iTRAQ-Based Proteomic Profiling of Potential Biomarkers in Rat Serum for Uranium Tailing Suspension Intratracheal Instillation

首页 > 成果 > 详情

认领

导出

下载 Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Yi, Lan;Cui, Jian;Hu, Nan;Li, Linwei;Chen, Yonglin;...

通讯作者：

Ding, Dexin

作者机构：

[Yin, Jie; Wei, Yuanyun; Yi, Lan; Wei, Shuang; Mu, Hongxiang; Liu, Bang; Chen, Yonglin; Gong, Yaqi; Cui, Jian; Li, Linwei] Univ South China, Hengyang Key Lab Cellular Stress Biol, Key Discipline Lab Natl Def Biotechnol Uranium Mi, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Hengyang 421001, Hunan, Peoples R China.

[Yin, Jie; Wei, Yuanyun; Yi, Lan; Wei, Shuang; Mu, Hongxiang; Liu, Bang; Chen, Yonglin; Gong, Yaqi; Cui, Jian; Li, Linwei] Univ South China, Hengyang Med Coll, Inst Cytol & Genet, Hengyang 421001, Hunan, Peoples R China.

[Ding, Dexin; Hu, Nan] Univ South China, Hengyang Key Lab Cellular Stress Biol, Key Discipline Lab Natl Def Biotechnol Uranium Mi, Hengyang 421001, Hunan, Peoples R China.

通讯机构：

[Ding, Dexin] U

Univ South China, Hengyang Key Lab Cellular Stress Biol, Key Discipline Lab Natl Def Biotechnol Uranium Mi, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

iTRAQ;biomarkers;intra-tracheal instillation;uranium tailings

期刊：

JOURNAL OF PROTEOME RESEARCH

ISSN：

1535-3893

年：

2021

卷：

期：

页码：

995-1004

DOI：

10.1021/acs.jproteome.0c00766

基金类别：

Hunan Natural Science FoundationNatural Science Foundation of Hunan Province [2019JJ40238]; Defense Industrial Technology Development Program [JCKY2016403C001]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81400117]; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2014 M562115]; Research Initiation Funding of University of South China for the Returned Scholars from Abroad [2014XQD46]; University Students Study and Innovation Pilot Project [X2019132]

机构署名：

本校为第一且通讯机构

院系归属：

核资源工程学院

药学与生物科学学院

摘要：

Protection against low-dose ionizing radiation is of great significance. Uranium tailings are formed as a byproduct of uranium mining and a potential risk to organisms. In this study, we identified potential biomarkers associated with exposure to low-dose radiation from uranium tailings. We established a Wistar rat model of low dose rate irradiation by intratracheal instillation of a uranium tailing suspension. We observed pathological changes in the liver, lung, and kidney tissues of the rats. Using isobaric tags for relative and absolute quantification, we screened 17 common differentially e...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

iTRAQ-Based Proteomic Profiling of Potential Biomarkers in Rat Serum for Uranium Tailing Suspension Intratracheal Instillation

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问