期刊论文

中文

中南医学科学杂志

2095-1116

2016

44

6

630-636

10.15972/j.cnki.43-1509/r.2016.06.007

2012AA063501:国家高技术研究发展计划（863计划） NHSYS04:疾病控制评价中心重点实验室建设经费 :湖南省重点学科建设项目

本校为第一机构

目的：系统评价复方苦参注射液辅助放化疗治疗鼻咽癌的有效性和安全性,为临床治疗提供循证参考。方法计算机检索The Cochrane Library、Medline、EMbase、CBM、CNKI、VIP、万方数据库,收集复方苦参注射液联合放化疗(试验组)对照单纯放化疗(对照组)治疗鼻咽癌的随机对照试验( RCTs),提取资料并评价质量后,采用RevMan 5.3统计软件对完全缓解率、Ⅲ~Ⅳ级口腔黏膜炎发生率、Ⅲ~Ⅳ级放射性皮炎发生率、Ⅲ~Ⅳ级白细胞减少发生率进行Meta分析。结果共纳入7项RCT,合计328例患者。 Meta分析结果显示,观察组患者治疗完全缓解率[OR＝2.00,95％CI(1.27,3.13),P

Objective To systematically evaluate the efficacy and safety of Compound Kushen Injection combined with radiation treatment and chemotherapy drugs in the treatment of esophageal carcinoma and to provide evidence-based advice for clinical treatment by using Meta-Analysis. Methods The Cochrane Library （Issue 6,2015）, Medline, EMbase, CBM, CNKI, VIP, WanFang Data were retrieved to collect the randomized controlled trials （RCT）that compared Compound Kushen Injection combined with radiation treatment and chemotherapy drugs （test group）with onl...