期刊论文

中文

世界华人消化杂志

1009-3079

1997

11

689-690

湖南省卫生厅湖南省教委科研基金

本校为第一机构

目的 观察甲基硝基亚硝基胍（ＭＮＮＧ）诱发Ｗｉｓｔａｒ大鼠胃腺癌（ＧＣ）和癌前病变（ＰＬ）过程中外周血淋巴细胞（ＰＢＬ）微核率（ＭＮＦ）的动态变化及大蒜的影响。方法 ＭＮＮＧ组（ＭＧ）３０只，预防组（ＰＧ）３０只与治疗组（ＴＧ）２０只给予ＭＮＮＧ１．２５ｍｇ／５ｍｌ／ｄ诱发大鼠ＧＣ及ＰＬ，ＰＧ另给１０％大蒜（ＧＪ）１０ｍｌ／ｄ。１０个月后，ＰＧ与ＴＧ继续给１０％ＧＪ１０ｍｌ／ｄ，对照组（ＣＧ）与Ｍ

IM To investigate the effects of garlic on micronuclei frequency (MNF) of peripheral blood lymphocytes (PBL) in gastric carcinoma (GC) and precancerous lesion (PL) in Wistar rats induced by NmethylN′nitroNnitrosoguanidine (MNNG). METHODS Gastric carcinoma and precancerous lesions were induced by MNNG 125mg/5ml per day for 10 months. 10% garlic 10ml per day were given to the experimental group, and running water to control group. MNF of PBL in the control CG (n=16), MNNG (n=30), prevention (n=30) and treatment groups (...