[Huang, Shifang; Lv, Deguan; Luo, Xuling; Zhou, Qionglin; Tang, Mingzhu; Huang, Zheng; Luo, XL; Li, Lanfang; Chen, Linxi; Lu, Liqun; Xu, Jin; He, Lu; Zhou, Hong] Univ South China, Inst Pharm & Pharmacol, Prov Cooperat Innovat Ctr Mol Target New Drug Stu, Learning Key Lab Pharmacoprote, Hengyang, Peoples R China.

[He, Lu] Univ South China, Affiliated Hosp 1, Dept Neurosurg, Hengyang, Peoples R China.

[Zhong, Jiuchang] Capital Med Univ, Heart Ctr, Beijing Chaoyang Hosp, Beijing, Peoples R China.

[Zhong, Jiuchang] Capital Med Univ, Beijing Key Lab Hypertens, Beijing Chaoyang Hosp, Beijing, Peoples R China.

[Chen, Jian-xiong] Univ Mississippi, Med Ctr, Dept Pharmacol & Toxicol, Jackson, MS 39216 USA.

[Luo, XL; Li, LF; Chen, LX] U

Univ South China, Inst Pharm & Pharmacol, Prov Cooperat Innovat Ctr Mol Target New Drug Stu, Learning Key Lab Pharmacoprote, Hengyang, Peoples R China.

apelin;apelin 13;apolipoprotein E;beclin 1;cycline;dynamin related protein 1;parkin;pink1 protein;protein;sequestosome 1;unclassified drug;apelin-13 peptide;hydroxymethylglutaryl coenzyme A reductase kinase;parkin;protein kinase;PTEN-induced putative kinase;signal peptide;ubiquitin protein ligase;age;AMPK signaling;animal cell;animal experiment;aortic wall;Article;atherosclerosis;atherosclerotic plaque;autophagosome;autopsy;cell activity;cell proliferation;coronary artery;diabetes mellitus;disease exacerbation;enzyme linked immunosorbent assay;human;human cell;hyperlipidemia;hypertension;immunohistochemistry;in vitro study;in vivo study;mitochondrial dynamics;mitochondrion;mitophagy;mouse;nonhuman;priority journal;protein expression;rat;sex;smoke;transmission electron microscopy;vascular smooth muscle cell;animal;aortic disease;apolipoprotein E knockout mouse;atherosclerosis;C57BL mouse;case control study;cell culture;cell proliferation;disease model;drug effect;enzymology;genetics;male;metabolism;mitophagy;muscle mitochondrion;pathology;phosphorylation;signal transduction;smooth muscle cell;ultrastructure;vascular smooth muscle;AMP-Activated Protein Kinases;Animals;Aortic Diseases;Atherosclerosis;Case-Control Studies;Cell Proliferation;Cells, Cultured;Disease Models, Animal;Humans;Intercellular Signaling Peptides and Proteins;Male;Mice, Inbred C57BL;Mice, Knockout, ApoE;Mitochondria, Muscle;Mitophagy;Muscle, Smooth, Vascular;Myocytes, Smooth Muscle;Phosphorylation;Plaque, Atherosclerotic;Protein Kinases;Signal Transduction;Ubiquitin-Protein Ligases

药学与生物科学学院