作者机构：
[Tao, Yu-Qiang; Wang, Bing-Xin; He, Min-Jie] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.;[Tao, Yu-Qiang] Hunan Key Lab Design & Applicat Actinide Complexe, Hengyang 421001, Peoples R China.;[Xiong, Hui-Wen; Li, Zhi-You] Cent South Univ, State Key Lab Powder Met, Changsha 410083, Peoples R China.
通讯机构：
[Yu-Qiang Tao] H;Hunan Key Laboratory for the Design and Application of Actinide Complexes, Hengyang 421001, China<&wdkj&>School of Chemistry and Chemical Engineering, University of South China, Hengyang 421001, China<&wdkj&>Author to whom correspondence should be addressed.
关键词：
metal matrix composites;erosion;anodic dissolution;inert anode;Al electrolysis
摘要：
Here, 20 Cu-20 Ni-54 NiFe2O4-6 NiO (wt%) cermets were prepared via the powder metallurgy process, and the electrolytic corrosion behavior of the cermets at 880 degrees C and 960 degrees C was studied through the microstructure analysis by SEM and EDS. Results show that the ceramic phase is seriously affected by chemical corrosion at 880 degrees C electrolysis, and it is difficult to form a dense ceramic surface layer. A dense ceramic surface layer is formed on the bottom of the anode electrolyzed at 960 degrees C, and the dense layer thickens with the extension of the electrolysis time. The formation of the dense surface layer is mainly caused by the oxidation of Ni. The oxidation rate of the metallic phase and the corrosion rate of the ceramic phase have an important effect on the formation of the dense layer. In the corrosion process of NiFe2O4 phase, preferential corrosion of Fe element occurs first, and then NiO phase is precipitated from NiFe2O4 phase. After the NiO is dissolved and corroded, the NiFe2O4 grains collapse and the ceramic phase peels off from the anode.
摘要：
The thermal conductivity of single-crystal silicon was investigated by using Raman spectroscopy. The laser simultaneously acted as an excitation source and a heating source. The correlations between Raman spectra with both temperature and laser power for single-crystal silicon, which has a potential relationship with the thermal conductivity, were estimated. The results showed the localized compressive stress caused by laser heating would underestimate Raman peak shift. So, the temperature was determined based on the variation of linewidth. The predicted thermal conductivity of single-crystal silicon is 125 W/m ⋅ K, which is comparable to the theoretical value.
通讯机构：
[Gan, ZJ ] N;Nanjing Univ, Nanjing Univ Med Sch, State Key Lab Pharmaceut Biotechnol, Nanjing Drum Tower Hosp,Affiliated Hosp, Nanjing, Peoples R China.;Nanjing Univ, Nanjing Univ Med Sch, MOE Key Lab Model Anim Dis Study,Dept Spine Surg, Nanjing Drum Tower Hosp,Affiliated Hosp,Model Ani, Nanjing, Peoples R China.;Nanjing Univ, Nanjing Univ Med Sch, Jiangsu Key Lab Mol Med, Nanjing, Peoples R China.;Nanjing Univ, Chem & Biomed Innovat Ctr ChemBIC, Nanjing, Peoples R China.
