[Deng, Chang'ai; Xiao, Xilin; Liao, Lifu; Zhou, Xin; Nie, Changming; He, Bo] Univ South China, Coll Chem & Chem Engn, Hengyang 421001, Peoples R China.
通讯机构:
[Xiao, Xilin] U
Univ South China, Coll Chem & Chem Engn, Hengyang 421001, Peoples R China.
语种:
英文
关键词:
Staphylococcus aureus ssp. anaerobius (S. aureus);Penicillin G;Targeted drug delivery;Bone;Ti-Al intermetallic compounds porous material
期刊:
PROCEEDINGS OF THE 2015 INTERNATIONAL CONFERENCE ON MATERIALS, ENVIRONMENTAL AND BIOLOGICAL ENGINEERING
ISSN:
2352-5401
年:
2015
卷:
10
页码:
317-320
会议名称:
International Conference on Materials, Environmental and Biological Engineering
会议论文集名称:
International Conference on Materials, Environmental and Biological Engineering, Part 1: Guilin(CN).28-30 March 2015
会议时间:
2015-03-28
会议地点:
Guilin
会议主办单位:
[Xiao, Xilin;Liao, Lifu;Nie, Changming;Zhou, Xin;He, Bo;Deng, Chang'ai] Univ South China, Coll Chem & Chem Engn, Hengyang 421001, Peoples R China.
主编:
Zhang, G Lee, M
出版地:
29 AVENUE LAVMIERE, PARIS, 75019, FRANCE
出版者:
ATLANTIS PRESS
ISBN:
978-94-62520-57-8
基金类别:
financial support from the National Natural Science Foundation of China under the grant 31200140
机构署名:
本校为第一且通讯机构
院系归属:
化学化工学院
摘要:
Bacterial infection is one of the most common problems after orthopedic implant surgery. If not prevented, bacterial infection can result in serious and life threatening conditions such as osteomyelitis. Thus, in order to reduce chances of such serious complication, patients are often subjected to antibiotic drug therapy for 6-8 weeks after initial surgery. The antibiotics are systemically delivered either intravenously, intramuscularly or topically. Systemic antibiotic delivery entails certain drawbacks such as systemic toxicity and limited bioavailability. Further, in order for the drug to b...