摘要:
In this study, the potential applications of perfect boron carbide (BC3) nanosheet and single-vacancy defect BC3 nanosheets (SVBC3-B and SVBC3-C), as the drug delivery vehicle for 6-mercaptopurine (6-MP), are investigated based on the calculation of the density functional theory (DFT). The interactions of the 6-MP drug with the BC3 nanosheet, SVBC3-B and SVBC3-C are simulated in the gas phase, water solvent and acidic solvent, respectively. The results demonstrated that the 6-MP drug tends to adsorb parallel on the surface of the BC3 nanosheet, and the adsorption energy on SVBC3-B is the largest, followed by the perfect BC3. The interactions between the 6-MP drug and the perfect BC3 nanosheet, SVBC3-B and SVBC3-C will be weakened in a water solvent. Furthermore, the interaction force between the 6-MP drug and the perfect BC3 nanosheet or SVBC3-B nanosheet in an acidic solvent is more significant than that in a water solvent, which is not conducive to separating the 6-MP drug from the two kinds of BC3 nanosheets. But, the adsorption energy of the 6-MP drug on SVBC3-C in the acidic solvent is much lesser than that in the water solvent, which indicates that the 6-MP drug can be easily separated from SVBC3-C in the acidic environment. The PH value of cancer tissue is just acidic, which provides an ideal environment for separating 6-MP. Generally, the results confirmed the possibility of SVBC3-C as a delivery vehicle for the 6-MP drug.
作者机构:
[Zhou, Nan] School of Nuclear Science and Technology, University of South China, Hengyang, People’s Republic of China;[Qin, Yong; Tan, Jie; Cheng, Jinjuan; Wu, Xijun] School of Mathematics and Physics, University of South China, Hengyang, People’s Republic of China;[He, Shuaixing; Li, Hai] Hangzhou Xiangting Technology Co., Ltd, Hangzhou, People’s Republic of China
通讯机构:
[Xijun Wu] S;School of Mathematics and Physics, University of South China, Hengyang, People’s Republic of China
作者:
Zheng, Lijing;Kan, Haibin;Li, Yanjun;Peng, Jie;Tang, Deng
期刊:
IEEE Transactions on Information Theory,2022年68(11):7528-7537 ISSN:0018-9448
通讯作者:
Kan, H.
作者机构:
[Zheng, Lijing] Univ South China, Sch Math & Phys, Hengyang 421001, Hunan, Peoples R China.;[Kan, Haibin] Fudan Univ, Shanghai Key Lab Intelligent Informat Proc, Sch Comp Sci, Shanghai 200433, Peoples R China.;[Kan, Haibin] Fudan Univ, Shanghai Engn Ctr Blockchains, Shanghai 200433, Peoples R China.;[Li, Yanjun] Anhui Univ Finance & Econ, Inst Stat & Appl Math, Bengbu 233030, Anhui, Peoples R China.;[Peng, Jie; Li, Yanjun] Shanghai Normal Univ, Math & Sci Coll, Shanghai 200234, Peoples R China.
通讯机构:
[Kan, H.] F;Fudan University, Shanghai Key Laboratory of Intelligent Information Processing, School of Computer Sciences, The Shanghai Engineering Center of Blockchains, Shanghai, China
摘要:
Existence, uniqueness and stability of forced pulsating waves as well as gap formation of reaction dif-fusion models in a shifting habitat are challenging problems in the field of propagation dynamics. In this paper, we design to tackle these problems for a time periodic Lotka-Volterra competition system. By using alternatively-coupling upper-lower solution method, we establish the existence of forced pulsating traveling wave, as long as the shifting speed falls in a finite interval where the end points are obtained from KPP-Fisher speeds. The asymptotic behaviors of the forced pulsating traveling wave are derived and this helps us show that this wave is unique. Moreover in the Lyapunov sense, the stability of the forced pulsating wave is also studied. Finally, when the forced speed is beyond the finite interval, gap formation is investigated theoretically and illustrated further by numerical simulations. (c) 2022 Elsevier Inc. All rights reserved.
摘要:
In this paper, we investigate the innermost stable circular orbit (ISCO) of spinning particles around a rotating black hole surrounded by the perfect fluid dark matter (PFDM). The motion of spinning particles is derived by Mathisson–Papapetrou–Dixon equation and the ISCO parameters are obtained by the radial effective potential. The effect of PFDM density parameter on the motion of spinning particles is analyzed. The results show that the effect of PFDM is nonlinear, and the radius of ISCO varies nonmonotonically with PFDM density parameter.