摘要：
Mitochondrial proteolysis is an evolutionarily conserved quality-control mechanism to maintain proper mitochondrial integrity and function. However, the physiological relevance of stress-induced impaired mitochondrial protein quality remains unclear. Here, we demonstrate that LONP1, a major mitochondrial protease resides in the matrix, plays a role in controlling mitochondrial function as well as skeletal muscle mass and strength in response to muscle disuse. In humans and mice, disuse-related muscle loss is associated with decreased mitochondrial LONP1 protein. Skeletal muscle-specific ablation of LONP1 in mice resulted in impaired mitochondrial protein turnover, leading to mitochondrial dysfunction. This caused reduced muscle fiber size and strength. Mechanistically, aberrant accumulation of mitochondrial-retained protein in muscle upon loss of LONP1 induces the activation of autophagy-lysosome degradation program of muscle loss. Overexpressing a mitochondrial-retained mutant ornithine transcarbamylase (Delta OTC), a known protein degraded by LONP1, in skeletal muscle induces mitochondrial dysfunction, autophagy activation, and cause muscle loss and weakness. Thus, these findings reveal a role of LONP1-dependent mitochondrial protein quality-control in safeguarding mitochondrial function and preserving skeletal muscle mass and strength, and unravel a link between mitochondrial protein quality and muscle mass maintenance during muscle disuse. Mitochondrial function is important for muscle maintenance and function, and mitochondrial proteolysis maintains mitochondrial integrity and function. Here the authors report that that loss of LONP1-dependent mitochondrial proteolysis in muscle causes reduced muscle mass and strength via activation of autophagy.
作者：
Tan, Tan;Wu, Chuanfen;Liu, Boye;Pan, Bih-Fang;Hawke, David H.;...
期刊：
MOLECULAR BIOLOGY OF THE CELL,2022年33(12):ar115 ISSN：1059-1524
通讯作者：
Sue-Hwa Lin<&wdkj&>Jian Kuang
作者机构：
[Tan, Tan; Kuang, Jian; Wu, Chuanfen; Wang, Ruoning] Univ Texas MD Anderson Canc Ctr, Dept Expt Therapeut, Houston, TX 77030 USA.;[Pan, Bih-Fang; Hawke, David H.] Univ Texas MD Anderson Canc Ctr, Dept Syst Biol, Houston, TX 77030 USA.;[Lin, Sue-Hwa] Univ Texas MD Anderson Canc Ctr, Dept Translat Mol Pathol, Houston, TX 77030 USA.;[Tan, Tan] Univ South China, Hengyang Med Sch, Dept Biochem & Mol Biol, Hengyang 421001, Hunan, Peoples R China.;[Liu, Boye] Beijing Normal Univ, Coll Life Sci, Key Lab Biodivers & Ecol Engn, Minist Educ, Beijing 100875, Peoples R China.
摘要：
The term M-phase supershift denotes the phosphorylation-dependent substantial increase in the apparent molecular weight of numerous proteins of varied biological functions during M-phase induction. Although the M-phase supershift of multiple key mitotic regulators has been attributed to the multisite phosphorylation catalyzed by the Cdk1/cyclin B/Cks complex, this view is challenged by multiple lines of paradoxical observations. To solve this problem, we reconstituted the M-phase supershift of Xenopus Cdc25C, Myt1, Wee1A, APC3, and Greatwall in Xenopus egg extracts and characterized the supershift-producing phosphorylations. Our results demonstrate that their M-phase supershifts are each due to simultaneous phosphorylation of a considerable portion of S/T/Y residues in a long intrinsically disordered region that is enriched in both S/T residues and S/TP motifs. Although the major mitotic kinases in Xenopus egg extracts, Cdk1, MAPK, Plx1, and RSK2, are able to phosphorylate the five mitotic regulators, they are neither sufficient nor required to produce the M-phase supershift. Accordingly, inhibition of the four major mitotic kinase activities in Xenopus oocytes did not inhibit the M-phase supershift in okadaic acid-induced oocyte maturation. These findings indicate that the M-phase supershift is produced by a previously unrecognized category of mitotic phosphorylation that likely plays important roles in M-phase induction.
作者机构：
[Yang, Rendang; Wang, Yang; Fu, Danning; Wang, Y] South China Univ Technol, State Key Lab Pulp & Paper Engn, Guangzhou 510640, Peoples R China.;[Wang, Ruibin] Univ South China, Coll Chem & Chem Engn, Hengyang 421001, Peoples R China.;[Hua, Feiguo; Hua, FG] Zhejiang Jinjiahao Green Nanomat Co Ltd, 37-1 Jinxing Ave, Quzhou 324404, Peoples R China.
