Autophagy is an evolutionarily conserved self-balancing process that plays an important role in maintaining cell homeostasis by targeting damaged organelles and misfolded proteins to lysosomes for degradation.Autophagy triggered by pathogen infection can specifically inhibit the replication of bacteria in the host cell,thereby protecting cells from harm.In turn,many pathogenic microorganisms developed diverse strategies to avoid autophagy.In this review,we focus on the interaction between intracellular bacteria and host autophagy.We then dicusses how intracellular bacteria are targeted and eli...