期刊论文

Prediction ofβ-sitosterol as medicinal component in traditional Chinese medicine and its effects on the proliferation and migration of irradiated cervical cancer cells

中文

中南医学科学杂志

2095-1116

2024

52

4

506-511

10.15972/j.cnki.43-1509/r.2024.04.002

81402169:国家自然科学基金 23A0328:湖南省教育厅重点项目

本校为第一机构

目的预测宫颈癌差异基因的靶向中药关键药用成分,并分析其对辐照宫颈癌细胞增殖与迁移的影响。方法通过Coremine Medical、TCMSP、Uniprot以及Cytoscape数据库查找宫颈癌差异基因靶向中药及其药用成...展开更多 目的预测宫颈癌差异基因的靶向中药关键药用成分,并分析其对辐照宫颈癌细胞增殖与迁移的影响。方法通过Coremine Medical、TCMSP、Uniprot以及Cytoscape数据库查找宫颈癌差异基因靶向中药及其药用成分和对应靶点,并筛选出核心靶点和关键药用成分。通过STRING数据库分析关键药用成分对应靶点基因与宫颈癌差异基因的蛋白互作。采用MTT、细胞划痕实验和Western blotting实验检测关键药用成...

Aim To predict the targeted key medicinal components of traditional Chinese medicine for differentially expressed genes in cervical cancer,and analyze their effects on the proliferation and migration of irradiated cervical cancer cells.Methods Differentially-targeted tr...MORE Aim To predict the targeted key medicinal components of traditional Chinese medicine for differentially expressed genes in cervical cancer,and analyze their effects on the proliferation and migration of irradiated cervical cancer cells.Methods Differentially-targeted trad...