通讯机构：
[Hua, FG ] Z;[Wang, Y ] S;South China Univ Technol, State Key Lab Pulp & Paper Engn, Guangzhou 510640, Peoples R China.;Zhejiang Jinjiahao Green Nanomat Co Ltd, 37-1 Jinxing Ave, Quzhou 324404, Peoples R China.
期刊：
Chemical Engineering Journal,2022年444:136397 ISSN：1385-8947
通讯作者：
Zijie Li<&wdkj&>Hongqing Wang<&wdkj&>Weiqun Shi
作者机构：
[Yuan, Liyong; Li, Zijie; Shi, Weiqun; Wang, Lin; Wang, Siyi; Tang, Xiaoyi] Chinese Acad Sci, Inst High Energy Phys, Lab Nucl Energy Chem, Beijing 100049, Peoples R China.;[Wang, Hongqing; Tang, Xiaoyi] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.;[Zhang, Zhihui] Changzhou Univ, Adv Catalysis & Green Mfg Collaborat Innovat Ctr, Jiangsu Key Lab Adv Catalyt Mat & Technol, Changzhou 213164, Peoples R China.;[Wang, Bairong; Sun, Jian] Inst NBC Denfence, Beijing 102205, Peoples R China.;[Zheng, Lirong] Chinese Acad Sci, Inst High Energy Phys, Beijing Synchrotron Radiat Facil, Beijing 100049, Peoples R China.
通讯机构：
[Zijie Li; Weiqun Shi] L;[Hongqing Wang] S;Laboratory of Nuclear Energy Chemistry, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China<&wdkj&>School of Chemistry and Chemical Engineering, University of South China, Hengyang 421001, China
关键词：
Adsorption;Cation-exchange;Cs2CuFe(CN)6;Cs+;Prussian blue analogues (PBAs)
通讯机构：
[Lin, Ying-Wu] U;Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.;Univ South China, Lab Prot Struct & Funct, Hengyang 421001, Peoples R China.
摘要：
The old dye indigo is still demanded worldwide, whereas chemical synthesis of indigo may cause environmental problems. Alternatively, the biosynthesis of indigo is an eco-friendly approach. In this study, by protein design and engineering, we showed that human neuroglobin (Ngb) can be converted into an enzyme capable of efficient synthesis of indigo from indole. Three mutations were rationally designed to stabilize the protein (A15C), enhance H2O2 activation (H64D), and facilitate electron transfer (F49Y), respectively. Kinetic studies and product analysis revealed that the triple mutant A15C/H64D/F49Y Ngb exhibits an activity much higher than those of the engineered myoglobin mutants, without the need of expensive cofactors required for cytochromes P450. This enzyme can also efficiently catalyze the coupling oxidation of indole derivatives containing -Cl/-Br/-NO2 groups, producing indigo derivative dyes, with a yield up to similar to 90% and chemoselectivity up to similar to 97%, respectively. Moreover, these synthesized dyes were successfully applied to dye cotton textiles with uniform colors such as blue, red, yellow, purple, and even green. Thus, we expect that the engineered enzyme of Ngb will have practical applications in the textile dyeing industry.
通讯机构：
[Fei Zeng] D;Department of Biology and Chemistry, Hunan University of Science and Engineering, Yongzhou 425199, China
摘要：
In this work, we design and synthesize a new macrocycle, phenanthrene[2]arene 1, with nanometer-sized cavities in high yield. The nonporous adaptive crystals of phenanthrene[2]arene exhibit excellent benzene (PhH) adsorption capacity, and one host molecule can at maximum adsorb five PhH molecules. Moreover, activated crystals of 1 are able to separate PhH from an equimolar mixture of PhH and cyclohexane (Cy) and the purity of the PhH can reach 98.4% under mild and user-friendly conditions. In addition, fast adsorption, high loading ratios, high purity, and easy recycling are achieved with the present system for the separation of PhH and Cy, which is promising for practical applications.
