版权说明 操作指南
首页 > 成果 > 详情

Multidimensional treatment of periprosthetic joint infection using fusion peptide-grafted chitosan coated porous tantalum scaffold

认领
导出
Link by DOI
反馈
分享
QQ微信 微博
成果类型:
期刊论文
作者:
Liu, Wenbin;Zhang, Kai;Sun, Yan;Xiao, Zhenyang;Hu, Hongkun;...
通讯作者:
Wenbin Liu
作者机构:
Department of Orthopaedics, The Third Xiangya Hospital Central South University, Changsha, China
[Sun, Yan] Department of Orthopedics, The First Affiliated Hospital, Medical College of Zhejiang University, Hangzhou, China
[Zhang, Kai; Hu, Hongkun; Xiong, Zixuan] Department of Orthopedic Surgery, Hunan Engineering Research Center of Biomedical Metal and Ceramic Implants, Xiangya Hospital, Central South University, Changsha, China
[Xiao, Zhenyang] Department of Medical and Aesthetic Center, Hunan Provincial Maternal and Child Health Care Hospital, University of South China, Changsha, China
[Liu, Wenbin] Department of Orthopaedics, The Third Xiangya Hospital Central South University, Changsha, China<&wdkj&>Department of Orthopedic Surgery, Hunan Engineering Research Center of Biomedical Metal and Ceramic Implants, Xiangya Hospital, Central South University, Changsha, China
通讯机构:
[Wenbin Liu] D
Department of Orthopaedics, The Third Xiangya Hospital Central South University, Changsha, China<&wdkj&>Department of Orthopedic Surgery, Hunan Engineering Research Center of Biomedical Metal and Ceramic Implants, Xiangya Hospital, Central South University, Changsha, China
语种:
英文
关键词:
Porous tantalum;Fusion peptide;Periprosthetic joint infection;Bone repair;Angiogenic-osteogenic coupling
期刊:
生物活性材料
ISSN:
2452-199X
年:
2025
卷:
44
页码:
15-33
机构署名:
本校为其他机构
摘要:
Bacterial infection and delayed osteointegration are two major challenges for orthopedic implants. Surface modification enables the implant have a time-sequenced biological function of effective antibacterial in the early stage and stable osteogenesis in the later stage, which is expected to achieve the purpose of preventing infection and prosthetic loosening after implant surgery. This study aims to construct a composite coating of carboxymethyl chitosan (CCS) grafted with an antibacterial (HHC36) and angiogenic (FP) fusion peptide (FP) on the surface of 3D-printed porous tantalum (Ta-CCS@FP)...

反馈

验证码:
看不清楚,换一个
确定
取消

成果认领

标题:
用户 作者 通讯作者
请选择
请选择
确定
取消

提示

该栏目需要登录且有访问权限才可以访问

如果您有访问权限,请直接 登录访问

如果您没有访问权限,请联系管理员申请开通

管理员联系邮箱:yun@hnwdkj.com