Objective To isolate and analyze the anti-cancer constituents in Onychium lueidum. Methods Five flavonoids compounds were isolated from the herbs of Onychium. We investigated the effect of the flavonoids on HT-29 and SGC-7901 cell lines through the MTT assay. Results The flavonoids had significant anti- proliferaive effect on HT-29 and SGC-7901 eel1 lines. Conclusion The flavonoids isolated fi'om ...