期刊论文

Metabolic pathways of innate lymphoid cells and regulation of their own plasticity

中文

中南医学科学杂志

2095-1116

2024

52

4

517-522

10.15972/j.cnki.43-1509/r.2024.04.004

国家自然科学基金项目(82372284)。

本校为第一机构

先天淋巴样细胞(ILCs)是一个主要在组织驻留的淋巴细胞家族,是参与宿主调节组织稳态和机体发挥早期抗炎作用的重要细胞。ILCs发挥生物学功能与其细胞代谢密不可分,代谢反应可以帮助ILCs生长繁殖、对外界环境做出反应,以及...展开更多 先天淋巴样细胞(ILCs)是一个主要在组织驻留的淋巴细胞家族,是参与宿主调节组织稳态和机体发挥早期抗炎作用的重要细胞。ILCs发挥生物学功能与其细胞代谢密不可分,代谢反应可以帮助ILCs生长繁殖、对外界环境做出反应,以及与Th亚群相关的适应性免疫共同抗病原体感染。研究表明,细胞代谢在ILCs活化、增殖、释放细胞因子以及影响ILCs可塑性的过程中都发挥重要作用。现...

Innate lymphoid cells(ILCs)are a family of lymphocytes that reside mainly in tissues,and are important cellular components involved in the regulation of tissue homeostasis and the early anti-inflammatory effects of the body.The biological function of ILCs is closely rel...MORE Innate lymphoid cells(ILCs)are a family of lymphocytes that reside mainly in tissues,and are important cellular components involved in the regulation of tissue homeostasis and the early anti-inflammatory effects of the body.The biological function of ILCs is closely related to cell metabolism.Cell metabolism can help ILC...