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Failure to seroconvert after three doses of inactivated COVID-19 vaccines in a patient co-infected with HBV and HIV: A case report

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成果类型:
期刊论文
作者:
Zeng, Guang;Tang, Jie;Feng, Shuidong;Xu, Liumei;Wang, Xiaohui;...
通讯作者:
Zhengrong Yang
作者机构:
[Yang, Zhengrong; Zeng, Guang; Wang, Xiaohui] Shenzhen Ctr Dis Control & Prevent, Dept HIV AIDS Prevent & Control, Shenzhen, Peoples R China.
[Yang, Zhengrong; Zeng, Guang; Feng, Shuidong; Tang, Jie] Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hengyang, Peoples R China.
[Xu, Liumei] Third Peoples Hosp Shenzhen, Natl Clin Res Ctr Infect Dis, Shenzhen, Peoples R China.
通讯机构:
[Zhengrong Yang] D
Department of HIV/AIDS Prevention and Control, Shenzhen Center for Disease Control and Prevention, Shenzhen, China<&wdkj&>School of Public Health, Hengyang Medical School, University of South China, Hengyang, China
语种:
英文
关键词:
CD4+T cell count;HIV/HBV co-infection;inactivated COVID-19 vaccine;people living with HIV;spike receptor binding domain IgG (S-RBD-IgG) antibody;viral load (VL)
期刊:
Human Vaccines & Immunotherapeutics
ISSN:
2164-5515
年:
2022
卷:
18
期:
6
页码:
Article: 2110799
基金类别:
This study was supported by Guangdong Provincial Basic and Applied Basic Research Foundation [2019B1515120003]; Shenzhen Municipal Science and Technology Innovation Committee Foundation [JCYJ20180508152244835].
机构署名:
本校为其他机构
院系归属:
公共卫生学院
摘要:
In the global context of the COVID-19 pandemic, the overall benefits of getting any COVID-19 vaccine approved by the World Health Organization for emergency use outweigh the potential risks, even in people with weakened immune systems, including people living with HIV (PLWH). At present, there are no reports of HIV/hepatitis B virus (HBV) co-infected patients receiving a booster dose of the inactivated COVID-19 vaccine. Here, we describe a patient with HIV/HBV co-infection who did not ser...

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