期刊论文

中文

中南医学科学杂志

2095-1116

2012

40

1

73-75

10.15972/j.cnki.43-1509/r.2012.01.017

本校为第一机构

目的 探讨糖尿病对严重冠脉狭窄患者侧支循环形成的影响以及与血清ADMA浓度的关系. 方法 收集主要冠脉至少有一支狭窄程度在95％以上的112例冠心病患者,分为糖尿病与非糖尿病组,测定其血清ADMA浓度.采用Rentrop法对冠脉侧支循环进行分级.同时测定两组血清ADMA浓度. 结果 糖尿病组侧支循环形成不良的比例高于非糖尿病组(P=0.043,P＜0.05),其血清ADMA浓度也显著高于非糖尿病组(P=0.000,P＜0.01)；合并糖尿病的侧支循环不良患者血清ADMA浓度显著高于无糖尿病患者(P=0.001,P＜0.01).结论 糖尿病抑制严重冠脉狭窄的冠心病患者侧支循环的形成,且与患者血清ADMA浓度相关.

Objective To investigate the effects of diabetes mellitus on coronary collateral circulation and the relationship between serum levels of ADMA and degrees of coronary collateral circulation in diabetes mellitus patients.Methods 112 patients at least with the stenosis of one vessel 95% among coronary artery were consecutively enrolled.The 112 patients were divided into two groups：DM group and NDM group.Development of collaterals was classified by Rentrops method.The levels of ADMA were also determined.Results Compared with NDM group,poor CCC ...