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Network pharmacology analysis revealed the mechanism and active compounds of jiao tai wan in the treatment of type 2 diabetes mellitus via SRC/PI3K/AKT signaling

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成果类型:
期刊论文
作者:
Ye, Cunsi;Li, Yumeng;Shi, Jiayin;He, Liena;Shi, Xinyan;...
通讯作者:
Xiaopeng Lan
作者机构:
[Shi, Jiayin; Li, Yumeng; Lei, Wenbo; Ye, Cunsi; He, Liena; Shi, Xinyan; Yang, Wei] Department of Clinical Laboratory Medicine, Institution of Microbiology and Infectious Diseases, Hunan Province Clinical Research Center for Accurate Diagnosis and Treatment of High-incidence Sexually Transmitted Diseases, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hunan, China
[Quan, Shijian] School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China
[Lan, Xiaopeng] Department of Clinical Laboratory Medicine, Institution of Microbiology and Infectious Diseases, Hunan Province Clinical Research Center for Accurate Diagnosis and Treatment of High-incidence Sexually Transmitted Diseases, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hunan, China. Electronic address: Lanxp@sina.com
[Liu, Shuangquan] Department of Clinical Laboratory Medicine, Institution of Microbiology and Infectious Diseases, Hunan Province Clinical Research Center for Accurate Diagnosis and Treatment of High-incidence Sexually Transmitted Diseases, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hunan, China. Electronic address: dantelliu@163.com
通讯机构:
[Xiaopeng Lan] D
Department of Clinical Laboratory Medicine, Institution of Microbiology and Infectious Diseases, Hunan Province Clinical Research Center for Accurate Diagnosis and Treatment of High-incidence Sexually Transmitted Diseases, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hunan, China
语种:
英文
关键词:
Insulin resistance;Jiao-tai-wan;Lipid metabolism;Proto-oncogene tyrosine-protein kinase SRC (SRC);Type 2 diabetes mellitus (T2DM)
期刊:
Journal of Ethnopharmacology
ISSN:
0378-8741
年:
2025
卷:
337
期:
Pt 2
页码:
118898
机构署名:
本校为第一且通讯机构
摘要:
Ethnopharmacological relevance Jiao-tai-wan (JTW) is a traditional Chinese herbal prescription, exerts its therapeutic effects on type 2 diabetes mellitus (T2DM). However, its mechanisms and active components remain unclear. Jiao-tai-wan (JTW) is a traditional Chinese herbal prescription, exerts its therapeutic effects on type 2 diabetes mellitus (T2DM). However, its mechanisms and active components remain unclear. Aim of the study To investigate the therapeutic mechanisms of JTW in treating type 2 diabetes mellitus (T2DM), focusing on identify...

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