期刊论文

中文

中南医学科学杂志

2095-1116

2023

51

04

469-474

10.15972/j.cnki.43-1509/r.2023.04.001

国家科技重大专项(2018ZX10101002-004)；

本校为第一机构

目的研究超长链脂肪酸延伸酶2基因(ELOVL2)和溶质载体蛋白家族11A成员1基因(SLC11A1)单核苷酸多态性(SNP)与新疆维吾尔族人群结核病(TB)易感性的相关性。方法选择维吾尔族TB患者178例为TB组,142...展开更多 目的研究超长链脂肪酸延伸酶2基因(ELOVL2)和溶质载体蛋白家族11A成员1基因(SLC11A1)单核苷酸多态性(SNP)与新疆维吾尔族人群结核病(TB)易感性的相关性。方法选择维吾尔族TB患者178例为TB组,142例健康人为对照组。采用高通量测序检测各组ELOVL2基因rs1570069、rs2236212、rs3798719位点和SLC11A1基因rs17235409、rs17235416位点的多态性,分析不同遗传模型下基因多态性与TB易感性的相关性。结...

Aim To investigate the association of single nucleotide polymorphisms(SNPs)in the extra long chain fatty acid elongase 2 gene(ELOVL2)and the solute carrier protein family 11A member 1 gene(SLC11A1)with susceptibility to tuberculosis(TB)in the Xinjiang Uyghur population....MORE Aim To investigate the association of single nucleotide polymorphisms(SNPs)in the extra long chain fatty acid elongase 2 gene(ELOVL2)and the solute carrier protein family 11A member 1 gene(SLC11A1)with susceptibility to tuberculosis(TB)in the Xinjiang Uyghur population.Methods One hundred and seventy-eight Uyghur TB pati...