期刊论文

Screening the Anti-inflammatory and Analgesic Effective Fractions from Sesamum Indicum Stem

中文

中南医学科学杂志

2095-1116

2008

36

6

735-737

10.3969/j.issn.2095-1116.2008.06.002

衡阳市科技局计划项目（No.2007KJ023）；

本校为第一机构

目的研究脂麻杆石油醚、氯仿、乙酸乙酯、甲醇、水部位萃取物的抗炎镇痛作用,筛选脂麻杆抗炎镇痛作用的有效部位。方法用二甲苯致小鼠耳廓肿胀,棉球致肉芽肿炎症模型,观察脂麻杆各溶剂部位的抗炎作用;以热板法试验了解其镇痛作用。结果脂麻杆石油醚、氯仿部位有显著抑制二甲苯致小鼠耳廓肿胀和小鼠棉球肉芽肿作用;热板法观察脂麻杆各溶剂部位的镇痛作用不明显。结论脂麻杆石油醚、氯仿溶剂部位有一定的抗炎作用。

Objective To screen the anti-inflammatory and analgesic effective fractions from the extraction of ligarine,chloroform,acetoacetate,methanol and water in stem of Sesamum indicum.Methods The anti-inflammatory effect was observed by the mouse auris-swell model and the cotton ball granulating proliferation test.The analgesic effect was tested by hot plate experiment.Results The extraction of chloroform and ligarine had significant anti-inflammatory effects,but the analgesic effect was not much evident. Conclusion The extraction of chloroform and...