期刊论文

The Clinical Value of CMV-PP65 Antigen Detection in the Prevention of Cytomegalovirus Infection After Renal Transplantation

中文

中南医学科学杂志

2095-1116

2013

41

6

570-571,626

10.15972/j.cnki.43-1509/r.2013.06.007

衡阳市科委资助课题（2008KS022）；

本校为第一机构

目的 探讨巨细胞病毒PP65抗原(CMV-PP65)检测在预防肾移植术后巨细胞病毒(CMV)感染的临床价值.方法 采用间接免疫荧光法和酶联免疫捕获法检测52例肾移植受者术后CMV-PP65抗原和CMV-IgM抗体.结果 52例肾移植受者中CMV-PP65抗原检测阳性25例,CMV-IgM抗体检测阳性17例,随访3~6个月,共15例发生CMV病,CMV-PP65抗原检测均阳性,CMV-PP65抗原检测的敏感度及阴性预测值均高于CMV-IgM抗体检测;25例患者CMV-PP65抗原检测术后首次出现阳性的平均时间为4.2±3.3周,17例患者CMV-IgM抗体检测术后首次出现阳性的平均时间为8.7±5.8周,两者比较有显著差异性(P

Objective To investigate the clinical value of CMV-PP65 antigen detection in the prevention of cytomeg- alovirus infection after renal transplantation. Methods The CMV-PP65 antigen and CMV-IgM antibody of 52 cases with renal transplantation recipients were detected with the method of indirect immunofluorescence and enzyme-linked immune capture. Results Among the 52 cases of kidney transplant ,25 cases were tested positive with CMV-PP65 antigen, 17 cases were tested positive with CMV-IgM antibody. All patients were followed up for 3 -6 months, C...