期刊论文

中文

中南医学科学杂志

2095-1116

2005

33

3

322-325

10.3969/j.issn.2095-1116.2005.03.008

01SSY2008-6:湖南省科技厅科研项目 4-01-JY-01C198,02C398:湖南省教育厅科学研究项目

本校为第一机构

目的了解淋病奈瑟菌流行株对大环内酯类药物的敏感性,为淋病的防治提供实验依据.方法采用琼脂稀释法对分离出的101株淋球菌流行株进行了药物敏感性测定.结果在测定的4种大环内酯类药物中,淋球菌对阿奇霉素敏感性最高,达100%;其次为罗红霉素,为96.04%.交沙霉素耐药率最高,达36.63%;红霉素耐药率其次,为20.79%;罗红霉素耐药率仅为3.96%.结论阿奇霉素可作为衡阳地区淋病治疗的首选药物,罗红霉素可作为淋病治疗的替代性药物.淋球菌对大环内酯类药物有一定的不完全交叉耐药性.

Objective To evaluate the antibiotic susceptibility of Neisseria gonorrhoeae epidemic strains to macrolides in Hengyang and provide a referrence for the prevention and treatment of gonorrhea. Methods 101 gonococcal isolates obtained from 2003 to 2004 in Hengyang city , Hunan province , were tested for their susceptibilities to macrolides using agar dilution method. Results Of all these 4 macrolides, the higher susceptibilities to gonococci were azithromycin and roxithromycin, in turn , the percentages of susceptibility were 100%, 96.04% , respectively .On the other hand , the higher resistance...