期刊论文

Effect of Eradication Therapy for Helicobacter Pylori on Reflux Esophagitis

中文

中南医学科学杂志

2095-1116

2006

34

4

569-571

10.3969/j.issn.2095-1116.2006.04.028

本校为其他机构

目的 探讨幽门螺杆菌(Hp)清除治疗对反流性食管炎(RE)疗效的影响.方法 将已确诊的58例Hp阳性的RE病人随机分为两组.其中观察组30例,对照组28例.两组病人均给予口服质子泵抑制剂和对症治疗,观察组在治疗的同时加用克拉霉素和阿莫西林作Hp抗菌治疗,对照组则不作Hp抗菌治疗.总疗程均为4周.疗程结束后比较两组病人的症状、胃镜下黏膜损害的改善程度.结果 两组病人的症状改善程度差异无显著性,胃镜下黏膜损害改善程度差异亦无显著性.结论 清除Hp与否对于RE病人,无论是临床症状的控制,还是黏膜损害性病变的改善并不产生显著影响.

Objective To investigate the effect of eradication therapy for helicobacter pylofi on reflux esophagitis. Methods Fifty- eight patients with reflux esophagitis accompanied by Helicobacter pylori were randomly divided into two groups,30 cases in observation group and 28 cases in control group. H（＋ ） - pump inhibitor were administrated in two groups for 4 weeks, in addition, eradication therapy by clarithromycin and amoxicillin for helicobacter pylori in observation group, not in control group. After that, the improvement degree of symptoms an...