strength, modulus and stress relaxation time of TPU increased significantly compared to that of unfilled materials. It is also observed that, whether filled or unfilled TPU, pronounced inelastic mechanical features such as Mullins effect, residual strain and hysteresis, occurred mainly during the first load loop, but became more notable with AT increase.
摘要：
Recently, the computer simulation of molecular imprinted polymer (MIP) has been suggested as a rational method to search for optimal imprinting conditions in environmental science and engineering. In this paper, the sulfisoxazole conformation was optimized and sulfisoxazole and the functional monomers were computed using quantum chemistry method at MP2 level with 6-31++ G* basis set. The binding energy, Delta E, an important parameter for their interactions, was used to select the best functional monomers, and the solvation energy was used to choose the most suitable solvent. The results indicated that the best functional monomer was acrylic acid, the most suitable solvent was carbon tetrachloride, and the most stable molecular model was the hydrogen bond formed between the H18 in sulfisoxazole and the O2 in acrylic acid with 1: 1 molar ratio of SIZ to AA. These results had an insight into the interaction of the sulfisoxazole MIP, which provided theoretical reference for SIZ-MIP.
期刊：
2019 3RD INTERNATIONAL WORKSHOP ON RENEWABLE ENERGY AND DEVELOPMENT (IWRED 2019) IOP Conference Series-Earth and Environmental Science,2019年267(3) ISSN：1755-1307
通讯作者：
Deng, CG
作者机构：
[Deng Changai; Peng Chao; Yang Shaohua] Univ South China, Coll Chem & Chem Engn, Hengyang 421001, Peoples R China.
通讯机构：
[Deng, CG ] Univ South China, Coll Chem & Chem Engn, Hengyang 421001, Peoples R China.;Univ South China, Coll Chem & Chem Engn, Hengyang 421001, Peoples R China.
会议名称：
14th International Conference on Electronic Materials and Packaging (EMAP)
会议时间：
DEC 13-16, 2012
会议地点：
Hong Kong, PEOPLES R CHINA
会议主办单位：
[Zhang, Enhe;Zhao, Yubao] Univ South China, Sch Chem & Chem Engn, 1068 Xueyuan Ave, Hengyang 421000, Peoples R China.^[Zhang, Enhe;Luo, Suibin;Yang, Wenhu;Yu, Shuhui;Sun, Rong] Chinese Acad Sci, Shenzhen Inst Adv Technol, Shenzhen 518055, Peoples R China.
会议论文集名称：
International Conference on Electronic Materials and Packaging
摘要：
In this work, a simple two-step route has been developed to synthesize ultrafine barium titanate (BaTiO3) with size ranging from 30 nm to 100nm by reacting barium hydroxide with tetrabutyl titanate in mixing solvent. This method facilitates the process-control and the property tailoring of the particles. The effect of 1,4-butylene glycol on hydrolysis rate of tetrabutyl titanate, temperature, solvent ratio between isopropanol and water, the particle size, the crystalline phase have been investigated. The prepared BaTiO3 nanoparticles were characterized using X-ray diffraction and scanning electron microscopy (SEM). The results show that the particle size can be easily tuned by adjusting the ratio of 1, 4-butylene glycol, isopropanol and water in solution. The dielectric behavior of the BaTiO3 /PVDF at low frequency show that the interfacial polarization acts as an important role for the high dielectric constant (epsilon(r)).
摘要：
A new potentiometric titration method coupled with multivariate calibration using a flow injection technique for the simultaneous determination of multi-components in alloy has been developed, the titrant is a mixture of EDTA and sodium fluoride, both mercury film electrode and fluorinion selective electrode are inserted in the flow cell. In a process of titration, both the potentiometric of mercury ion and the mixed proportion of reactants at each titration point can be obtained simultaneously from the two electrodes, and then the concentration of each component in the mixture can be obtained from the titration curves by multivariate calibration method. The method is free of volumetric and time measurements, and reduces the consumption of reagents and samples. The method is also very quick in analysis rapidity. The method has been applied for the simultaneous determination of copper, lead and zinc in alloy samples with the relative standard deviation of 0.18%similar to 0.45% and the recovery of 99.5%similar to 101.6%.
作者机构：
[Wang, Zheng-Hao; Luo, Cai-Wu; Lei, Bo] Univ South China, Sch Environm & Safety Engn, Hengyang 421001, Hunan, Peoples R China.;[Li, An] Hunan Inst Sci & Technol, Coll Chem & Chem Engn, Yueyang 414006, Hunan, Peoples R China.;[Liang, Shan] Univ South China, Sch Chem & Chem Engn, Hengyang, Hunan 421001, Peoples R China.;[Chao, Zi-Sheng] Changsha Univ Sci & Technol, Coll Mat Sci & Engn, Changsha 410114, Hunan, Peoples R China.
通讯机构：
[Luo, Cai-Wu] Univ South China, Sch Environm & Safety Engn, Hengyang 421001, Hunan, Peoples R China.
