期刊论文

Feasibility of automatic IMRT planning for cervical cancer based on a database of previously-treated patients

中文

中华放射肿瘤学杂志

1004-4221

2020

29

02

141-145

10.3760/cma.j.issn.1004-4221.2020.02.014

(2017-ZQN-15,2018-ZQN-19,2017-CX-8):福建省卫生健康科技项目 (2018Y2003):福建省科技计划项目 (2017-ZQN-15,2018-ZQN-19,2017-CX-8):Fujian Provincial Health Technology Project (2018Y2003):Science and Technology Program of Fujian Province

本校为其他机构

目的基于重叠体积直方图(OVH)和优质宫颈癌IMRT计划数据库,研究并评估宫颈癌IMRT自动计划的可行性。方法选取200例宫颈癌患者的优质IMRT计划和OVH,建立OVH和优质计划数据库。另选取26例宫颈癌病例作为测试病例,自编程序实现OVH数据至图像转化及图像相似度计算。选取图像相似度最高的数据库病例的计划优化函数,结合Pinnacle3计划系统脚本实现自动计划设计。比较自动计划和手工计划的剂量学参数、计划质量和设计时间。结果与手工计划相比,自动计划的靶区覆盖、适形性、均匀性相当(P>0.05);直肠V_(40)、V_(45)和平均剂量分别下降了6.1%、1.3%和50. 7 cGy(P

Objective To develop and evaluate an automatic intensity-modulated radiation therapy (IMRT) program for cervical cancer based on a database of overlap volume histogram ( OVH) and highquality cervical IMRT plans for previously-treated patients. Methods A database consisting of high-quality IMRT plans and OVHs from 200 cervical cancer patients was established. OVHs of another 26 cervical cancer patients were converted into gray level images to calculate the image similarity compared with those from the database. The planning optimization function of the patients from the database with the highes...