期刊论文

Advances in the molecular mechanisms underlying the effects of nanoparticles on cardiovascular health

中文

中南医学科学杂志

2095-1116

2023

51

1

142-145

10.15972/j.cnki.43-1509/r.2023.01.039

41877390:国家自然科学基金 SKLOG-202010:有机地球化学国家重点实验室开放基金

本校为第一机构

纳米颗粒可致心血管细胞生理结构改变及功能紊乱,甚至促使细胞死亡,进而导致心血管系统组织结构重塑和功能异常,诱发心血管病事件。纳米颗粒影响心血管健康的分子机制主要有氧化应激、遗传毒性、线粒体损伤、内质网应激、抑制自噬、诱导...展开更多 纳米颗粒可致心血管细胞生理结构改变及功能紊乱,甚至促使细胞死亡,进而导致心血管系统组织结构重塑和功能异常,诱发心血管病事件。纳米颗粒影响心血管健康的分子机制主要有氧化应激、遗传毒性、线粒体损伤、内质网应激、抑制自噬、诱导炎症、扰乱Ca2+信号和干扰脂代谢等。本文综述了纳米颗粒影响心血管健康的分子机制,为生态环境部门的科学决策提供...

Nanoparticles may alter the physiological structure of cells in the cardiovascular system and in turn lead to their dysfunction, and even promote cell death, which can lead to structural remodeling and dysfunction of the cardiovascular system, and induce cardiovascular ...MORE Nanoparticles may alter the physiological structure of cells in the cardiovascular system and in turn lead to their dysfunction, and even promote cell death, which can lead to structural remodeling and dysfunction of the cardiovascular system, and induce cardiovascular events. The molecular mechanisms by which nanopartic...