会议名称：
3rd International Conference on Mechanics, Materials and Structural Engineering (ICMMSE)
会议时间：
APR 20-22, 2018
会议地点：
Okinawa, JAPAN
会议主办单位：
[Luo, Cai-Wu;Lei, Bo;Wang, Zheng-Hao] Univ South China, Sch Environm & Safety Engn, Hengyang 421001, Hunan, Peoples R China.^[Li, An] Hunan Inst Sci & Technol, Coll Chem & Chem Engn, Yueyang 414006, Hunan, Peoples R China.^[Liang, Shan] Univ South China, Sch Chem & Chem Engn, Hengyang, Hunan 421001, Peoples R China.^[Chao, Zi-Sheng] Changsha Univ Sci & Technol, Coll Mat Sci & Engn, Changsha 410114, Hunan, Peoples R China.
会议论文集名称：
AIP Conference Proceedings
摘要：
In this work, series of catalysts like bimetallic oxides and supported ZSM-5 (acid and/or metal), were applied for the synthesis of pyridine and 3-picoline from acrolein diethyl acetal, water and ammonia in a fixed-bed reactor. The results showed that bimetallic oxides and alkaline catalysts exhibited extremely low catalytic activities whereas HZSM-5 had significantly better than MCM-41 and SBA-15. Among kinds of catalysts, the total yield of pyridine and 3-picoline over Mg-ZSM-5 through ion-exchanged process reached the highest.
作者机构：
[Deng, Chang'ai; Xiao, Xilin; Liao, Lifu; Zhou, Xin; Nie, Changming; He, Bo] Univ South China, Coll Chem & Chem Engn, Hengyang 421001, Peoples R China.
会议名称：
2015 International Conference on Materials,Environmental and Biological Engineering(MEBE 2015)
会议时间：
2015-03-28
会议地点：
中国广西桂林
关键词：
Staphylococcus aureus ssp anaerobius (S. aureus);Penicillin G;Targeted drug delivery;Bone;Ti-Al intermetallic compounds porous material
摘要：
Bacterial infection is one of the most common problems after orthopedic implant surgery. If not prevented, bacterial infection can result in serious and life threatening conditions such as osteomyelitis. Thus, in order to reduce chances of such serious complication, patients are often subjected to antibiotic drug therapy for 6-8 weeks after initial surgery. The antibiotics are systemically delivered either intravenously, intramuscularly or topically. Systemic antibiotic delivery entails certain drawbacks such as systemic toxicity and limited bioavailability. Further, in order for the drug to be effective at the site of implantation, high doses are required, which can result in undesired side effects in patients. Thus, local antibiotic therapy is the preferred way of administering drugs. To that end, we have developed Ti-Al intermetallic compounds porous material for local delivery of antibiotics off-implant at the site of implantation. The Ti-Al intermetallic compounds porous materials were fabricated with reactively synthesizing. The fabrication strategies allow us to precisely control the dimension of aperture, thus enabling us to load different amounts of drugs and control the release rates. In this work we have fabricated Ti-Al intermetallic compounds porous material with 40 similar to 200 nm and 2 similar to 5 mu m apertures. We have loaded these tubes with 180, 360 and 540 mu g of penicillin G. The penicillin G release kinetics from the apertures and its effect on Staphylococcus aureus ssp. anaerobius (S. aureus) adhesion were investigated. Further, an osteosarcoma cell line called MG-63 was cultured on penicillin G-loaded aperture to evaluate the effect of Ti-Al intermetallic compounds porous material on cell functionality. Our results indicate that we can effectively fill the apertures with the drug and the drug eluting apertures significantly reduced bacterial adhesion on the surface. Also, there is enhanced MG-63 differentiation on apertures filled with penicillin G.
作者机构：
[Cai, Guilong] Univ South China, Sch Chem & Chem, Hengyang 421001, Hunan, Peoples R China.
会议名称：
2nd International Conference on Chemical, Material and Metallurgical Engineering (ICCMME 2012)
会议时间：
DEC 15-16, 2012
会议地点：
Kunming, PEOPLES R CHINA
会议主办单位：
[Cai, Guilong] Univ South China, Sch Chem & Chem, Hengyang 421001, Hunan, Peoples R China.
会议论文集名称：
Advanced Materials Research
关键词：
surfactant;leaching of uranium;sandstone-type ores
摘要：
This paper researched the effect of six surfactant including aodium dodecyl benzene sulfonate(SDBS), cetyltrimethyl ammonium bromide(CTAB), polyoxyethylene octylphenol ether (OP-10), Triton X-100(TX-100), FSO and their mixture on surface tension of the leaching solution and on leaching rate of uranium in sandstone uranium ores. Results showed that all kinds of surfactant could observably reduce the surface tension of the leaching solution at low concentration. The surface tension of leaching solution containing 1g/L FSO and 0.01g/L mixture surfactant(mOP-10 /mFSO; 7:3) was 20.7mN/m and 17.9 mN/m respectively. Results of agitation leach experiments showed that FSO and the system of OP-10 and FSO could improve the leaching rate, and the leaching rate of uranium could be increased by 14.16% and 16.08% to 92.54% and 94.09% respectively. These results indicated that the way of reducing the surface tension of the leaching solution could improve the leaching rate of uranium.
