期刊论文

Design and Synthesis of Near-infrared Fluorescence Probe Based on Intramolecular Charge Transfer Mechanism for N2H4 Identification and Cell Imaging

中文

南华大学学报(自然科学版)

1673-0062

2020

34

2

83-90+97

10.19431/j.cnki.1673-0062.2020.02.013

(CX20190728):湖南省研究生科研创新项目

本校为第一机构

设计并合成了一种新型近红外异佛尔酮衍生物荧光探针(IS—NR—NH),利用肼(N 2H 4)特异性诱导的脱乙酰基反应,使得探针分子内电荷转移效应由弱变强,从而导致荧光增强,最终实现肼的选择性检测。该探针在HCO3^-,SO4^2-,Cl^-,SO3^2-,CO3^2-,Ac^-,Br^-,NO3^-,NO2^-,HSO3^-,I^-,F^-,Mg^2+,Co^2+,Cd^2+,Zn^2+,Pb^2+,Cr^3+,Fe^3+,Al^3+,Mn^2+,Ca^2+,Ba^2+等不同干扰物质存在下,仍能实现对N 2H 4的特异性比色及荧光识别。同时,在pH 7.4,二甲基亚砜与磷酸缓冲溶液的体积比为6∶4的体系中,探针IS—NR—NH对N 2H 4在0.02×10^-3~0.4×10^-3 mol/L的浓度范围内呈现出良好的线性关系,且检测限低至2×10^-7 mol...

A novel near-infrare disophorone-derivative based fluorescent probe(IS—NR—NH)was designed and synthesized,and the utilization of N 2H 4-induced the acetylation deprotection reaction made the intramolecular charge transfereffect turned on and eventually realized the selective detection of hydrazine.The probe can still achieve specific colorimetric and fluorescent recognition of N 2H 4 even in the presence of different analytes such as HCO3^-,SO4^2-,Cl^-,SO3^2-,CO3^2-,Ac^-,Br^-,NO3^-,NO2^-,HSO3^-,I^-,F^-,Mg^2+,Co^2+,Cd^2+,Zn^2+,Pb^2+,Cr^3+,Fe^3...