MiR-493 suppresses the proliferation and invasion of gastric cancer cells by targeting RhoC

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhou, Wenhua;Zhang, Chi;Jiang, Hao;Zhang, Zhiwei;Xie, Liming;...

通讯作者：

He, Xiusheng

作者机构：

[Zhou, Wenhua; Zhang, Zhiwei; He, Xiusheng] Univ South China, Canc Res Inst, Key Lab Canc Cellular & Mol Pathol Hunan Prov Uni, Hengyang 421001, Peoples R China.

[Zhang, Chi] Univ South China, Sch Med, Funct Lab Ctr, Hengyang 421001, Hunan, Peoples R China.

[Xie, Liming; Jiang, Hao] Univ South China, Affiliated Hosp 1, Ctr Gastr Canc Res Human Prov, Hengyang 421001, Hunan, Peoples R China.

[He, Xiusheng] Univ South China, Canc Res Inst, 28 West Changsheng Rd, Hengyang 421001, Peoples R China.

通讯机构：

[He, Xiusheng] U

Univ South China, Canc Res Inst, 28 West Changsheng Rd, Hengyang 421001, Peoples R China.

语种：

英文

关键词：

Gastric cancer;Invasion;Prognostic significance;Proliferation;miR-493

期刊：

IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES

ISSN：

2008-3866

年：

2015

卷：

期：

页码：

1027-1033

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81172575, 30470668. 81100106]

机构署名：

本校为第一且通讯机构

院系归属：

医学院

摘要：

Objective(s): MiRNAs have been proposed to be key regulators of tumorigenesis, progression and metastasis. However, their effect and prognostic value in gastric cancer is still poorly known. Materials and Methods: Gastric cancer cell lines were cultured. Tissue samples obtained from 36 gastric cancer patients were used for quantitative real‐time PCR (qRT‐PCR) analysis. The tissue microarrays (TMAs) consisted of 126 cases of gastric carcinoma that were used for In situ hybridisation (ISH). Lentivirus plasmids were co‐transfected into 293FT ce...

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MiR-493 suppresses the proliferation and invasion of gastric cancer cells by targeting RhoC

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