期刊论文

Study on Preparation and Properties of Biocompatible Silybin Imprinted Materials

中文

南华大学学报(自然科学版)

1673-0062

2019

33

4

79-88

10.19431/j.cnki.1673-0062.2019.04.008

南华大学大学生研究性学习及创新实验项目(2018XJXZ329) 南华大学研究生科研创新项目(2018KYY050).

本校为第一机构

以护肝活性天然产物水飞蓟宾(silybin)为模板分子,甲基丙烯酸(methacrylic,MAA)为功能单体,N-异丙基丙烯酰胺(N-isopropyl acrylamide,NIPAm)为热响应单体,生物相容性壳聚糖包裹Fe3 O4磁核作为载体,运用电子转移活化再生催化剂原子转移自由基聚合(activator regenerated by electron transfer atom transfer rad-ical polymerization,ARGET ATRP)制备水飞蓟宾磁性分子印迹聚合物(molecularly imprinted polymers,MMIPs),并运用傅里叶变换红外光谱(fourier transform infrared spectroscopy,FT-IR)、(thermogravimetric analysis,TGA)、(scanning electron microscope,SEM)和(X-ray diffraction,...

Using hepatoprotective active natural product silybin as template molecule,MAA as functional monomer,NIPAm as thermal response monomer,biocompatible chitosan coated Fe 3O 4 magnetic core as carrier,the silybin magnetic molecularly imprinted polymers (MMIPs) were successfully prepared by activator regenerated by electron transfer atom transfer radical polymerization (ARGET ATRP).The magnetic imprinted materials were respectively characterized by FT-IR,TGA,SEM and XRD.The dynamic adsorption behavior of MMIPs to silybin could be explained by pseud...