会议论文

Jun, Yang

英文

ELECTRICAL AND CONTROL ENGINEERING & MATERIALS SCIENCE AND MANUFACTURING

2016

477-482

Joint Conference of 6th International Congress on Electrical and Engineering (ICECE) / 4th International Conference on Material Science and Manufacturing (ICMSM)

AUG 14-15, 2015

Shanghai, PEOPLES R CHINA

[Wu Zhixiong;Jian, Luo;Fang, Li;Ting, Xiao;Ou, Zeng;Chun, Chu;Jun, Yang] Univ South China, Affiliated Hosp 1, Dept Cardiol, Hengyang 421001, Peoples R China.

Qin, S Li, X

PO BOX 128 FARRER RD, SINGAPORE 9128, SINGAPORE

WORLD SCIENTIFIC PUBL CO PTE LTD

978-981-310-031-2; 978-981-310-030-5

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81270181]; Hunan Provincial Natural Science Foundation of ChinaNatural Science Foundation of Hunan Province [11JJ2046]

本校为第一且通讯机构

Objective: To investigate the different effects of gefitinib, as a new stent coating material, on proliferation of vascular smooth muscle cells (VSMCs) and endothelial cells (ECs) compared with those of paclitaxel. Methods: Cultured VSMCs and ECs were treated with different concentrations of gefitinib and paclitaxel respectively (24h, 48h, and 72h). MTT was used to detect the growth inhibition rate of cells. Western-blot analysis was used to analyze the protein levels of EGFR and p-EGFR. Results: The low concentration of paclitaxel and gefitinib had the same inhibition rate on VSMCs at the sam...