期刊论文

中文

中南医学科学杂志

2095-1116

1999

03

273-276

本校为第一机构

为探讨降逆汤对支气管哮喘（ 简称哮喘） 并胃食道返流（ Ｇ Ｅ Ｒ） 患者肺功能与气道反应性的影响，本研究将５４ 例哮喘并 Ｇ Ｅ Ｒ 患者随机分为降逆汤组、西药组与对照组，前两组分别给予降逆汤与雷尼替丁等西药治疗６ 周。结果显示：降逆汤治疗后患者哮喘与 Ｇ Ｅ Ｒ 临床积分明显降低，内窥镜下食管炎明显改善，肺功能指标显著增加，气道反应性则明显降低（ Ｐ 均＜ ０ ．０１） ；且和对照组比较，差异有非常显著性（ Ｐ 均＜ ０ ．０１） ，但与西药组比较，差异无统计学意义（ Ｐ 均＞ ０ ．０５） 。提示降逆汤通过治疗 Ｇ Ｅ Ｒ 而改善哮喘并 Ｇ Ｅ Ｒ患者之肺功能与气道反应性。

To study the effects of Jiangni Decoction on pulmonary function as well as airway responsiveness in asthmatics with associated gastroesophageal reflx(GER),54 patients with asthma and GER were divided into 3 groups randomly:Jiangni Decoction group(n=18),western drugs group(n=18) and control group(n=18). In the Jiangni Decoction and western drugs groups,patients were administered with Jiangni Decoction and Ranitidine as well as Cisapride for 6 weeks,respectively.The results showed that the refluent and asthmatic symptoms were significantly relieved and the VC,VC% Pred,FVC,FVC% Pred,FEV 1,FEV 1/F...