期刊论文

Li, Kai

英文

Molecular Biotechnology

1073-6085

2010

162

2

321-328

10.1007/s12010-009-8793-7

Acknowledgments The authors are indebt to Dr. Gabriel Gutiérrez at Departamento de Genética, Universidad de Sevilla, Sevilla, Spain for proofreading this manuscript. This paper is partially supported by Department of Personnel Jiangsu province “Liu Da Ren Cai Gao Feng” grant (07-B-033), and The National Natural Science Foundation of China (No. 30970877).

本校为其他机构

Indels in evolutionary studies are rapidly decayed obeying a power law. The present study analyzed the length distribution of small insertions and deletions associated with human diseases and confirmed that the decay pattern of these small mutations is similar to that of indels when the mutation datasets are large enough. The describable decay pattern of somatic mutations may have application in the evaluation of varied penetrance of different mutations and in association study...