期刊论文

Application of EPID-based 3D dose reconstruction in cancer patients

中文

中华放射肿瘤学杂志

1004-4221

2018

27

11

984-988

10.3760/cma.j.issn.1004-4221.2018.11.007

浙江省医药卫生科技计划（2017PY014）~~；

本校为其他机构

目的基于EPID利用Edose软件重建三维剂量分布,帮助放疗工作人员更好地了解治疗期间患者相关危及器官和靶区的剂量变化情况。方法对头颈部肿瘤和胸部肿瘤患者治疗前行1次/周总共6次CBCT扫描,将CBCT图像与计划CT图像进行刚性配准后传入到Edose剂量分析软件中,利用Edose软件根据摆位误差基于EPID对其进行三维剂量重建,最后分析不同危及器官剂量并比较γ通过率。结果与原计划剂量相比,鼻咽癌患者脊髓D_(max)分次间受量波动较大且高于患者原计划剂量,脑干D_(max)分次间受量变化较小,左右腮腺V30所受剂量变化较大,单次增加幅度最高可达28.69%;胸部肿瘤患者脊髓D_(max)差异较小,肺与心脏实际受量都高于...

Objective To perform 3D dose reconstruction based on electronic portal imaging device (EPID) of linear accelerator for the static intensity-modulated using Edose, a dose verification system, Aiming to assist the radiotherapy professionals to better understand the radiotherapy organs at risk and target dose changes. Methods CBCT image was acquired for patients with head and neck cancer and thoracic cancer once a week for a total of six times. Subsequently,CBCT images and planning CT images were subject to rigid registration and exported to the Edose software. According to the setup error, EPID-...