[Liao, Duan-Fang; Zheng, Xing] Hunan Univ Chinese Med, Div Stem Cell Regulat & Applicat, State Key Lab Chinese Med Powder & Med Innovat Hu, Changsha 410208, Hunan, Peoples R China.
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81273537]; Scientific Research Fund of Hunan Provincial Education DepartmentHunan Provincial Education Department [12K095]; Ministry of Education of the People's Republic of ChinaMinistry of Education, China [20809]
机构署名：
本校为第一且通讯机构
院系归属：
药学与生物科学学院
摘要：
A series of trifluoromethylated aurone derivatives were synthesized, and the structure of 6-hydroxy-4-trifluoromethylated aurone was determined by single crystal X-ray analysis. Their anticancer activities against leucocythemia (HL-60) and colorectal adenocarcinoma (HT-29) were evaluated by the standard MTT method in vitro with 5-fluorouracil as a positive contrast drug. The results showed that all the (Z)-trifluoromethylated auron...
