期刊论文

中文

中华放射肿瘤学杂志

1004-4221

2012

21

2

168-171

10.3760/cma.j.issn.1004-4221.2012.02.022

本校为其他机构

目的探讨调强放疗计划中机架角度优化的剂量学特点.方法随机选取15例脑胶质瘤术后患者,每例患者分别设计两种治疗计划,其中射野数目(5~9个野)、剂量体积约束条件相同,但第1种计划(计划1)的机架按等角度共面布置,第2种计划(计划2)的机架角由计划系统内含的机架角度几何优化算法自动选择.在处方剂量要求相同情况下,比较两种计划的靶区和危及器官剂量学参数、机器跳数差异.结果靶区剂量学参数中,计划1的计划瘤床体积适形指数好于计划2(0.84∶0.85,=2.77,P=0.015)；对于危及器官,计划2的左右晶体和左视神经受量明显低于计划1(528.91 cGy∶ 662.40%,t=3.15,P=0.007;535.87 cGy∶ 631.99 cGy,t=2.72,P...

Objective To compare the dosimetric characteristics of intensity-modulated radiotherapy (IMRT) treatment plan with gantry orientation optimization. Methods Fifteen post-operation patients with brain glioma were selected randomly. Two plans were designed for each patient with the same dose-volume constraints and number of fields (from 5 t0 9 fields). A standard coplanar equi-space gantry angles were used in the first plan ( plan 1) , whereas the selection of gantry angle was optimized by plan geometry optimization algorithm for the same number o...