The molecular mechanisms of chemotherapeutic resistance in tumors (Review)

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Weng, Xin;Zeng, Wei-Hong;Zhong, Li-Yuan;Xie, Li-Hua;Ge, Wen-Jun;...

通讯作者：

Zeng, X

作者机构：

[Qin, Qin; Zhong, Li-Yuan; Zeng, Xi; Weng, Xin; Cao, De-Liang; Xie, Li-Hua; Ge, Wen-Jun] Univ South China, Canc Res Inst, Hunan Engn Res Ctr Early Diag & Treatment Liver Ca, Hengyang Med Sch,Hunan Prov Key Lab Tumor Cellular, 28 Changsheng West Rd, Hengyang 421001, Hunan, Peoples R China.

[Zeng, Wei-Hong] Hunan Normal Univ, Coll Life Sci, Lab Mol & Stat Genet, Changsha 410081, Hunan, Peoples R China.

[Lai, Zhen] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Pathol, Hengyang 421001, Hunan, Peoples R China.

[Liu, Peng] Hunan Normal Univ, Affiliated Hosp 1, Peoples Hosp, Dept Gastroenterol, Changsha 410005, Hunan, Peoples R China.

通讯机构：

[Zeng, X ] U

Univ South China, Canc Res Inst, Hunan Engn Res Ctr Early Diag & Treatment Liver Ca, Hengyang Med Sch,Hunan Prov Key Lab Tumor Cellular, 28 Changsheng West Rd, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

cellular dormancy;chemotherapy resistance;multidrug resistance;tumors

期刊：

ONCOLOGY REPORTS

ISSN：

1021-335X

年：

2024

卷：

期：

DOI：

10.3892/or.2024.8816

基金类别：

Natural Science Foundation of Hunan Province

机构署名：

本校为第一且通讯机构

院系归属：

医学院

摘要：

Chemotherapy remains a prevalent treatment for a wide range of tumors; however, the majority of patients undergoing conventional chemotherapy experience varying levels of chemoresistance, ultimately leading to suboptimal outcomes. The present article provided an in‑depth review of chemotherapy resistance in tumors, emphasizing the underlying factors contributing to this resistance in tumor cells. It also explored recent advancements in the identification of key molecules and molecular m...

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