期刊论文

Wang, Guixue

英文

Annals of Biomedical Engineering

0090-6964

2013

41

3

611-618

10.1007/s10439-012-0677-2

This work is supported by grants from the National Key Technology R&D Program of China (2012BAI18B02), Science and Technology Innovative Research Team in Higher Educational Institutions of Hunan Province and Visiting Scholar Foundation of Key Laboratory of Biorheological Science and Technology (Chongqing University), Ministry of Education as well as the Public Experiment Center of State Bio-industrial Base (Chongqing), China.

本校为第一机构

Atherosclerosis is an inflammatory disease of large and medium sized arteriole walls that is precipitated by elevated levels of low-density lipoprotein (LDL) cholesterol in the blood. However, the mechanisms that lead to the initiation of atherosclerosis are not fully understood. In this study, endothelial cells (ECs) were incubated with LDL for 24 h, and then the lipid was detected with Oil Red O staining and cholesterol ester was assayed with high-performance liquid chromatography (HPLC). F-actin was examined by fluorescence microscopy and the viscoelasticity of ECs was investigated using th...