作者机构:
[谭清懿; 杨开建; 乔冠瑾] Department of Electrical Engineering, University of South China, Hengyang, 421001, China;[杜丹] Department of Mathematics and Physics, University of South China, Hengyang, 421001, China;[潘光祖; 周华; 龚学余] Department of Nuclear Science and Technology, University of South China, Hengyang, 421001, China
通讯机构:
[Du, D.] D;Department of Mathematics and Physics, China
摘要:
Many studies have shown that microbubble cavitation is one mechanism for vascular injury under ultrasonic excitation. Previous work has attributed vascular damage to vessel expansions and invaginations due to the expansion and contraction of microbubbles. However, the mechanisms of vascular damage are not fully understood. In this paper, we investigate, theoretically and experimentally, the vessel injury due to stress induced by ultrasound-induced cavitation (UIC). A bubble-fluid-vessel coupling model is constructed to investigate the interactions of the coupling system. The dynamics process of vessel damage due to UIC is theoretically simulated with a finite element method, and a focused ultrasound (FU) setup is carried out and used to assess the vessel damage. The results show that shear stress contributes to vessel injury by cell detachment while normal stress mainly causes distention injury. Similar changes in cell detachment in a vessel over time can be observed with the experimental setup. The severity of vascular injury is correlated to acoustic parameters, bubble-wall distance, and microbubble sizes, and the duration of insonation..
期刊:
Journal of Radiation Research and Applied Sciences,2022年15(3):83-90 ISSN:1687-8507
通讯作者:
Yong Liu<&wdkj&>Zhenghua Xu
作者机构:
[Chen, Yifan; Dai, Xingwang] Univ South China, Sch Resources Environm & Safety Engn, Hengyang 421001, Hunan, Peoples R China.;[Chen, Yifan; Dai, Xingwang; Xu, Zhenghua; Liu, Yong] Hunan Prov Engn Technol Res Ctr Uranium Tailings, Hengyang 421001, Peoples R China.;[Huang, Danxia; Hong, Yang] Univ South China, Sch Econ Management & Law, Hengyang 421001, Hunan, Peoples R China.;[Zhang, Min] China Nucl Huachen Construct Engn Co LTD, Xian 710000, Shaanxi, Peoples R China.;[Xu, Zhenghua] Univ South China, Sch Math & Phys, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Yong Liu; Zhenghua Xu] H;Hunan Province Engineering Technology Research Center of Uranium Tailings Treatment, Hengyang, 421001, China<&wdkj&>Hunan Province Engineering Technology Research Center of Uranium Tailings Treatment, Hengyang, 421001, China<&wdkj&>School of Mathematics and Physics, University of South China, Hengyang, 421001, Hunan, China
关键词:
Uranium tailings pond;Interpreted structural model (ISM);Resilience;Risk coupling;Emergency management
摘要:
The safety of uranium tailings pond is closely related to social stability and economic development, so it is necessary to improve the emergency management of uranium tailings pond to ensure its safety by adjusting the emergency plan. The Interpretive Structural Model (ISM) is used to analyze the structural relationship between the main risk factors leading to the occurrence of emergencies. The results show that attention should be paid to the risk factors originating from humans and infrastructures, and effective management measures should be adopted in the process of emergency management, for example, people build tighter employee access system, clarify the responsibilities of employees at all levels, and improve monitoring and organizational means. Ac-cording to the results of ISM analysis, a structural risk control system can be constructed, and a defensive barrier that can effectively block the risk coupling transmission can be designed to prevent the risk from being trans-formed into an event. For other risks, system resilience management should be strengthened to respond to risks. The process is set as emergency response and accident response. Different management objects use different management methods to make emergency management work efficiently.
作者机构:
[Zhou, Yajun; Gao, You] Univ South China, Sch Math & Phys, Hengyang 421001, Peoples R China.;[Zhou, Yajun] Hunan Vocat Coll Nationalities, Sch Primary Educ, Yueyang 414000, Peoples R China.
通讯机构:
[You Gao] S;School of Mathematics and Physics, University of South China, Hengyang 421001, China<&wdkj&>Author to whom correspondence should be addressed.
关键词:
Lyapunov method;time-delay;genetic regulatory networks;discontinuous switch control strategy;fixed-time synchronization;settling time
摘要:
The synchronous genetic regulatory networks model includes the drive system and response system, and the drive-response system is symmetric. From a biological point of view, this model illustrates the dynamic behaviors in gene-to-protein processes, in terms of transcription and translation. This paper introduces a model of genetic regulatory networks with time delay. The fixed-time synchronization control problem of the proposed model is studied based on fixed-time stability theory and the Lyapunov method. Concretely, the authors first propose a way to switch from the given model to matrix form. Then, two types of novel controllers are designed and the corresponding sufficient conditions are investigated respectively to ensure the fixed-time synchronization goal. Moreover, the settling times of fixed-time synchronization are estimated for the addressed discontinuous controllers, which are not dependent on the initial or delayed states of the model. Finally, numerical simulations are presented and compared to illustrate the benefits of the theoretical results.
