期刊论文

Clinical Significance of Urinary NAG Determination for Early Diagnosis of Diabetic Nephropathy

中文

中南医学科学杂志

2095-1116

1999

1

17-18

衡阳市科委资助

本校为第一机构

检测５２例非胰岛素依赖性糖尿病（ＮＩＤＤＭ）患者尿Ｎ－乙酰－β－Ｄ－氨基葡萄糖苷酶（ＮＡＧ）活性和尿微量白蛋白，结果显示，ＮＩＤＤＭ患者尿ＮＡＧ活性显著高于对照组，与尿ｍＡＬＢ呈显著正相关，尿ＮＡＧ和ｍＡＬＢ增高百分率分别为５７．７％和５９．６％，两者差异无显著性，提示尿ＮＡＧ诊断早期糖尿病肾病（ＤＮ）的敏感性与ｍＡＬＢ相仿。同时监测糖尿病患者尿ＮＡＧ的ｍＡＬＢ，有助于提高早期糖尿病肾病诊断的准确

Urinary N acetyl β D glucosaminidase(NAG) activity and microalbumin(mALB) were determined in 52 patients with non insulin dependent diabetes mellitus(NIDDM).The results showed that NAG activity increased remarkably in NIDDM than in the control and had a significant correlation with mALB.The percentage of increased value of NAG and mALB were 57.7% and 59.6% respectively.Between them there was no significant difference(P>0.05),which suggested that NAG was similar to mALB in sensitivity for diagnosing diabetic nephropathy at its early stage.It se...