Infrequent ERBB2 mutations in Chinese patients with non-small cell lung cancer

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成果类型：

期刊论文

作者：

Feng, Shuidong;Ling, Hongyan;Guo, Hui;Tong, Lingling;Hu, Guobin;...

通讯作者：

Tan, Hongzhuan

作者机构：

[Liao, Li; Tong, Lingling; Lv, Xueying; Feng, Shuidong] Univ South China, Basic Med Postdoctoral Res Stn, Hengyang 421001, Peoples R China.

[Liao, Li; Tong, Lingling; Lv, Xueying; Feng, Shuidong] Univ South China, Sch Publ Hlth, Dept Epidemiol & Hlth Stat, Hengyang 421001, Peoples R China.

[Ling, Hongyan] Univ South China, Sch Med, Dept Physiol, Hengyang 421001, Peoples R China.

[Hu, Guobin; Guo, Hui] Tumor Hosp Hunan Prov, Dept Pathol, Changsha 410008, Hunan, Peoples R China.

[Tan, Hongzhuan] Cent S Univ, Sch Publ Hlth, Dept Epidemiol & Hlth Stat, Changsha 410008, Hunan, Peoples R China.

通讯机构：

[Tan, Hongzhuan] C

Cent S Univ, Sch Publ Hlth, Dept Epidemiol & Hlth Stat, 110 Xiangya Rd, Changsha 410008, Hunan, Peoples R China.

语种：

英文

关键词：

ERBB2/HER2;molecular;mutation;non-small cell lung cancer (NSCLC)

期刊：

JOURNAL OF THORACIC DISEASE

ISSN：

2072-1439

年：

2014

卷：

期：

页码：

503-506

DOI：

10.3978/j.issn.2072-1439.2014.03.20

基金类别：

Postdoctoral Foundation of ChinaChina Postdoctoral Science Foundation [2012M511735]; Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [10JJ6046]

机构署名：

本校为第一机构

院系归属：

医学院

公共卫生学院

摘要：

ERBB2 mutations have been reported to occur in a subset of patients with lung adenocarcinomas or lung squamous cell carcinomas for some ethnicities, but it is unclear for Chinese patients with lung squamous cell carcinomas up to now. We retrospectively evaluated the status of ERBB2 mutations in a large cross-sectional cohort of 212 Chinese patients with non-small cell lung cancer (NSCLC) diagnosed in several hospitals from southern China during a time period of 1.5 years by polymerase chain reaction (PCR)- based direct sequencing and PCR-single...

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Infrequent ERBB2 mutations in Chinese patients with non-small cell lung cancer

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