作者机构：
[Zhao, Yubao; Wang, Wenqin] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.;[Wang, Ruibin] Univ South China, Hunan Key Lab Design & Applicat Actinide Complexe, Hengyang 421001, Peoples R China.
通讯机构：
[Prof. Yubao Zhao] S;[Dr. Ruibin Wang] H;School of Chemistry and Chemical Engineering, University of South China, Hengyang, 421001 P.R. China<&wdkj&>Hunan Key Laboratory for the Design and Application of Actinide Complexes, University of South China, Hengyang, 421001 P.R. China
通讯机构：
[Hong Wu; Zhongyi Jiang] K;Key Laboratory for Green Chemical Technology of Ministry of Education, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China<&wdkj&>Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin 300072, China<&wdkj&>Joint School of National University of Singapore and Tianjin University, International Campus of Tianjin University, Binhai New City, Fuzhou 350207, China<&wdkj&>Zhejiang Institute of Tianjin University, Ningbo, Zhejiang 315201, China<&wdkj&>Key Laboratory for Green Chemical Technology of Ministry of Education, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China<&wdkj&>Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin 300072, China<&wdkj&>Tianjin Key Laboratory of Membrane Science and Desalination Technology, Tianjin University, Tianjin 300072, China
期刊：
Separation and Purification Technology,2022年303:122256 ISSN：1383-5866
通讯作者：
Hongqing Wang<&wdkj&>Xiangke Wang
作者机构：
[Wang, Hongqing; Wang, Shiyu] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.;[Wei, Guo] Beijing Beitou Ecoenvironm Co Ltd, Beijing, Peoples R China.;[Wang, Xiangke; Wang, Shiyu; Wei, Guo; Chen, Zhongshan; Xie, Yinghui; Shang, Hailin; Yang, Hui] North China Elect Power Univ, Coll Environm Sci & Engn, Beijing 102206, Peoples R China.;[Waterhouse, Geoffery I. N.] Univ Auckland, Sch Chem Sci, Auckland 1142, New Zealand.
通讯机构：
[Hongqing Wang] S;[Xiangke Wang] C;College of Environmental Science and Engineering, North China Electric Power University, Beijing 102206, China<&wdkj&>School of Chemistry and Chemical Engineering, University of South China, Hengyang, Hunan 421001, China
摘要：
Nuclear wastes include sludges and supernatant liquids containing toxic uranium radionuclides (235U and 238U). Concerns about the potentially hazardous impact of uranium on the environment motivate the development of new technologies for selectively removing uranium radionuclides from polluted water and groundwater. We demonstrate herein the enormous potential of covalent organic frameworks (COFs) as a low-cost platform for the construction of adsorbents for uranium radionuclide capture and nuclear waste management. Using amidoxime groups together with carbonyl electron donors as chelating sites, COFs demonstrating fast adsorption kinetics, high adsorption capacities, and selectivity toward uranyl adsorption were successfully synthesized. A particular COF, COF-DBD-AO, was capable of rapidly decontaminating uranium-contaminated potable water to drinking water levels within 120 min. The presence of nearby carbonyl groups improved the affinity of amidoxime groups for uranyl ions, thus enhancing the selectivity for uranyl ion adsorption over other common cations.
作者机构：
[Zhu, Xuebin; Liu, Miao; Yang, Bingbing; Huang, Hui] Chinese Acad Sci, Inst Solid State Phys, Hefei 230031, Peoples R China.;[Jin, Linghua; Yang, BB] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.;[Liu, Miao] Univ Sci & Technol China, Hefei 230026, Peoples R China.;[Yang, Bingbing] Foshan Southern China Inst New Mat, Foshan 528200, Peoples R China.
通讯机构：
[Jin, LH; Yang, BB] U;Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.
