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Curcumin reduces myocardial damage and improves antioxidant capacity of myocardial tissue in diabetic rats

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成果类型:
期刊论文
作者:
Yan, Wei;Xiong, Wei;Hu, Qingpeng;Qiu, Mali*
通讯作者:
Qiu, Mali
作者机构:
[Yan, Wei; Qiu, Mali; Xiong, Wei] Cent S Univ, Xiangya Hosp 2, Dept Cardiovasc Surg, 139 Renminzhong Rd, Changsha, Hunan, Peoples R China.
[Hu, Qingpeng] Univ South China, Affiliated Hosp 2, Dept Pediat, Hengyang, Hunan, Peoples R China.
通讯机构:
[Qiu, Mali] C
Cent S Univ, Xiangya Hosp 2, Dept Cardiovasc Surg, 139 Renminzhong Rd, Changsha, Hunan, Peoples R China.
语种:
英文
关键词:
Curcumin;diabetes;myocardial damage;antioxidant capacity
期刊:
International Journal of Clinical and Experimental Medicine
ISSN:
1940-5901
年:
2019
卷:
12
期:
7
页码:
8879-8886
机构署名:
本校为其他机构
摘要:
Objective: To investigate the effects of curcumin on myocardial damage and its antioxidant capacity in myocardial tissue of diabetic rats. Methods: A rat model of diabetic heart disease was established. 3 Thirty adult male SD rats were randomly and equally divided into the blank group, the diabetic group, and the curcumin group. Starting with successful modeling, 200 mg/kg of curcumin suspension was given to the rats per day by intragastric administration. The rats in the blank group and the diabetic group were given normal saline daily and all treatments lasted 4 weeks. The systolic blood pre...

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