期刊论文

The Susceptibility of Neisseria Gonorrhoeae to Seven Antibiotic Agents

中文

中南医学科学杂志

2095-1116

2004

32

3

290-293

10.3969/j.issn.2095-1116.2004.03.005

湖南省教育厅基金资助 （课题编号 :0 2C3 98）；

本校为第一机构

目的了解江门地区淋球菌流行株对抗生素的敏感性,为淋病的防治提供试验依据.方法采用琼脂稀释法对95株淋球菌临床分离株进行了药物敏感性测定.结果在测定的7种抗生素中,对淋球菌敏感性较高的5种抗生素依次为阿奇霉素、罗红霉素、红霉素、头孢曲松和壮观霉素,其敏感率分别为100.0%、98.9%、98.9%、95.8%和94.7%.而淋球菌耐药性较高的2种抗生素依次为交沙霉素和头孢唑啉钠,耐药率均为8.4%.结论阿奇霉素、头孢曲松和壮观霉素仍可作为江门地区淋病治疗的首选药物,但淋球菌对头孢曲松和壮观霉素已出现耐药株,应引起临床医师的高度警惕;罗红霉素、红霉素可作为江门地区淋病治疗的替代性药物.

Objective To evaluate the antibiotic susceptibility of Neisseria gonorrhoeae epidemic strains in jiangmen and to provide a referrence for the prevention and treatment of gonorrhea. Methods 95 gonococcal isolates were tested for their susceptibilities to 7 antibiotic agents using agar dilution method. Result Of all these 7 antibiotic agents , the higher susceptibilities to gonococci were azithromycin , roxithromycin , erythromycin , ceftriaxone , spectinomycin in turn , the percentages of susceptibility were 100.0% , 98.9% , 98.9% , 95.8% , 94.7% respectively .On the other hand , the higher res...