期刊:
Journal of Vibration Engineering & Technologies,2022年10(4):1291-1308 ISSN:2523-3920
通讯作者:
Li, ZB
作者机构:
[Li, Zhenbo; Li, ZB] Univ South China, Sch Math & Phys, Hengyang 421001, Peoples R China.;[Tang, Jiashi] Hunan Univ, Coll Mech & Vehicle Engn, Changsha 410082, Hunan, Peoples R China.
通讯机构:
[Li, ZB ] U;Univ South China, Sch Math & Phys, Hengyang 421001, Peoples R China.
关键词:
Generalized Padé–Lindstedt–Poincaré Method;Homo-Heteroclinic Solutions;Entire \(\Phi^{6}\)-Van der Pol oscillator;Generalized Duffing-Harmonic-Van der Pol Oscillator
摘要:
In this work, the generalized Padé–Lindstedt–Poincaré method is applied to obtain high accurate homoclinic and heteroclinic solutions of the entire
$$\Phi^{6}$$
-Van der Pol oscillator with asymmetric potential and the generalized Duffing-Harmonic-Van der Pol oscillator. Meanwhile, the critical values of bifurcation parameter are also predicted To improve the efficiency and accuracy, several new types of generalized Padé approximant are constructed and introduced into the procedure of the present method. In this method, the perturbation equations obtained from the Lindstedt–Poincaré procedures are solved by generalized Padé approximation method instead of the traditional integration method. Consequently, the proposed method does not involve the cumbersome calculations of derivation and integration compared to traditional perturbation-based methods. It means that the high order perturbation solutions can be easily obtained via the present method. To demonstrate the feasibility of the method, the oscillators with small and big parameters are both solved. All solutions and critical values obtained in this paper are compared to the results obtained from the Runge–Kutta method. It shows high agreement between the present results and the numerical ones. In general, this method has characters of simple calculation, high accuracy and wide applicability, which can be regarded as a supplement and improvement of existing perturbation-based method.
作者机构:
[Li, Xiao-Hua; Pan, Xiao; Zou, You-Tian] Univ South China, Sch Nucl Sci & Technol, Hengyang 421001, Peoples R China.;[Li, Xiao-Hua; Wu, Xi-Jun] Univ South China, Cooperat Innovat Ctr Nucl Fuel Cycle Technol & Eq, Hengyang 421001, Peoples R China.;[Li, Xiao-Hua] Hunan Normal Univ, Key Lab Low Dimens Quantum Struct & Quantum Contr, Changsha 410081, Peoples R China.;[Wu, Xi-Jun] Univ South China, Sch Math & Phys, Hengyang 421001, Peoples R China.;[He, Biao] Cent South Univ, Coll Phys & Elect, Changsha 410083, Peoples R China.
通讯机构:
[Xiao-Hua Li] S;School of Nuclear Science and Technology, University of South China, Hengyang 421001, China<&wdkj&>Cooperative Innovation Center for Nuclear Fuel Cycle Technology & Equipment, University of South China, Hengyang 421001, China<&wdkj&>Key Laboratory of Low Dimensional Quantum Structures and Quantum Control, Hunan Normal University, Changsha 410081, China
关键词:
favored one proton radioactivity;one-parameter model;half-lives
摘要:
Based on our direct shear creep experiment and the direct shear rheological constitutive model, a semi-empirical time-dependent parameter of the shear strength is obtained by Mohr-Coulomb shear strength theory, and different time-dependent traction force calculations between deep-sea sediment and a tracked miner are conducted by the work-energy principle. The time-dependent traction force calculation under its influencing factors, including the time, track shoe number, and grounding pressure, are analyzed and proved to be valid by the traction force experiment of a single-track shoe. The results show that the time-dependent cohesion force obtained by a semi-empirical way can be easily used to deduce the time-dependent traction force models under the different grounding pressure distributions and applied into deep-sea engineering application conveniently; the verified traction force models by the traction force experiment of a single-track shoe illustrate that traction force under the decrement grounding pressure distribution is the worst among the four kinds of grounding pressure distributions and suggested for evaluating the most unfavorable traction force and calculating the trafficability and stability of the deep-sea tracked miner.