Objective To investigate the effects of recombinant human adiponectin on metabolization of diabetic swines. Methods Ten chinese Guizhou swines were fed by high fat/high-sucrose fodder, and observed for 6 months. Then the ten diabetic swines were divided in to two groups: nolmal group and adiponectin group. We assessed the effects of recombinant adiponectin by detecting the change of plasma glucose levels and evaluating the insulin sensitivity. Plasma glucose was determined by commercially available enzymatic method test kits, and insulin sensi...