关键词：
Bi7Fe2NiTi3O21 thin films;Magnetic field annealing;Ferroelectric;Magnetic
摘要：
In this work, solution derived Aurivillius Bi7Fe2NiTi3O21 (BFNTO) thin films were prepared by in-situ magnetic annealing. The evolution of structure, ferroelectric and magnetic properties were systematically studied. As the increase of annealing magnetic field to 4 Tesla, the ferroelectric properties were improved with a larger intrinsic remnant polarization of 12.4 mu C/cm(2). The magnetic properties were substantially improved with remnant magnetization from 1.4 to 3.2 emu/cm(3) as the annealing magnetic field increases from 0 to 6 Tesla. These results indicate that in-situ magnetic annealing is an effective method to optimize ferroelectric and magnetic properties of multiferroics.
作者机构：
[Wu, Qun-Yan; Ye, Zi-Rong; Chai, Zhi-Fang; Wang, Cong-Zhi; Lan, Jian-Hui; Shi, Wei-Qun] Chinese Acad Sci, Inst High Energy Phys, Lab Nucl Energy Chem, Beijing 100049, Peoples R China.;[Ye, Zi-Rong; Wang, Hong-Qing] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.
通讯机构：
[Qun-Yan Wu; Wei-Qun Shi] L;[Hong-Qing Wang] S;Laboratory of Nuclear Energy Chemistry, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China<&wdkj&>School of Chemistry and Chemical Engineering, University of South China, Hengyang 421001, China
作者机构：
[Wang, Huamin; Wei, Yibo; Lin, Ying-Wu; Li, Shixiong; Long, Shuangshuang] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.;[Li, Yuqiang] Cent South Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China.;[Sun, Li-Juan] Univ South China, Hengyang Med Coll, Hengyang 421001, Hunan, Peoples R China.;[Lin, Ying-Wu] Univ South China, Lab Prot Struct & Funct, Med Sch, Hengyang 421001, Hunan, Peoples R China.
通讯机构：
[Huamin Wang; Ying-Wu Lin] S;School of Chemistry and Chemical Engineering, University of South China, Hengyang, Hunan 421001, People’s Republic of China<&wdkj&>Hengyang Medical College, University of South China, Hengyang, Hunan 421001, People’s Republic of China<&wdkj&>Laboratory of Protein Structure and Function, University of South China Medical School, Hengyang, Hunan 421001, People’s Republic of China<&wdkj&>School of Chemistry and Chemical Engineering, University of South China, Hengyang, Hunan 421001, People’s Republic of China
摘要：
Herein, a new strategy for the enantioselective synthesis of axially chiral N-aryl succinimides was devised by [3 + 2] annulation of MBH carbonates and N-aryl maleimides under chiral phosphine. This desymmetrization process allows for quick construction of both two stereogenic carbon centers and a remote CAr–N atropisomeric chirality. A series of structurally diverse N-aryl succinimides were obtained with good to excellent yields, diastereoselectivities, and enantioselectivities. The process is mild, efficient, and scalable and features a broad substrate scope.
通讯机构：
[Ke-Jie Du; Ying-Wu Lin] S;School of Chemistry and Chemical Engineering, Laboratory of Protein Structure and Function, Hunan Key Laboratory for the Design and Application of Actinide Complexes, University of South China, Hengyang 421001, China
摘要：
Heme proteins have recently emerged as promising artificial metalloenzymes for catalyzing diverse reactions. In this report, L29E Mb, a single mutant of myoglobin (Mb), was reconstituted by replacing the heme with a sodium copper cholorophyllin (CuCP) to form a new green artificial enzyme (named CuCP-L29E Mb). The reconstituted protein CuCP-L29E Mb was found to exhibit hydrolytic DNA cleavage activity, which was not depending on O(2). In addition, Mg(2+) ion could effectively promote the DNA cleavage activity of CuCP-L29E Mb. Wild-type (WT) Mb reconstituted with CuCP (named CuCP-WT Mb) did not show DNA cleavage activity under the same conditions. This study suggests that both Mg(2+) and the ligand Glu29 are critical for the nuclease activity and the artificial nuclease of Mg(2+)-CuCP-L29E Mb may have potential applications in the future.
